AutismKB 2.0

Annotation Detail for ABI2


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Basic Information Top
Gene Symbol:ABI2 ( ABI-2,ABI2B,AIP-1,AblBP3,SSH3BP2,argBPIA,argBPIB )
Gene Full Name: abl-interactor 2
Band: 2q33.2
Quick LinksEntrez ID:10152; OMIM: 606442; Uniprot ID:ABI2_HUMAN; ENSEMBL ID: ENSG00000138443; HGNC ID: 24011
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst4 / 6231964
fetus96 / 564012170
neonate3 / 3109796
infant3 / 23620127
juvenile2 / 5555635
adult127 / 193912165
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma8 / 8282396
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor28 / 263845106
glioma22 / 106883205
head and neck tumor7 / 13630251
kidney tumor5 / 6895972
leukemia6 / 9584262
liver tumor6 / 9635962
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal370 / 3360307110
ovarian tumor9 / 76682117
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor7 / 12494956
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder3 / 29757100
blood4 / 12347832
bone5 / 7165569
bone marrow2 / 4880140
brain208 / 1100989188
cervix2 / 4817141
connective tissue6 / 14925540
ear2 / 16212123
embryonic tissue19 / 21572288
esophagus1 / 2020949
eye19 / 21105490
heart5 / 8962655
intestine10 / 23447242
kidney12 / 21177756
larynx1 / 2414541
liver9 / 20774343
lung27 / 33697480
lymph0 / 442700 
lymph node7 / 9161076
mammary gland5 / 15327132
mouth4 / 6705259
muscle15 / 107715139
nerve1 / 1576863
ovary9 / 10205188
pancreas16 / 21481274
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta11 / 28082539
prostate9 / 18934547
salivary gland0 / 201550 
skin14 / 21057466
spleen2 / 5395237
stomach3 / 9661931
testis47 / 330442142
thymus6 / 8113173
thyroid5 / 47473105
tonsil1 / 1699958
trachea5 / 5241395
umbilical cord2 / 13680146
uterus18 / 23287877
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211793_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts23.3
Adipocyte8.45
AdrenalCortex8.8
Adrenalgland7.35
Amygdala11.8
Appendix9.65
AtrioventricularNode6.5
BDCA4+_DentriticCells9.8
Bonemarrow8.8
BronchialEpithelialCells8.5
CD105+_Endothelial6.85
CD14+_Monocytes8.2
CD19+_BCells(neg._sel.)9.05
CD33+_Myeloid9.55
CD34+10.75
CD4+_Tcells9.55
CD56+_NKCells8.9
CD71+_EarlyErythroid8.05
CD8+_Tcells8.05
CardiacMyocytes11.1
Caudatenucleus8.05
Cerebellum11.25
CerebellumPeduncles10.2
CiliaryGanglion6.35
CingulateCortex9.05
Colorectaladenocarcinoma9.4
DorsalRootGanglion6.5
FetalThyroid8.35
Fetalbrain10.85
Fetalliver7.6
Fetallung10.1
GlobusPallidus6.4
Heart10.95
Hypothalamus9.1
Kidney7.35
Leukemia_chronicMyelogenousK-56210.35
Leukemia_promyelocytic-HL-609
Leukemialymphoblastic(MOLT-4)8.9
Liver11.75
Lung9.55
Lymphnode7.4
Lymphoma_burkitts(Daudi)11.05
Lymphoma_burkitts(Raji)11.95
MedullaOblongata8.1
OccipitalLobe8.6
OlfactoryBulb6.8
Ovary5.75
Pancreas6.7
PancreaticIslet11.35
ParietalLobe9
Pituitary11.55
Placenta9
Pons8.2
PrefrontalCortex10.75
Prostate10.4
Salivarygland6.9
SkeletalMuscle9.95
Skin6.7
SmoothMuscle10.6
Spinalcord9.3
SubthalamicNucleus7.65
SuperiorCervicalGanglion10.95
TemporalLobe7.95
Testis16.9
TestisGermCell11.65
TestisIntersitial8.95
TestisLeydigCell13.6
TestisSeminiferousTubule12.1
Thalamus8.75
Thymus7.75
Thyroid11.1
Tongue8.3
Tonsil8.35
Trachea8.8
TrigeminalGanglion9.2
Uterus6.9
UterusCorpus8.25
WholeBlood9.35
Wholebrain9.3
colon8.6
pineal_day10.54
pineal_night10.14
retina10.325
small_intestine8.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P933418
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.16 ± 0.44
Basal Forebrain8.26 ± 0.29
Basal Part of Pons8.17 ± 0.23
Cerebellar Cortex7.9 ± 0.27
Cerebellar Nuclei7.57 ± 0.32
Claustrum7.89 ± 0.68
Epithalamus8.43 ± 0.32
Frontal Lobe8.25 ± 0.39
Globus Pallidus7.41 ± 0.29
Hypothalamus8.34 ± 0.27
Insula8.36 ± 0.3
Limbic Lobe8.09 ± 0.59
Mesencephalon7.98 ± 0.38
Myelencephalon8.06 ± 0.43
Occipital Lobe7.82 ± 0.63
Parietal Lobe8.13 ± 0.41
Pontine Tegmentum8.08 ± 0.4
Striatum8.26 ± 0.66
Subthalamus7.99 ± 0.16
Temporal Lobe8.31 ± 0.37
Thalamus7.92 ± 0.43
White Matter7.02 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abi2CBCerebellum19.81
22.52
Abi2CTXCerebral cortex100
100
Abi2HIPHippocampal region100
100
Abi2HPFHippocampal formation100
100
Abi2HYHypothalamus27.06
21.07
Abi2LSXLateral septal complex58.5
53.48
Abi2MBMidbrain27.68
24.91
Abi2MYMedulla30.09
32.67
Abi2OLFOlfactory bulb83.08
88.87
Abi2PPons27.65
27.97
Abi2PALPallidum30.9
27.98
Abi2RHPRetrohippocampal region91.89
93.71
Abi2sAMYStriatum-like amygdalar nuclei74.71
62.45
Abi2STRStriatum100
88.37
Abi2STRdStriatum dorsal region100
100
Abi2STRvStriatum ventral region97.85
80.82
Abi2THThalamus16.48
13.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00466171 16 139 154 KPIDYTILDDIGHGVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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