AutismKB 2.0

Annotation Detail for ZNF443


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Basic Information Top
Gene Symbol:ZNF443 ( ZK1 )
Gene Full Name: zinc finger protein 443
Band: 19p13.2
Quick LinksEntrez ID:10224; OMIM: 606697; Uniprot ID:ZN443_HUMAN; ENSEMBL ID: ENSG00000180855; HGNC ID: 20878
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus11 / 56401219
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal23 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver4 / 20774319
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen2 / 5395237
stomach0 / 966190 
testis4 / 33044212
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205928_at
Cell line Expression level Expression bar
721_B_lymphoblasts47.65
Adipocyte7.25
AdrenalCortex11.15
Adrenalgland6.4
Amygdala6.65
Appendix11.6
AtrioventricularNode9.3
BDCA4+_DentriticCells11.05
Bonemarrow7.8
BronchialEpithelialCells6.45
CD105+_Endothelial10
CD14+_Monocytes8.6
CD19+_BCells(neg._sel.)7.8
CD33+_Myeloid10
CD34+13.2
CD4+_Tcells9.7
CD56+_NKCells14.05
CD71+_EarlyErythroid7.1
CD8+_Tcells14.75
CardiacMyocytes10.2
Caudatenucleus6.9
Cerebellum5.9
CerebellumPeduncles8.75
CiliaryGanglion7.7
CingulateCortex7.7
Colorectaladenocarcinoma7.35
DorsalRootGanglion7.9
FetalThyroid7.6
Fetalbrain8.9
Fetalliver6.85
Fetallung6.1
GlobusPallidus6.45
Heart13.2
Hypothalamus7.75
Kidney6.55
Leukemia_chronicMyelogenousK-56216
Leukemia_promyelocytic-HL-606.8
Leukemialymphoblastic(MOLT-4)19.4
Liver11.05
Lung7.9
Lymphnode10.3
Lymphoma_burkitts(Daudi)11.5
Lymphoma_burkitts(Raji)11.85
MedullaOblongata7.75
OccipitalLobe6.55
OlfactoryBulb5.85
Ovary5.25
Pancreas7.5
PancreaticIslet8.4
ParietalLobe8.05
Pituitary9.35
Placenta6.6
Pons7.5
PrefrontalCortex10.85
Prostate10.35
Salivarygland7.45
SkeletalMuscle14.65
Skin10.75
SmoothMuscle8.2
Spinalcord7.55
SubthalamicNucleus7
SuperiorCervicalGanglion14.1
TemporalLobe7.25
Testis6.35
TestisGermCell6.6
TestisIntersitial6.25
TestisLeydigCell9.7
TestisSeminiferousTubule6.75
Thalamus7.75
Thymus6.35
Thyroid10.25
Tongue8.8
Tonsil7.4
Trachea6.1
TrigeminalGanglion48.5
Uterus10.75
UterusCorpus7.45
WholeBlood9.65
Wholebrain5.4
colon8.4
pineal_day9.8
pineal_night11.84
retina8.675
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6005_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.23 ± 0.97
Basal Forebrain2.8 ± 0.35
Basal Part of Pons2.73 ± 0.5
Cerebellar Cortex2.6 ± 0.72
Cerebellar Nuclei3.3 ± 0.76
Claustrum3.38 ± 0.84
Epithalamus3.39 ± 0.69
Frontal Lobe2.82 ± 0.75
Globus Pallidus3.69 ± 0.43
Hypothalamus2.63 ± 0.83
Insula2.7 ± 0.4
Limbic Lobe2.93 ± 0.58
Mesencephalon3.04 ± 0.65
Myelencephalon2.94 ± 0.71
Occipital Lobe3.1 ± 0.85
Parietal Lobe3.05 ± 0.75
Pontine Tegmentum3.06 ± 0.75
Striatum3.4 ± 0.58
Subthalamus3.32 ± 0.06
Temporal Lobe2.78 ± 0.7
Thalamus2.9 ± 0.62
White Matter3.31 ± 1.1
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018