AutismKB 2.0

Annotation Detail for LPAR6


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Basic Information Top
Gene Symbol:LPAR6 ( ARWH1,LAH3,MGC120358,P2RY5,P2Y5 )
Gene Full Name: lysophosphatidic acid receptor 6
Band: 13q14.2
Quick LinksEntrez ID:10161; OMIM: 609239; Uniprot ID:LPAR6_HUMAN; ENSEMBL ID: ENSG00000139679; HGNC ID: 15520
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus19 / 56401233
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal154 / 336030745
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland3 / 3319790
ascites0 / 400150 
bladder3 / 29757100
blood2 / 12347816
bone1 / 7165513
bone marrow5 / 48801102
brain17 / 110098915
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus2 / 2020998
eye1 / 2110544
heart5 / 8962655
intestine5 / 23447221
kidney6 / 21177728
larynx0 / 241450 
liver7 / 20774333
lung11 / 33697432
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth3 / 6705244
muscle9 / 10771583
nerve1 / 1576863
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx6 / 41328145
pituitary gland3 / 16585180
placenta40 / 280825142
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen3 / 5395255
stomach5 / 9661951
testis15 / 33044245
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus13 / 23287855
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218589_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.85
Adipocyte6.75
AdrenalCortex8.25
Adrenalgland6.85
Amygdala7.55
Appendix11.15
AtrioventricularNode7.35
BDCA4+_DentriticCells30.05
Bonemarrow6.9
BronchialEpithelialCells7.45
CD105+_Endothelial8.5
CD14+_Monocytes184.65
CD19+_BCells(neg._sel.)7.1
CD33+_Myeloid73.4
CD34+8.95
CD4+_Tcells54.35
CD56+_NKCells42.3
CD71+_EarlyErythroid6.6
CD8+_Tcells23.4
CardiacMyocytes9.35
Caudatenucleus6.4
Cerebellum5.8
CerebellumPeduncles8.05
CiliaryGanglion8.25
CingulateCortex7.25
Colorectaladenocarcinoma6.9
DorsalRootGanglion10.45
FetalThyroid8.05
Fetalbrain6.85
Fetalliver10.35
Fetallung16.9
GlobusPallidus5.4
Heart9.55
Hypothalamus8.85
Kidney5.95
Leukemia_chronicMyelogenousK-5626.25
Leukemia_promyelocytic-HL-606.2
Leukemialymphoblastic(MOLT-4)34.1
Liver9.4
Lung7.7
Lymphnode38.4
Lymphoma_burkitts(Daudi)9.25
Lymphoma_burkitts(Raji)9.9
MedullaOblongata6.45
OccipitalLobe6.35
OlfactoryBulb11
Ovary6.45
Pancreas5.75
PancreaticIslet8.35
ParietalLobe7.7
Pituitary8.25
Placenta7
Pons6.8
PrefrontalCortex8.6
Prostate13.1
Salivarygland41.4
SkeletalMuscle8.95
Skin10.25
SmoothMuscle7.9
Spinalcord11.5
SubthalamicNucleus6.55
SuperiorCervicalGanglion10.05
TemporalLobe6.55
Testis5.9
TestisGermCell5.8
TestisIntersitial6.8
TestisLeydigCell7.85
TestisSeminiferousTubule6
Thalamus7.75
Thymus5.4
Thyroid11.25
Tongue12.65
Tonsil11.3
Trachea11.45
TrigeminalGanglion8.75
Uterus29.75
UterusCorpus6.6
WholeBlood74.9
Wholebrain5.45
colon8.25
pineal_day9.58
pineal_night9.84
retina10.025
small_intestine10.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12253_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.35 ± 0.95
Basal Forebrain1.76 ± 0.28
Basal Part of Pons1.62 ± 0.45
Cerebellar Cortex1.63 ± 0.66
Cerebellar Nuclei2.03 ± 0.79
Claustrum2.74 ± 0.97
Epithalamus2.29 ± 0.85
Frontal Lobe1.7 ± 0.63
Globus Pallidus2.54 ± 0.57
Hypothalamus1.88 ± 0.83
Insula1.55 ± 0.41
Limbic Lobe1.77 ± 0.61
Mesencephalon1.94 ± 0.73
Myelencephalon1.88 ± 0.66
Occipital Lobe1.78 ± 0.69
Parietal Lobe1.91 ± 0.93
Pontine Tegmentum1.94 ± 0.8
Striatum2.09 ± 0.77
Subthalamus1.91 ± 0.71
Temporal Lobe1.8 ± 0.74
Thalamus1.76 ± 0.59
White Matter2.07 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
P2ry5CBCerebellum3.06
3.48
P2ry5CTXCerebral cortex2.68
2.5
P2ry5HIPHippocampal region3.19
2.97
P2ry5HPFHippocampal formation2.43
2.18
P2ry5HYHypothalamus0.83
1.15
P2ry5LSXLateral septal complex5.28
7.07
P2ry5MBMidbrain0.89
1.12
P2ry5MYMedulla2.66
2.97
P2ry5OLFOlfactory bulb6.19
6.87
P2ry5PPons1.29
2.06
P2ry5PALPallidum0.98
0.95
P2ry5RHPRetrohippocampal region1.14
1.06
P2ry5sAMYStriatum-like amygdalar nuclei0.57
0.4
P2ry5STRStriatum1.96
1.72
P2ry5STRdStriatum dorsal region1.97
1.67
P2ry5STRvStriatum ventral region1.67
1.08
P2ry5THThalamus1.66
1.87
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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