AutismKB 2.0

Annotation Detail for YAF2


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Basic Information Top
Gene Symbol:YAF2 ( DKFZp779H1820,MGC41856 )
Gene Full Name: YY1 associated factor 2
Band: 12q12
Quick LinksEntrez ID:10138; OMIM: 607534; Uniprot ID:YAF2_HUMAN; ENSEMBL ID: ENSG00000015153; HGNC ID: 17363
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal107 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain38 / 110098934
cervix0 / 481710 
connective tissue6 / 14925540
ear2 / 16212123
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye4 / 21105418
heart2 / 8962622
intestine4 / 23447217
kidney9 / 21177742
larynx0 / 241450 
liver2 / 2077439
lung8 / 33697423
lymph0 / 442700 
lymph node3 / 9161032
mammary gland5 / 15327132
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta11 / 28082539
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach3 / 9661931
testis6 / 33044218
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206238_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.75
Adipocyte7.3
AdrenalCortex7.95
Adrenalgland6.4
Amygdala7.95
Appendix8.55
AtrioventricularNode6
BDCA4+_DentriticCells7.7
Bonemarrow7.25
BronchialEpithelialCells6.75
CD105+_Endothelial7.25
CD14+_Monocytes7.9
CD19+_BCells(neg._sel.)11.8
CD33+_Myeloid8.9
CD34+9.55
CD4+_Tcells8.35
CD56+_NKCells9.05
CD71+_EarlyErythroid6.85
CD8+_Tcells7.35
CardiacMyocytes9.65
Caudatenucleus6.35
Cerebellum5.95
CerebellumPeduncles8.8
CiliaryGanglion5.25
CingulateCortex7.6
Colorectaladenocarcinoma7.25
DorsalRootGanglion6.35
FetalThyroid7.1
Fetalbrain7.4
Fetalliver6.2
Fetallung5.65
GlobusPallidus5.75
Heart12.05
Hypothalamus8.3
Kidney6.15
Leukemia_chronicMyelogenousK-5626.45
Leukemia_promyelocytic-HL-606.45
Leukemialymphoblastic(MOLT-4)5.65
Liver9.9
Lung8.15
Lymphnode6.35
Lymphoma_burkitts(Daudi)9.45
Lymphoma_burkitts(Raji)10.5
MedullaOblongata6.45
OccipitalLobe6.4
OlfactoryBulb5.8
Ovary5.15
Pancreas5.8
PancreaticIslet7.75
ParietalLobe7.85
Pituitary8.3
Placenta6.6
Pons7
PrefrontalCortex8.75
Prostate8.7
Salivarygland5.9
SkeletalMuscle12.8
Skin6.6
SmoothMuscle8.35
Spinalcord7.45
SubthalamicNucleus7.75
SuperiorCervicalGanglion10.5
TemporalLobe6.7
Testis6.1
TestisGermCell6.05
TestisIntersitial6.5
TestisLeydigCell7.35
TestisSeminiferousTubule6.35
Thalamus7.35
Thymus5.6
Thyroid9.3
Tongue7.95
Tonsil7.3
Trachea5.95
TrigeminalGanglion7.45
Uterus5.75
UterusCorpus7.2
WholeBlood8.15
Wholebrain7.75
colon7.1
pineal_day9.1
pineal_night8.98
retina8.3
small_intestine6.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14080_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.41 ± 0.29
Basal Forebrain10.79 ± 0.18
Basal Part of Pons11.01 ± 0.32
Cerebellar Cortex11.03 ± 0.22
Cerebellar Nuclei10.95 ± 0.27
Claustrum11.17 ± 0.25
Epithalamus10.84 ± 0.31
Frontal Lobe11.12 ± 0.34
Globus Pallidus11.03 ± 0.37
Hypothalamus10.95 ± 0.45
Insula11.16 ± 0.34
Limbic Lobe11.26 ± 0.27
Mesencephalon11.04 ± 0.37
Myelencephalon11.03 ± 0.31
Occipital Lobe11.06 ± 0.3
Parietal Lobe11.09 ± 0.29
Pontine Tegmentum11.1 ± 0.26
Striatum10.65 ± 0.37
Subthalamus11.11 ± 0.28
Temporal Lobe11.18 ± 0.24
Thalamus10.95 ± 0.21
White Matter10.47 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Yaf2CBCerebellum14.53
18.62
Yaf2CTXCerebral cortex41.09
33.52
Yaf2HIPHippocampal region29.19
41.62
Yaf2HPFHippocampal formation26.59
32.21
Yaf2HYHypothalamus8.58
7.23
Yaf2LSXLateral septal complex13.79
10.54
Yaf2MBMidbrain15.73
16.52
Yaf2MYMedulla17.03
22.2
Yaf2OLFOlfactory bulb19.36
16.94
Yaf2PPons14.52
19.1
Yaf2PALPallidum13.56
14.3
Yaf2RHPRetrohippocampal region23.28
21.61
Yaf2sAMYStriatum-like amygdalar nuclei8.9
6.98
Yaf2STRStriatum6.14
5.4
Yaf2STRdStriatum dorsal region4.56
4.6
Yaf2STRvStriatum ventral region7.2
5.44
Yaf2THThalamus22.38
21.62
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00427015 25 136 160 SPPASSAASADQHSQSGSSSDNTER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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