AutismKB 2.0

Annotation Detail for CNIH


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Basic Information Top
Gene Symbol:CNIH ( CNIH1,CNIL,MGC117156,TGAM77 )
Gene Full Name: cornichon homolog (Drosophila)
Band: 14q22.2
Quick LinksEntrez ID:10175; OMIM: 611287; Uniprot ID:CNIH_HUMAN; ENSEMBL ID: ENSG00000100528; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201653_at
Cell line Expression level Expression bar
721_B_lymphoblasts250.85
Adipocyte189.6
AdrenalCortex15.35
Adrenalgland55
Amygdala144.2
Appendix34.35
AtrioventricularNode6.9
BDCA4+_DentriticCells176.1
Bonemarrow54.95
BronchialEpithelialCells428.25
CD105+_Endothelial137.6
CD14+_Monocytes278.9
CD19+_BCells(neg._sel.)192.55
CD33+_Myeloid435.65
CD34+159.45
CD4+_Tcells45.75
CD56+_NKCells86.65
CD71+_EarlyErythroid24.15
CD8+_Tcells57
CardiacMyocytes158.3
Caudatenucleus48.8
Cerebellum40.8
CerebellumPeduncles35.25
CiliaryGanglion12.9
CingulateCortex24.65
Colorectaladenocarcinoma92.6
DorsalRootGanglion8.9
FetalThyroid32.4
Fetalbrain81.35
Fetalliver153.15
Fetallung97.05
GlobusPallidus21.75
Heart69.75
Hypothalamus49.95
Kidney30.95
Leukemia_chronicMyelogenousK-56256.8
Leukemia_promyelocytic-HL-60261.6
Leukemialymphoblastic(MOLT-4)142.3
Liver232.2
Lung115.7
Lymphnode71.4
Lymphoma_burkitts(Daudi)364.5
Lymphoma_burkitts(Raji)246.85
MedullaOblongata21.9
OccipitalLobe35.45
OlfactoryBulb34.1
Ovary14.4
Pancreas27.4
PancreaticIslet67.5
ParietalLobe13.45
Pituitary136.05
Placenta55.85
Pons21.2
PrefrontalCortex72.05
Prostate148.4
Salivarygland56.65
SkeletalMuscle8.1
Skin9.65
SmoothMuscle311.15
Spinalcord87.75
SubthalamicNucleus26.65
SuperiorCervicalGanglion9.75
TemporalLobe22.3
Testis73.15
TestisGermCell53.85
TestisIntersitial19.25
TestisLeydigCell14.1
TestisSeminiferousTubule28.95
Thalamus50.55
Thymus59.25
Thyroid198.95
Tongue12.75
Tonsil53.6
Trachea62
TrigeminalGanglion24.95
Uterus129.5
UterusCorpus25.65
WholeBlood135.4
Wholebrain140.55
colon310.9
pineal_day161.12
pineal_night131.72
retina152.025
small_intestine417.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1675_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.42 ± 0.34
Basal Forebrain6.42 ± 0.16
Basal Part of Pons6.88 ± 0.1
Cerebellar Cortex6.64 ± 0.23
Cerebellar Nuclei6.7 ± 0.25
Claustrum6.55 ± 0.23
Epithalamus6.56 ± 0.49
Frontal Lobe6.58 ± 0.31
Globus Pallidus6.64 ± 0.26
Hypothalamus6.69 ± 0.26
Insula6.62 ± 0.26
Limbic Lobe6.38 ± 0.33
Mesencephalon6.49 ± 0.32
Myelencephalon6.48 ± 0.35
Occipital Lobe6.5 ± 0.29
Parietal Lobe6.57 ± 0.31
Pontine Tegmentum6.55 ± 0.33
Striatum6.27 ± 0.27
Subthalamus6.92 ± 0.47
Temporal Lobe6.54 ± 0.33
Thalamus6.46 ± 0.33
White Matter7.1 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CnihCBCerebellum75.05
77.34
CnihCTXCerebral cortex93.81
84.7
CnihHIPHippocampal region78.04
89.08
CnihHPFHippocampal formation89.86
91.24
CnihHYHypothalamus76.88
71.69
CnihLSXLateral septal complex88.79
76.1
CnihMBMidbrain78.81
78.82
CnihMYMedulla85.19
94.05
CnihOLFOlfactory bulb100
95.05
CnihPPons82.78
91.04
CnihPALPallidum78.33
76.41
CnihRHPRetrohippocampal region98.7
94.11
CnihsAMYStriatum-like amygdalar nuclei81.23
70.86
CnihSTRStriatum78.3
66.05
CnihSTRdStriatum dorsal region73.23
60.01
CnihSTRvStriatum ventral region92.05
77.81
CnihTHThalamus70.22
69.83
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009004 29 89 117 YMSRPVMSGPGLYDPTTIMNADILAYCQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018