AutismKB 2.0

Annotation Detail for TSHZ1


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Basic Information Top
Gene Symbol:TSHZ1 ( NY-CO-33,SDCCAG33,TSH1 )
Gene Full Name: teashirt zinc finger homeobox 1
Band: 18q22.3
Quick LinksEntrez ID:10194; OMIM: NA; Uniprot ID:TSH1_HUMAN; ENSEMBL ID: ENSG00000179981; HGNC ID: 10669
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor10 / 26384537
glioma11 / 106883102
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal91 / 336030727
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain33 / 110098929
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye6 / 21105428
heart6 / 8962666
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung16 / 33697447
lymph0 / 442700 
lymph node7 / 9161076
mammary gland5 / 15327132
mouth2 / 6705229
muscle2 / 10771518
nerve2 / 15768126
ovary5 / 10205148
pancreas11 / 21481251
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta6 / 28082521
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach3 / 9661931
testis3 / 3304429
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10171_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.97 ± 1.16
Basal Forebrain2.46 ± 0.24
Basal Part of Pons2.17 ± 0.55
Cerebellar Cortex2.77 ± 0.83
Cerebellar Nuclei2.85 ± 0.81
Claustrum3.26 ± 0.72
Epithalamus2.23 ± 0.8
Frontal Lobe2.35 ± 0.65
Globus Pallidus2.76 ± 0.43
Hypothalamus2.53 ± 0.73
Insula2.38 ± 0.64
Limbic Lobe2.53 ± 0.78
Mesencephalon2.71 ± 0.77
Myelencephalon2.61 ± 0.67
Occipital Lobe2.92 ± 1.04
Parietal Lobe2.56 ± 0.76
Pontine Tegmentum2.6 ± 0.7
Striatum2.57 ± 0.87
Subthalamus2.62 ± 0.69
Temporal Lobe2.45 ± 0.64
Thalamus2.52 ± 0.7
White Matter2.88 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tshz1CBCerebellum72.29
78.19
Tshz1CTXCerebral cortex84.2
79.18
Tshz1HIPHippocampal region74.27
95.93
Tshz1HPFHippocampal formation78.41
86.52
Tshz1HYHypothalamus60.75
57.01
Tshz1LSXLateral septal complex47.39
45.18
Tshz1MBMidbrain73.5
72.47
Tshz1MYMedulla81.37
90.62
Tshz1OLFOlfactory bulb87.38
99.54
Tshz1PPons71.87
77.46
Tshz1PALPallidum60.38
65.75
Tshz1RHPRetrohippocampal region77.8
76.01
Tshz1sAMYStriatum-like amygdalar nuclei84.03
88.18
Tshz1STRStriatum76.69
77.04
Tshz1STRdStriatum dorsal region72.87
70.87
Tshz1STRvStriatum ventral region91.33
93.23
Tshz1THThalamus89.6
89.13
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018