AutismKB 2.0

Annotation Detail for CDH17


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Basic Information Top
Gene Symbol:CDH17 ( CDH16,FLJ26931,HPT-1,HPT1,MGC138218,MGC142024 )
Gene Full Name: cadherin 17, LI cadherin (liver-intestine)
Band: 8q22.1
Quick LinksEntrez ID:1015; OMIM: 603017; Uniprot ID:CAD17_HUMAN; ENSEMBL ID: ENSG00000079112; HGNC ID: 1756
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult78 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor42 / 114246367
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal55 / 336030716
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine98 / 234472417
kidney0 / 2117770 
larynx0 / 241450 
liver7 / 20774333
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle6 / 10771555
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach4 / 9661941
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209847_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.55
Adipocyte4.25
AdrenalCortex6.65
Adrenalgland3.85
Amygdala4.35
Appendix7.35
AtrioventricularNode5.85
BDCA4+_DentriticCells4.55
Bonemarrow5.2
BronchialEpithelialCells3.9
CD105+_Endothelial4.2
CD14+_Monocytes4.6
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.25
CD34+5.1
CD4+_Tcells4.15
CD56+_NKCells4.95
CD71+_EarlyErythroid3.9
CD8+_Tcells3.6
CardiacMyocytes5.85
Caudatenucleus3.9
Cerebellum3.4
CerebellumPeduncles6.35
CiliaryGanglion3.8
CingulateCortex4.6
Colorectaladenocarcinoma4.25
DorsalRootGanglion5.15
FetalThyroid4.15
Fetalbrain4.2
Fetalliver3.8
Fetallung3.45
GlobusPallidus4
Heart5.65
Hypothalamus4.65
Kidney3.5
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.55
Liver6.25
Lung4.45
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.45
Lymphoma_burkitts(Raji)5.95
MedullaOblongata5.65
OccipitalLobe3.85
OlfactoryBulb3.3
Ovary4.25
Pancreas374.1
PancreaticIslet4.6
ParietalLobe4.9
Pituitary5.2
Placenta4.35
Pons4.65
PrefrontalCortex4.8
Prostate5
Salivarygland3.5
SkeletalMuscle4.8
Skin5.4
SmoothMuscle4.8
Spinalcord4.55
SubthalamicNucleus4.5
SuperiorCervicalGanglion7.45
TemporalLobe4.55
Testis3.55
TestisGermCell3.5
TestisIntersitial4
TestisLeydigCell4.6
TestisSeminiferousTubule4.3
Thalamus4.45
Thymus3.35
Thyroid5.15
Tongue4.5
Tonsil4.2
Trachea3.55
TrigeminalGanglion6.55
Uterus3.3
UterusCorpus4.6
WholeBlood4.45
Wholebrain3.2
colon592.85
pineal_day5.02
pineal_night4.88
retina5.075
small_intestine360.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P111947
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.98 ± 0.99
Basal Forebrain1.57 ± 0.2
Basal Part of Pons1.19 ± 0.35
Cerebellar Cortex1.32 ± 0.57
Cerebellar Nuclei1.79 ± 0.73
Claustrum2.39 ± 0.86
Epithalamus1.24 ± 0.73
Frontal Lobe1.34 ± 0.57
Globus Pallidus2.05 ± 0.31
Hypothalamus1.62 ± 0.73
Insula1.46 ± 0.41
Limbic Lobe1.49 ± 0.57
Mesencephalon1.67 ± 0.68
Myelencephalon1.53 ± 0.64
Occipital Lobe1.58 ± 0.6
Parietal Lobe1.5 ± 0.72
Pontine Tegmentum1.55 ± 0.65
Striatum1.71 ± 0.56
Subthalamus1.65 ± 0.59
Temporal Lobe1.44 ± 0.69
Thalamus1.5 ± 0.57
White Matter1.96 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdh17CBCerebellum0.3
0.6
Cdh17CTXCerebral cortex0.31
0.37
Cdh17HIPHippocampal region0.16
0.14
Cdh17HPFHippocampal formation0.13
0.17
Cdh17HYHypothalamus0.09
0.08
Cdh17LSXLateral septal complex0.76
1.22
Cdh17MBMidbrain0.07
0.16
Cdh17MYMedulla0.83
0.95
Cdh17OLFOlfactory bulb0.94
1.89
Cdh17PPons0.2
0.4
Cdh17PALPallidum0.16
0.15
Cdh17RHPRetrohippocampal region0.07
0.19
Cdh17sAMYStriatum-like amygdalar nuclei0.41
0.36
Cdh17STRStriatum0.21
0.33
Cdh17STRdStriatum dorsal region0.17
0.2
Cdh17STRvStriatum ventral region0.09
0.55
Cdh17THThalamus0.14
0.16
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001871 30 670 699 DYTGLFFCHPLSAPGSLIFEATDDDQHLFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018