AutismKB 2.0

Annotation Detail for DHRS9


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Basic Information Top
Gene Symbol:DHRS9 ( 3ALPHA-HSD,RDH15,RDHL,RDHTBE,RETSDR8,SDR9C4 )
Gene Full Name: dehydrogenase/reductase (SDR family) member 9
Band: 2q31.1
Quick LinksEntrez ID:10170; OMIM: 612131; Uniprot ID:DHRS9_HUMAN; ENSEMBL ID: ENSG00000073737; HGNC ID: 16888
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal54 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain5 / 11009894
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine19 / 23447281
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph0 / 442700 
lymph node8 / 9161087
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219799_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.1
Adipocyte7.2
AdrenalCortex9.15
Adrenalgland6.5
Amygdala7.8
Appendix13.3
AtrioventricularNode8.6
BDCA4+_DentriticCells8
Bonemarrow9
BronchialEpithelialCells6.7
CD105+_Endothelial7.1
CD14+_Monocytes7.9
CD19+_BCells(neg._sel.)8.05
CD33+_Myeloid13.7
CD34+9.1
CD4+_Tcells7.15
CD56+_NKCells8.1
CD71+_EarlyErythroid7.05
CD8+_Tcells6.2
CardiacMyocytes40.6
Caudatenucleus6.65
Cerebellum6.1
CerebellumPeduncles8.95
CiliaryGanglion7.1
CingulateCortex7.75
Colorectaladenocarcinoma7.4
DorsalRootGanglion9.7
FetalThyroid10.15
Fetalbrain7.4
Fetalliver6.5
Fetallung6.45
GlobusPallidus6.6
Heart10.7
Hypothalamus7.95
Kidney6.3
Leukemia_chronicMyelogenousK-5627
Leukemia_promyelocytic-HL-606.05
Leukemialymphoblastic(MOLT-4)5.35
Liver10.7
Lung8
Lymphnode10.45
Lymphoma_burkitts(Daudi)9.45
Lymphoma_burkitts(Raji)11.05
MedullaOblongata6.95
OccipitalLobe6.6
OlfactoryBulb5.8
Ovary5.5
Pancreas5.8
PancreaticIslet7.8
ParietalLobe8.25
Pituitary10.85
Placenta7.95
Pons7.3
PrefrontalCortex9
Prostate8.7
Salivarygland6
SkeletalMuscle10.8
Skin8
SmoothMuscle7.9
Spinalcord8.2
SubthalamicNucleus6.85
SuperiorCervicalGanglion17.2
TemporalLobe7
Testis8.7
TestisGermCell6.25
TestisIntersitial7.6
TestisLeydigCell9.1
TestisSeminiferousTubule7.4
Thalamus7.55
Thymus5.8
Thyroid8.15
Tongue10
Tonsil13.25
Trachea37.7
TrigeminalGanglion11.45
Uterus6.05
UterusCorpus10.6
WholeBlood24.1
Wholebrain6.3
colon19.7
pineal_day8.12
pineal_night7.9
retina9.4
small_intestine7.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8667_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.78 ± 1
Basal Forebrain2.42 ± 0.65
Basal Part of Pons2.32 ± 0.46
Cerebellar Cortex2.11 ± 0.62
Cerebellar Nuclei3.34 ± 0.67
Claustrum3.15 ± 0.78
Epithalamus2.4 ± 0.71
Frontal Lobe2.43 ± 0.69
Globus Pallidus4.1 ± 0.39
Hypothalamus2.4 ± 0.87
Insula2.49 ± 0.91
Limbic Lobe2.53 ± 0.72
Mesencephalon2.67 ± 0.79
Myelencephalon2.56 ± 0.77
Occipital Lobe2.43 ± 0.94
Parietal Lobe2.4 ± 0.78
Pontine Tegmentum2.5 ± 0.72
Striatum2.66 ± 0.68
Subthalamus2.97 ± 0.47
Temporal Lobe2.41 ± 0.76
Thalamus2.44 ± 0.68
White Matter3.53 ± 0.87
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dhrs9CBCerebellum0.5
0.96
Dhrs9CTXCerebral cortex0.56
0.93
Dhrs9HIPHippocampal region0.12
0.16
Dhrs9HPFHippocampal formation0.14
0.14
Dhrs9HYHypothalamus0.04
0.04
Dhrs9LSXLateral septal complex0
0
Dhrs9MBMidbrain0.11
0.19
Dhrs9MYMedulla0.6
0.76
Dhrs9OLFOlfactory bulb0.41
1.59
Dhrs9PPons0.33
0.85
Dhrs9PALPallidum0.08
0.14
Dhrs9RHPRetrohippocampal region0.15
0.08
Dhrs9sAMYStriatum-like amygdalar nuclei0.12
0.09
Dhrs9STRStriatum0.81
1.4
Dhrs9STRdStriatum dorsal region1.2
2.18
Dhrs9STRvStriatum ventral region0.11
0.07
Dhrs9THThalamus0.12
0.29
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00804105 20 289 308 IFWIPLSHMPAALQDFLLLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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