AutismKB 2.0

Annotation Detail for SLC25A15


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Basic Information Top
Gene Symbol:SLC25A15 ( D13S327,HHH,ORC1,ORNT1 )
Gene Full Name: solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
Band: 13q14.11
Quick LinksEntrez ID:10166; OMIM: 603861; Uniprot ID:ORNT1_HUMAN; ENSEMBL ID: ENSG00000102743; HGNC ID: 10985
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus26 / 56401246
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor7 / 26384526
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor9 / 9635993
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal77 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain12 / 110098910
cervix3 / 4817162
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye8 / 21105437
heart6 / 8962666
intestine6 / 23447225
kidney8 / 21177737
larynx0 / 241450 
liver15 / 20774372
lung6 / 33697417
lymph3 / 4427067
lymph node1 / 9161010
mammary gland9 / 15327158
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate6 / 18934531
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach3 / 9661931
testis12 / 33044236
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218653_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.05
Adipocyte3.8
AdrenalCortex3.8
Adrenalgland3.15
Amygdala4.15
Appendix4.65
AtrioventricularNode2.8
BDCA4+_DentriticCells4.35
Bonemarrow9.1
BronchialEpithelialCells7.35
CD105+_Endothelial157.75
CD14+_Monocytes3.45
CD19+_BCells(neg._sel.)5
CD33+_Myeloid5
CD34+150
CD4+_Tcells6.9
CD56+_NKCells7.7
CD71+_EarlyErythroid12.95
CD8+_Tcells7.15
CardiacMyocytes5.15
Caudatenucleus3.3
Cerebellum3.1
CerebellumPeduncles4.35
CiliaryGanglion2.65
CingulateCortex3.9
Colorectaladenocarcinoma12.6
DorsalRootGanglion2.85
FetalThyroid7.35
Fetalbrain4.15
Fetalliver13.35
Fetallung24.95
GlobusPallidus2.7
Heart4.7
Hypothalamus4.5
Kidney3
Leukemia_chronicMyelogenousK-5627.25
Leukemia_promyelocytic-HL-6030.95
Leukemialymphoblastic(MOLT-4)10.8
Liver151.85
Lung4.3
Lymphnode4.6
Lymphoma_burkitts(Daudi)28.9
Lymphoma_burkitts(Raji)21.85
MedullaOblongata3.5
OccipitalLobe3.4
OlfactoryBulb4.15
Ovary2.5
Pancreas6.55
PancreaticIslet4.05
ParietalLobe3.9
Pituitary4.45
Placenta4
Pons3.65
PrefrontalCortex4.25
Prostate4.45
Salivarygland3
SkeletalMuscle4.3
Skin2.95
SmoothMuscle4.4
Spinalcord4.1
SubthalamicNucleus3.5
SuperiorCervicalGanglion4.2
TemporalLobe3.45
Testis15.9
TestisGermCell13.8
TestisIntersitial16.2
TestisLeydigCell7.35
TestisSeminiferousTubule9.55
Thalamus3.75
Thymus3.55
Thyroid166.55
Tongue3.65
Tonsil3.75
Trachea3.15
TrigeminalGanglion3.9
Uterus3.15
UterusCorpus3.35
WholeBlood6.55
Wholebrain6.4
colon3.95
pineal_day4.64
pineal_night4.6
retina5.55
small_intestine68.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P128650
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.39 ± 0.49
Basal Forebrain6.09 ± 0.34
Basal Part of Pons5.85 ± 0.28
Cerebellar Cortex5.36 ± 0.38
Cerebellar Nuclei6.11 ± 0.4
Claustrum4.79 ± 0.59
Epithalamus5.43 ± 0.45
Frontal Lobe5.7 ± 0.4
Globus Pallidus6.11 ± 0.2
Hypothalamus5.7 ± 0.4
Insula5.63 ± 0.35
Limbic Lobe5.43 ± 0.4
Mesencephalon5.61 ± 0.56
Myelencephalon5.61 ± 0.48
Occipital Lobe5.66 ± 0.46
Parietal Lobe5.69 ± 0.44
Pontine Tegmentum5.6 ± 0.48
Striatum5.98 ± 0.39
Subthalamus6.42 ± 0.08
Temporal Lobe5.43 ± 0.36
Thalamus5.7 ± 0.38
White Matter4.55 ± 0.55
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc25a15CBCerebellum1.95
2.9
Slc25a15CTXCerebral cortex1.49
1.22
Slc25a15HIPHippocampal region0.76
0.97
Slc25a15HPFHippocampal formation0.59
0.71
Slc25a15HYHypothalamus1.39
2
Slc25a15LSXLateral septal complex1.75
1.23
Slc25a15MBMidbrain1.47
1.71
Slc25a15MYMedulla3.11
3.02
Slc25a15OLFOlfactory bulb3.78
2.94
Slc25a15PPons1.52
2.25
Slc25a15PALPallidum1.34
1.34
Slc25a15RHPRetrohippocampal region0.2
0.26
Slc25a15sAMYStriatum-like amygdalar nuclei0.1
0.3
Slc25a15STRStriatum1.17
0.8
Slc25a15STRdStriatum dorsal region0.2
0.18
Slc25a15STRvStriatum ventral region3.9
2.33
Slc25a15THThalamus1.31
1.44
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00074056 28 104 131 LSDLQNAAAGSFASAFAALVLCPTELVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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