Annotation Detail for TRIB1
Basic Information Top
| Gene Symbol: | TRIB1 ( C8FW,GIG2,SKIP1,TRB1 ) |
|---|---|
| Gene Full Name: | tribbles homolog 1 (Drosophila) |
| Band: | 8q24.13 |
| Quick Links | Entrez ID:10221; OMIM: 609461; Uniprot ID:TRIB1_HUMAN; ENSEMBL ID: ENSG00000173334; HGNC ID: 16891 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.444947
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 39 / 564012 | 69 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 104 / 1939121 | 53 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 8 / 94178 | 84 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 7 / 114246 | 61 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 21 / 263845 | 79 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 12 / 136302 | 88 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 8 / 95842 | 83 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 130 / 3360307 | 38 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 6 / 123478 | 48 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 17 / 1100989 | 15 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 10 / 211054 | 47 | |
| heart | 1 / 89626 | 11 | |
| intestine | 25 / 234472 | 106 | |
| kidney | 23 / 211777 | 108 | |
| larynx | 0 / 24145 | 0 | |
| liver | 10 / 207743 | 48 | |
| lung | 34 / 336974 | 100 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 16 / 153271 | 104 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 7 / 210574 | 33 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 3 / 96619 | 31 | |
| testis | 6 / 330442 | 18 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 11 / 47473 | 231 |  |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 13 / 232878 | 55 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202241_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 18.5 | |
| Adipocyte | 5 | |
| AdrenalCortex | 42.55 | |
| Adrenalgland | 6.05 | |
| Amygdala | 14.6 | |
| Appendix | 5.15 | |
| AtrioventricularNode | 3.95 | |
| BDCA4+_DentriticCells | 179.2 | |
| Bonemarrow | 117.5 | |
| BronchialEpithelialCells | 38.9 | |
| CD105+_Endothelial | 8.85 | |
| CD14+_Monocytes | 221.3 | |
| CD19+_BCells(neg._sel.) | 10.7 | |
| CD33+_Myeloid | 958.25 | |
| CD34+ | 19.25 | |
| CD4+_Tcells | 5.1 | |
| CD56+_NKCells | 35.65 | |
| CD71+_EarlyErythroid | 4.9 | |
| CD8+_Tcells | 4.45 | |
| CardiacMyocytes | 6.85 | |
| Caudatenucleus | 5.3 | |
| Cerebellum | 7.1 | |
| CerebellumPeduncles | 7.7 | |
| CiliaryGanglion | 18.5 | |
| CingulateCortex | 6.85 | |
| Colorectaladenocarcinoma | 239.5 | |
| DorsalRootGanglion | 4.1 | |
| FetalThyroid | 265.9 | |
| Fetalbrain | 7.55 | |
| Fetalliver | 13.55 | |
| Fetallung | 44.7 | |
| GlobusPallidus | 4.15 | |
| Heart | 7.8 | |
| Hypothalamus | 8.6 | |
| Kidney | 5.9 | |
| Leukemia_chronicMyelogenousK-562 | 6.6 | |
| Leukemia_promyelocytic-HL-60 | 6.75 | |
| Leukemialymphoblastic(MOLT-4) | 3.75 | |
| Liver | 66.8 | |
| Lung | 129.5 | |
| Lymphnode | 15.55 | |
| Lymphoma_burkitts(Daudi) | 20.05 | |
| Lymphoma_burkitts(Raji) | 9 | |
| MedullaOblongata | 4.9 | |
| OccipitalLobe | 8.1 | |
| OlfactoryBulb | 4.6 | |
| Ovary | 3.15 | |
| Pancreas | 19.5 | |
| PancreaticIslet | 102.6 | |
| ParietalLobe | 5.15 | |
| Pituitary | 9.05 | |
| Placenta | 141.85 | |
| Pons | 5.4 | |
| PrefrontalCortex | 7.75 | |
| Prostate | 30.95 | |
| Salivarygland | 9 | |
| SkeletalMuscle | 8.05 | |
| Skin | 5.1 | |
| SmoothMuscle | 7.8 | |
| Spinalcord | 6.25 | |
| SubthalamicNucleus | 5.4 | |
| SuperiorCervicalGanglion | 6.05 | |
| TemporalLobe | 5.5 | |
| Testis | 10.7 | |
| TestisGermCell | 13.55 | |
| TestisIntersitial | 5.55 | |
| TestisLeydigCell | 5.8 | |
| TestisSeminiferousTubule | 6.95 | |
| Thalamus | 4.8 | |
| Thymus | 10.2 | |
| Thyroid | 495.9 | |
| Tongue | 6.15 | |
| Tonsil | 15.4 | |
| Trachea | 18.15 | |
| TrigeminalGanglion | 6.5 | |
| Uterus | 11.35 | |
| UterusCorpus | 8.5 | |
| WholeBlood | 86 | |
| Wholebrain | 23.85 | |
| colon | 60.9 | |
| pineal_day | 48 | |
| pineal_night | 53.12 | |
| retina | 86.05 | |
| small_intestine | 63.3 | |
- Probe name: A_23_P123503
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.63 ± 0.47 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.19 ± 0.37 | |
| Basal Part of Pons | 4.49 ± 0.5 | |
| Cerebellar Cortex | 4.94 ± 0.35 | |
| Cerebellar Nuclei | 4.59 ± 0.51 | |
| Claustrum | 5.42 ± 0.52 | |
| Epithalamus | 4.69 ± 0.53 | |
| Frontal Lobe | 5.01 ± 0.54 | |
| Globus Pallidus | 5.13 ± 0.29 | |
| Hypothalamus | 5.1 ± 0.62 | |
| Insula | 5.05 ± 0.61 | |
| Limbic Lobe | 5.07 ± 0.62 | |
| Mesencephalon | 5.32 ± 0.41 | |
| Myelencephalon | 5.08 ± 0.61 | |
| Occipital Lobe | 5.4 ± 0.68 | |
| Parietal Lobe | 5.02 ± 0.5 | |
| Pontine Tegmentum | 5.19 ± 0.62 | |
| Striatum | 5.83 ± 0.58 | |
| Subthalamus | 4.89 ± 0.83 | |
| Temporal Lobe | 4.92 ± 0.55 | |
| Thalamus | 5.28 ± 0.46 | |
| White Matter | 4.17 ± 0.48 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Trib1 | CB | Cerebellum | 11.42 | |
| 20.46 | | |||
| Trib1 | CTX | Cerebral cortex | 13.35 | |
| 7.11 | | |||
| Trib1 | HIP | Hippocampal region | 1.95 | |
| 1.51 | | |||
| Trib1 | HPF | Hippocampal formation | 2.41 | |
| 1.68 | | |||
| Trib1 | HY | Hypothalamus | 0.96 | |
| 0.64 | | |||
| Trib1 | LSX | Lateral septal complex | 0.55 | |
| 0.29 | | |||
| Trib1 | MB | Midbrain | 0.64 | |
| 0.55 | | |||
| Trib1 | MY | Medulla | 2.23 | |
| 2.26 | | |||
| Trib1 | OLF | Olfactory bulb | 4.24 | |
| 2.12 | | |||
| Trib1 | P | Pons | 0.62 | |
| 0.77 | | |||
| Trib1 | PAL | Pallidum | 0.23 | |
| 0.15 | | |||
| Trib1 | RHP | Retrohippocampal region | 2.83 | |
| 1.68 | | |||
| Trib1 | sAMY | Striatum-like amygdalar nuclei | 0.67 | |
| 0.44 | | |||
| Trib1 | STR | Striatum | 0.56 | |
| 0.33 | | |||
| Trib1 | STRd | Striatum dorsal region | 0.49 | |
| 0.31 | | |||
| Trib1 | STRv | Striatum ventral region | 0.58 | |
| 0.31 | | |||
| Trib1 | TH | Thalamus | 2.12 | |
| 1.34 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| TRIB1_HUMAN_101 | 7 | 101 | 107 | EREHVSR | PRIDE |