AutismKB 2.0

Annotation Detail for WASF2


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Basic Information Top
Gene Symbol:WASF2 ( SCAR2,WAVE2,dJ393P12.2 )
Gene Full Name: WAS protein family, member 2
Band: 1p36.11
Quick LinksEntrez ID:10163; OMIM: 605875; Uniprot ID:WASF2_HUMAN; ENSEMBL ID: ENSG00000158195; HGNC ID: 12733
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus28 / 56401249
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult115 / 193912159
embryoid body4 / 7076156
blastocyst7 / 62319112
fetus57 / 564012101
neonate9 / 31097289
infant1 / 2362042
juvenile2 / 5555635
adult229 / 1939121118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor6 / 34366174
chondrosarcoma8 / 8282396
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor19 / 119369159
germ cell tumor12 / 26384545
glioma9 / 10688384
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor7 / 9635972
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal137 / 336030740
ovarian tumor9 / 76682117
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor5 / 9025755
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor18 / 34366523
chondrosarcoma5 / 8282360
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor54 / 263845204
glioma18 / 106883168
head and neck tumor18 / 136302132
kidney tumor8 / 68959116
leukemia8 / 9584283
liver tumor6 / 9635962
lung tumor4 / 10312738
lymphoma10 / 71755139
non-neoplasia12 / 97250123
normal305 / 336030790
ovarian tumor9 / 76682117
pancreatic tumor24 / 104616229
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor25 / 124949200
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites17 / 40015424
bladder0 / 297570 
blood9 / 12347872
bone4 / 7165555
bone marrow2 / 4880140
brain18 / 110098916
cervix7 / 48171145
connective tissue10 / 14925566
ear1 / 1621261
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye6 / 21105428
heart4 / 8962644
intestine11 / 23447246
kidney4 / 21177718
larynx3 / 24145124
liver11 / 20774352
lung19 / 33697456
lymph0 / 442700 
lymph node2 / 9161021
mammary gland10 / 15327165
mouth3 / 6705244
muscle0 / 1077150 
nerve1 / 1576863
ovary12 / 102051117
pancreas9 / 21481241
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta16 / 28082556
prostate15 / 18934579
salivary gland2 / 2015599
skin8 / 21057437
spleen0 / 539520 
stomach3 / 9661931
testis8 / 33044224
thymus5 / 8113161
thyroid1 / 4747321
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord1 / 1368073
uterus21 / 23287890
vascular0 / 517800 
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites2 / 4001549
bladder0 / 297570 
blood12 / 12347897
bone8 / 71655111
bone marrow4 / 4880181
brain73 / 110098966
cervix20 / 48171415
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus0 / 202090 
eye15 / 21105471
heart10 / 89626111
intestine21 / 23447289
kidney16 / 21177775
larynx1 / 2414541
liver10 / 20774348
lung18 / 33697453
lymph10 / 44270225
lymph node12 / 91610130
mammary gland32 / 153271208
mouth10 / 67052149
muscle5 / 10771546
nerve1 / 1576863
ovary16 / 102051156
pancreas29 / 214812135
parathyroid1 / 2053948
pharynx9 / 41328217
pituitary gland0 / 165850 
placenta47 / 280825167
prostate21 / 189345110
salivary gland1 / 2015549
skin39 / 210574185
spleen7 / 53952129
stomach2 / 9661920
testis46 / 330442139
thymus11 / 81131135
thyroid2 / 4747342
tonsil5 / 16999294
trachea3 / 5241357
umbilical cord15 / 136801096
uterus38 / 232878163
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221725_at
Cell line Expression level Expression bar
721_B_lymphoblasts245.55
Adipocyte126.25
AdrenalCortex46.95
Adrenalgland76.55
Amygdala67.2
Appendix85.3
AtrioventricularNode56.15
BDCA4+_DentriticCells293.15
Bonemarrow120.85
BronchialEpithelialCells164.2
CD105+_Endothelial135.15
CD14+_Monocytes440
CD19+_BCells(neg._sel.)394
CD33+_Myeloid366.15
CD34+193.85
CD4+_Tcells175.35
CD56+_NKCells366.35
CD71+_EarlyErythroid405.75
CD8+_Tcells153.1
CardiacMyocytes143.05
Caudatenucleus57.6
Cerebellum61.1
CerebellumPeduncles41.7
CiliaryGanglion47.35
CingulateCortex53.8
Colorectaladenocarcinoma105.35
DorsalRootGanglion72.65
FetalThyroid103.4
Fetalbrain51.05
Fetalliver81.9
Fetallung127.95
GlobusPallidus30.75
Heart76.75
Hypothalamus82.7
Kidney58.1
Leukemia_chronicMyelogenousK-562182.9
Leukemia_promyelocytic-HL-60184.05
Leukemialymphoblastic(MOLT-4)150.65
Liver85.95
Lung241.85
Lymphnode89.1
Lymphoma_burkitts(Daudi)85
Lymphoma_burkitts(Raji)505.2
MedullaOblongata56.35
OccipitalLobe45.65
OlfactoryBulb109.2
Ovary64.8
Pancreas43.5
PancreaticIslet87.9
ParietalLobe39.85
Pituitary73.25
Placenta316.9
Pons33.6
PrefrontalCortex101.65
Prostate139.1
Salivarygland61.45
SkeletalMuscle57.6
Skin43.1
SmoothMuscle115.5
Spinalcord118
SubthalamicNucleus38.75
SuperiorCervicalGanglion31.85
TemporalLobe34.95
Testis144.75
TestisGermCell150
TestisIntersitial87
TestisLeydigCell93.4
TestisSeminiferousTubule88.5
Thalamus63.45
Thymus143.35
Thyroid163.9
Tongue95.9
Tonsil113.7
Trachea75.05
TrigeminalGanglion59.2
Uterus125.9
UterusCorpus44.75
WholeBlood429.7
Wholebrain52.4
colon73.5
pineal_day69.9
pineal_night56.94
retina144.175
small_intestine88.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P41461
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.98 ± 0.39
Basal Forebrain9.37 ± 0.41
Basal Part of Pons8.81 ± 0.28
Cerebellar Cortex8.8 ± 0.16
Cerebellar Nuclei9.62 ± 0.4
Claustrum9.34 ± 0.37
Epithalamus9.68 ± 0.27
Frontal Lobe8.95 ± 0.44
Globus Pallidus10.39 ± 0.27
Hypothalamus9.08 ± 0.38
Insula8.88 ± 0.23
Limbic Lobe8.91 ± 0.51
Mesencephalon9.32 ± 0.42
Myelencephalon9.22 ± 0.45
Occipital Lobe9.35 ± 0.55
Parietal Lobe9.09 ± 0.45
Pontine Tegmentum9.25 ± 0.41
Striatum9.64 ± 0.5
Subthalamus9.14 ± 0.27
Temporal Lobe8.95 ± 0.32
Thalamus9.38 ± 0.28
White Matter10.84 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wasf2CBCerebellum59.72
83.63
Wasf2CTXCerebral cortex91.23
70.1
Wasf2HIPHippocampal region34.32
36.34
Wasf2HPFHippocampal formation42.13
39.6
Wasf2HYHypothalamus13.42
10.3
Wasf2LSXLateral septal complex12.16
7.67
Wasf2MBMidbrain23.8
19.64
Wasf2MYMedulla27.27
25.54
Wasf2OLFOlfactory bulb67.37
55.66
Wasf2PPons20.91
19.23
Wasf2PALPallidum13.46
10.15
Wasf2RHPRetrohippocampal region56.3
45.04
Wasf2sAMYStriatum-like amygdalar nuclei23.37
15.29
Wasf2STRStriatum25.34
16.78
Wasf2STRdStriatum dorsal region26.58
17.77
Wasf2STRvStriatum ventral region28.57
18.4
Wasf2THThalamus11.69
8.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007058 16 23 38 SELECVTNITLANVIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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