AutismKB 2.0

Annotation Detail for CALCRL


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Basic Information Top
Gene Symbol:CALCRL ( CGRPR,CRLR )
Gene Full Name: calcitonin receptor-like
Band: 2q32.1
Quick LinksEntrez ID:10203; OMIM: 114190; Uniprot ID:CALRL_HUMAN; ENSEMBL ID: ENSG00000064989; HGNC ID: 16709
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia12 / 97250123
normal85 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow2 / 4880140
brain23 / 110098920
cervix1 / 4817120
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye1 / 2110544
heart3 / 8962633
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung20 / 33697459
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth6 / 6705289
muscle9 / 10771583
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach2 / 9661920
testis8 / 33044224
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea17 / 52413324
umbilical cord0 / 136800 
uterus14 / 23287860
vascular10 / 51780193
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206331_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte5.3
AdrenalCortex6.2
Adrenalgland4.95
Amygdala5.25
Appendix6.75
AtrioventricularNode6.1
BDCA4+_DentriticCells5.4
Bonemarrow6.2
BronchialEpithelialCells4.85
CD105+_Endothelial5.05
CD14+_Monocytes5.55
CD19+_BCells(neg._sel.)5.2
CD33+_Myeloid6.7
CD34+6.4
CD4+_Tcells5.25
CD56+_NKCells6
CD71+_EarlyErythroid4.85
CD8+_Tcells4.35
CardiacMyocytes7.25
Caudatenucleus4.85
Cerebellum4.35
CerebellumPeduncles6.15
CiliaryGanglion4.6
CingulateCortex5.5
Colorectaladenocarcinoma5.2
DorsalRootGanglion5.05
FetalThyroid6.2
Fetalbrain5.2
Fetalliver5.6
Fetallung42.7
GlobusPallidus4.05
Heart8.15
Hypothalamus5.55
Kidney4.95
Leukemia_chronicMyelogenousK-5624.8
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.1
Liver7.6
Lung5.8
Lymphnode5.6
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)7.65
MedullaOblongata4.85
OccipitalLobe4.6
OlfactoryBulb4.2
Ovary4.9
Pancreas4.25
PancreaticIslet5.7
ParietalLobe5.8
Pituitary6.15
Placenta5.25
Pons5.15
PrefrontalCortex6.45
Prostate6.1
Salivarygland7.95
SkeletalMuscle7.4
Skin4.55
SmoothMuscle6
Spinalcord6.45
SubthalamicNucleus4.95
SuperiorCervicalGanglion9.9
TemporalLobe4.95
Testis4.6
TestisGermCell4.4
TestisIntersitial4.55
TestisLeydigCell5.3
TestisSeminiferousTubule4.65
Thalamus6.25
Thymus3.8
Thyroid9.4
Tongue5.55
Tonsil5.2
Trachea4.95
TrigeminalGanglion6
Uterus8.8
UterusCorpus6.55
WholeBlood5.55
Wholebrain4.35
colon5.25
pineal_day6.22
pineal_night6.06
retina6.4
small_intestine5.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14234_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.77 ± 0.76
Basal Forebrain6.3 ± 0.5
Basal Part of Pons5.3 ± 0.29
Cerebellar Cortex5.51 ± 0.55
Cerebellar Nuclei6.19 ± 0.5
Claustrum5 ± 0.8
Epithalamus5.52 ± 0.8
Frontal Lobe5.68 ± 0.57
Globus Pallidus6.28 ± 0.45
Hypothalamus6.05 ± 0.45
Insula5.85 ± 0.5
Limbic Lobe5.59 ± 0.74
Mesencephalon5.64 ± 0.65
Myelencephalon5.98 ± 0.49
Occipital Lobe5.69 ± 0.6
Parietal Lobe5.61 ± 0.48
Pontine Tegmentum5.91 ± 0.46
Striatum6.25 ± 0.52
Subthalamus5.36 ± 0.57
Temporal Lobe5.76 ± 0.41
Thalamus5.8 ± 0.46
White Matter6.1 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CalcrlCBCerebellum0.17
0.75
CalcrlCTXCerebral cortex0.22
0.28
CalcrlHIPHippocampal region0.15
0.16
CalcrlHPFHippocampal formation0.13
0.13
CalcrlHYHypothalamus0.24
0.18
CalcrlLSXLateral septal complex0
0
CalcrlMBMidbrain0.52
0.58
CalcrlMYMedulla0.14
0.21
CalcrlOLFOlfactory bulb0.65
1.36
CalcrlPPons0.07
0.08
CalcrlPALPallidum0.03
0.03
CalcrlRHPRetrohippocampal region0.1
0.1
CalcrlsAMYStriatum-like amygdalar nuclei0.07
0.06
CalcrlSTRStriatum0.17
0.19
CalcrlSTRdStriatum dorsal region0.21
0.25
CalcrlSTRvStriatum ventral region0.26
0.23
CalcrlTHThalamus0.11
0.21
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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