AutismKB 2.0

Annotation Detail for HNRNPR


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Basic Information Top
Gene Symbol:HNRNPR ( FLJ25714,HNRPR,hnRNP R,hnRNP-R )
Gene Full Name: heterogeneous nuclear ribonucleoprotein R
Band: 1p36.12
Quick LinksEntrez ID:10236; OMIM: 607201; Uniprot ID:HNRPR_HUMAN; ENSEMBL ID: ENSG00000125944; HGNC ID: 5047
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body19 / 70761268
blastocyst10 / 62319160
fetus140 / 564012248
neonate16 / 31097514
infant8 / 23620338
juvenile33 / 55556593
adult282 / 1939121145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma3 / 17475171
breast (mammary gland) tumor17 / 94178180
cervical tumor11 / 34366320
chondrosarcoma12 / 82823144
colorectal tumor10 / 11424687
esophageal tumor7 / 17290404
gastrointestinal tumor16 / 119369134
germ cell tumor88 / 263845333
glioma22 / 106883205
head and neck tumor32 / 136302234
kidney tumor10 / 68959145
leukemia12 / 95842125
liver tumor24 / 96359249
lung tumor4 / 10312738
lymphoma16 / 71755222
non-neoplasia10 / 97250102
normal554 / 3360307164
ovarian tumor9 / 76682117
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS45 / 125680358
prostate cancer20 / 102680194
retinoblastoma17 / 46356366
skin tumor17 / 124949136
soft tissue/muscle tissue tumor20 / 125191159
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites10 / 40015249
bladder3 / 29757100
blood23 / 123478186
bone14 / 71655195
bone marrow5 / 48801102
brain224 / 1100989203
cervix13 / 48171269
connective tissue15 / 149255100
ear5 / 16212308
embryonic tissue69 / 215722319
esophagus7 / 20209346
eye41 / 211054194
heart8 / 8962689
intestine21 / 23447289
kidney29 / 211777136
larynx2 / 2414582
liver41 / 207743197
lung23 / 33697468
lymph8 / 44270180
lymph node11 / 91610120
mammary gland29 / 153271189
mouth15 / 67052223
muscle21 / 107715194
nerve0 / 157680 
ovary18 / 102051176
pancreas23 / 214812107
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland3 / 16585180
placenta44 / 280825156
prostate31 / 189345163
salivary gland5 / 20155248
skin37 / 210574175
spleen10 / 53952185
stomach14 / 96619144
testis50 / 330442151
thymus26 / 81131320
thyroid13 / 47473273
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus37 / 232878158
vascular17 / 51780328
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208766_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1584
Adipocyte75.05
AdrenalCortex57.65
Adrenalgland101.25
Amygdala492.55
Appendix69.1
AtrioventricularNode9.25
BDCA4+_DentriticCells606.1
Bonemarrow121.4
BronchialEpithelialCells307.55
CD105+_Endothelial1210.25
CD14+_Monocytes427.15
CD19+_BCells(neg._sel.)688.45
CD33+_Myeloid584.15
CD34+1536.4
CD4+_Tcells568.75
CD56+_NKCells910.45
CD71+_EarlyErythroid322.15
CD8+_Tcells714.15
CardiacMyocytes195.15
Caudatenucleus145.55
Cerebellum94.15
CerebellumPeduncles114.05
CiliaryGanglion21.05
CingulateCortex97.75
Colorectaladenocarcinoma480.6
DorsalRootGanglion27.35
FetalThyroid124.9
Fetalbrain527.35
Fetalliver211.9
Fetallung257.75
GlobusPallidus64.75
Heart8.05
Hypothalamus267.85
Kidney28.65
Leukemia_chronicMyelogenousK-562252.8
Leukemia_promyelocytic-HL-60722.15
Leukemialymphoblastic(MOLT-4)629.8
Liver10.15
Lung51.85
Lymphnode264.6
Lymphoma_burkitts(Daudi)530.05
Lymphoma_burkitts(Raji)392.55
MedullaOblongata125.25
OccipitalLobe160.1
OlfactoryBulb102.85
Ovary67.7
Pancreas107.3
PancreaticIslet201.3
ParietalLobe94.45
Pituitary268.2
Placenta387.45
Pons76.9
PrefrontalCortex316.05
Prostate335.85
Salivarygland131.9
SkeletalMuscle12.1
Skin39.75
SmoothMuscle256.75
Spinalcord207.95
SubthalamicNucleus74
SuperiorCervicalGanglion19
TemporalLobe42.25
Testis78.35
TestisGermCell98.2
TestisIntersitial60.35
TestisLeydigCell49.55
TestisSeminiferousTubule77.5
Thalamus117
Thymus306.7
Thyroid580.6
Tongue87.45
Tonsil173.6
Trachea148.35
TrigeminalGanglion11.8
Uterus414.45
UterusCorpus13.25
WholeBlood285.05
Wholebrain156.05
colon702.7
pineal_day441.06
pineal_night514.04
retina267.9
small_intestine674.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P45726
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.9 ± 0.23
Basal Forebrain8.82 ± 0.25
Basal Part of Pons9 ± 0.2
Cerebellar Cortex9.06 ± 0.16
Cerebellar Nuclei8.83 ± 0.23
Claustrum8.87 ± 0.28
Epithalamus8.98 ± 0.28
Frontal Lobe8.88 ± 0.22
Globus Pallidus8.93 ± 0.17
Hypothalamus8.92 ± 0.18
Insula9.04 ± 0.32
Limbic Lobe8.87 ± 0.28
Mesencephalon8.82 ± 0.24
Myelencephalon8.83 ± 0.25
Occipital Lobe8.87 ± 0.22
Parietal Lobe8.82 ± 0.23
Pontine Tegmentum8.87 ± 0.21
Striatum8.78 ± 0.25
Subthalamus9.03 ± 0.13
Temporal Lobe8.91 ± 0.21
Thalamus8.72 ± 0.25
White Matter9.46 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HnrprRHPRetrohippocampal region0.09
0.13
HnrprsAMYStriatum-like amygdalar nuclei0.09
0.11
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HNRPR_HUMAN_0 0 0 0 HLGVCISVANNR PRIDE
HNRPR_HUMAN_187 8 187 194 AGPIWDLR PRIDE
HNRPR_HUMAN_235 12 235 246 HLGVCISVANNR PRIDE
HNRPR_HUMAN_346 13 346 358 NLATTVTEEILEK PRIDE
HNRPR_HUMAN_347 13 347 359 NLATTVTEEILEK PRIDE
HNRPR_HUMAN_428 14 428 441 STAYEDYYYHPPPR PRIDE
PAp00001877 19 217 235 EAAQEAVKLCDSYEIRPGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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