AutismKB 2.0

Annotation Detail for RCL1


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Basic Information Top
Gene Symbol:RCL1 ( RNAC,RPCL1 )
Gene Full Name: RNA terminal phosphate cyclase-like 1
Band: 9p24.1
Quick LinksEntrez ID:10171; OMIM: 611405; Uniprot ID:RCL1_HUMAN; ENSEMBL ID: ENSG00000120158; HGNC ID: 17687
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus48 / 56401285
neonate1 / 3109732
infant1 / 2362042
juvenile4 / 5555671
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor13 / 26384549
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor6 / 9635962
lung tumor6 / 10312758
lymphoma9 / 71755125
non-neoplasia6 / 9725061
normal135 / 336030740
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder1 / 2975733
blood14 / 123478113
bone3 / 7165541
bone marrow6 / 48801122
brain29 / 110098926
cervix5 / 48171103
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine7 / 23447229
kidney6 / 21177728
larynx2 / 2414582
liver17 / 20774381
lung8 / 33697423
lymph4 / 4427090
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary2 / 10205119
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta8 / 28082528
prostate4 / 18934521
salivary gland0 / 201550 
skin6 / 21057428
spleen3 / 5395255
stomach3 / 9661931
testis11 / 33044233
thymus0 / 811310 
thyroid2 / 4747342
tonsil4 / 16999235
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218544_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts30.35
Adipocyte9.9
AdrenalCortex10.5
Adrenalgland8.45
Amygdala7.45
Appendix10.15
AtrioventricularNode12.2
BDCA4+_DentriticCells15.35
Bonemarrow14.35
BronchialEpithelialCells14.4
CD105+_Endothelial177.9
CD14+_Monocytes15
CD19+_BCells(neg._sel.)15.4
CD33+_Myeloid15.35
CD34+27.5
CD4+_Tcells11.3
CD56+_NKCells14.55
CD71+_EarlyErythroid305.95
CD8+_Tcells13.7
CardiacMyocytes7.85
Caudatenucleus8.95
Cerebellum8.05
CerebellumPeduncles9.55
CiliaryGanglion7.1
CingulateCortex10.2
Colorectaladenocarcinoma10
DorsalRootGanglion10
FetalThyroid11.15
Fetalbrain8.25
Fetalliver19.1
Fetallung8.25
GlobusPallidus7.4
Heart11.15
Hypothalamus10.8
Kidney8.1
Leukemia_chronicMyelogenousK-5629
Leukemia_promyelocytic-HL-6010.75
Leukemialymphoblastic(MOLT-4)8
Liver17.2
Lung10.9
Lymphnode10.75
Lymphoma_burkitts(Daudi)22.35
Lymphoma_burkitts(Raji)14.1
MedullaOblongata8.45
OccipitalLobe7.8
OlfactoryBulb7.85
Ovary6.6
Pancreas8.05
PancreaticIslet10.65
ParietalLobe8.75
Pituitary11.6
Placenta10.25
Pons10.5
PrefrontalCortex12.35
Prostate5.7
Salivarygland9.15
SkeletalMuscle11.65
Skin15.25
SmoothMuscle10.05
Spinalcord10.65
SubthalamicNucleus9.15
SuperiorCervicalGanglion11.35
TemporalLobe9.1
Testis8.85
TestisGermCell7.85
TestisIntersitial8.05
TestisLeydigCell9.55
TestisSeminiferousTubule8.5
Thalamus10.15
Thymus7.8
Thyroid9.35
Tongue9.75
Tonsil9.65
Trachea8.35
TrigeminalGanglion10.05
Uterus6.55
UterusCorpus9
WholeBlood7
Wholebrain8.2
colon11.9
pineal_day11.78
pineal_night12.08
retina15.975
small_intestine11.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1915_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.2 ± 0.67
Basal Forebrain3.94 ± 0.35
Basal Part of Pons3.92 ± 0.48
Cerebellar Cortex4.11 ± 0.36
Cerebellar Nuclei3.86 ± 0.48
Claustrum3.89 ± 0.58
Epithalamus4.6 ± 0.44
Frontal Lobe3.86 ± 0.54
Globus Pallidus4.75 ± 0.54
Hypothalamus3.9 ± 0.56
Insula3.89 ± 0.51
Limbic Lobe3.85 ± 0.6
Mesencephalon4.13 ± 0.59
Myelencephalon3.99 ± 0.54
Occipital Lobe4.33 ± 0.58
Parietal Lobe3.95 ± 0.48
Pontine Tegmentum3.99 ± 0.58
Striatum4.2 ± 0.58
Subthalamus4.06 ± 0.19
Temporal Lobe3.8 ± 0.52
Thalamus3.97 ± 0.5
White Matter5.4 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rcl1CBCerebellum11.03
11.99
Rcl1CTXCerebral cortex20.53
14.38
Rcl1HIPHippocampal region28.56
35.27
Rcl1HPFHippocampal formation30.05
30.33
Rcl1HYHypothalamus13.77
10.99
Rcl1LSXLateral septal complex11.33
8.51
Rcl1MBMidbrain14.52
12.63
Rcl1MYMedulla21.69
24.87
Rcl1OLFOlfactory bulb27.98
22.01
Rcl1PPons17.52
18.05
Rcl1PALPallidum12.67
11.22
Rcl1RHPRetrohippocampal region32.52
23.96
Rcl1sAMYStriatum-like amygdalar nuclei33.14
24.33
Rcl1STRStriatum14.01
10
Rcl1STRdStriatum dorsal region12.93
9.24
Rcl1STRvStriatum ventral region11.74
7.81
Rcl1THThalamus11.36
10.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00069113 15 119 133 GVTNDQVDPSVDVLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018