AutismKB 2.0

Annotation Detail for LHFPL2


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Basic Information Top
Gene Symbol:LHFPL2 ( DKFZp781E0375,KIAA0206 )
Gene Full Name: lipoma HMGIC fusion partner-like 2
Band: 5q14.1
Quick LinksEntrez ID:10184; OMIM: 609718; Uniprot ID:LHPL2_HUMAN; ENSEMBL ID: ENSG00000145685; HGNC ID: 6588
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst2 / 6231932
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult52 / 193912126
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor11 / 26384541
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal120 / 336030735
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal2 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone9 / 71655125
bone marrow1 / 4880120
brain27 / 110098924
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus1 / 2020949
eye6 / 21105428
heart10 / 89626111
intestine6 / 23447225
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung8 / 33697423
lymph0 / 442700 
lymph node12 / 91610130
mammary gland7 / 15327145
mouth2 / 6705229
muscle2 / 10771518
nerve4 / 15768253
ovary1 / 1020519
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate4 / 18934521
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach2 / 9661920
testis8 / 33044224
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular3 / 5178057
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212658_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.75
Adipocyte70.15
AdrenalCortex68.1
Adrenalgland67.6
Amygdala34.95
Appendix38.65
AtrioventricularNode47.15
BDCA4+_DentriticCells291.5
Bonemarrow26.95
BronchialEpithelialCells43.4
CD105+_Endothelial53.75
CD14+_Monocytes44.35
CD19+_BCells(neg._sel.)41.3
CD33+_Myeloid51.35
CD34+58.7
CD4+_Tcells12.75
CD56+_NKCells14.4
CD71+_EarlyErythroid31.3
CD8+_Tcells10.45
CardiacMyocytes74.8
Caudatenucleus39.8
Cerebellum25
CerebellumPeduncles49.25
CiliaryGanglion73.95
CingulateCortex45.25
Colorectaladenocarcinoma23.85
DorsalRootGanglion99
FetalThyroid37
Fetalbrain43.9
Fetalliver24.15
Fetallung89.75
GlobusPallidus28.6
Heart20.55
Hypothalamus70.55
Kidney22.7
Leukemia_chronicMyelogenousK-56225.15
Leukemia_promyelocytic-HL-60114.8
Leukemialymphoblastic(MOLT-4)17.15
Liver46.05
Lung74.6
Lymphnode55.25
Lymphoma_burkitts(Daudi)64.8
Lymphoma_burkitts(Raji)61.95
MedullaOblongata35.35
OccipitalLobe31.3
OlfactoryBulb80
Ovary48.95
Pancreas38.45
PancreaticIslet47.55
ParietalLobe29.95
Pituitary49.85
Placenta108.3
Pons27.25
PrefrontalCortex50.35
Prostate40.5
Salivarygland82.15
SkeletalMuscle32.85
Skin52.85
SmoothMuscle205.3
Spinalcord62.2
SubthalamicNucleus25.4
SuperiorCervicalGanglion38.4
TemporalLobe37.15
Testis49.85
TestisGermCell83.5
TestisIntersitial47.7
TestisLeydigCell38.6
TestisSeminiferousTubule52.9
Thalamus45.05
Thymus43.65
Thyroid46.6
Tongue42.9
Tonsil76.7
Trachea73.35
TrigeminalGanglion47.7
Uterus52.85
UterusCorpus86.55
WholeBlood38.65
Wholebrain29.5
colon47.65
pineal_day23.1
pineal_night18.58
retina57.65
small_intestine48.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P349092
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.14 ± 0.86
Basal Forebrain2.84 ± 0.57
Basal Part of Pons2.92 ± 0.39
Cerebellar Cortex2.73 ± 0.54
Cerebellar Nuclei3.63 ± 0.58
Claustrum3.12 ± 0.59
Epithalamus3.6 ± 0.48
Frontal Lobe3.19 ± 0.6
Globus Pallidus4.08 ± 0.61
Hypothalamus3.03 ± 0.5
Insula3.29 ± 0.65
Limbic Lobe3.23 ± 0.61
Mesencephalon3.27 ± 0.8
Myelencephalon3.27 ± 0.66
Occipital Lobe3.34 ± 0.74
Parietal Lobe3.26 ± 0.63
Pontine Tegmentum3.25 ± 0.73
Striatum3.65 ± 0.47
Subthalamus3.54 ± 0.25
Temporal Lobe3.21 ± 0.68
Thalamus3.23 ± 0.62
White Matter2.91 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lhfpl2CBCerebellum1.89
2.13
Lhfpl2CTXCerebral cortex1.25
0.88
Lhfpl2HIPHippocampal region9.1
9.76
Lhfpl2HPFHippocampal formation5.62
5.46
Lhfpl2HYHypothalamus0.5
0.36
Lhfpl2LSXLateral septal complex0.83
0.57
Lhfpl2MBMidbrain1.63
1.54
Lhfpl2MYMedulla1.61
1.94
Lhfpl2OLFOlfactory bulb1.81
1.33
Lhfpl2PPons0.56
0.46
Lhfpl2PALPallidum0.52
0.31
Lhfpl2RHPRetrohippocampal region1.08
0.84
Lhfpl2sAMYStriatum-like amygdalar nuclei0.59
0.82
Lhfpl2STRStriatum0.64
0.52
Lhfpl2STRdStriatum dorsal region0.67
0.57
Lhfpl2STRvStriatum ventral region0.51
0.28
Lhfpl2THThalamus2.76
2.27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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