AutismKB 2.0

Annotation Detail for CDK9


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Basic Information Top
Gene Symbol:CDK9 ( C-2k,CDC2L4,CTK1,PITALRE,TAK )
Gene Full Name: cyclin-dependent kinase 9
Band: 9q34.11
Quick LinksEntrez ID:1025; OMIM: 603251; Uniprot ID:CDK9_HUMAN; ENSEMBL ID: ENSG00000136807; HGNC ID: 1780
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor5 / 34366145
chondrosarcoma1 / 8282312
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma4 / 10688337
head and neck tumor7 / 13630251
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal101 / 336030730
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone3 / 7165541
bone marrow1 / 4880120
brain15 / 110098913
cervix6 / 48171124
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye4 / 21105418
heart2 / 8962622
intestine16 / 23447268
kidney8 / 21177737
larynx0 / 241450 
liver4 / 20774319
lung13 / 33697438
lymph0 / 442700 
lymph node7 / 9161076
mammary gland7 / 15327145
mouth0 / 670520 
muscle1 / 1077159
nerve2 / 15768126
ovary7 / 10205168
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta12 / 28082542
prostate5 / 18934526
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach2 / 9661920
testis3 / 3304429
thymus5 / 8113161
thyroid7 / 47473147
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203198_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.5
Adipocyte6.2
AdrenalCortex7.25
Adrenalgland6
Amygdala10.15
Appendix7
AtrioventricularNode4.35
BDCA4+_DentriticCells48
Bonemarrow6.85
BronchialEpithelialCells7.1
CD105+_Endothelial10.7
CD14+_Monocytes12.2
CD19+_BCells(neg._sel.)27
CD33+_Myeloid19.4
CD34+26.05
CD4+_Tcells23.05
CD56+_NKCells60.65
CD71+_EarlyErythroid10.2
CD8+_Tcells33.4
CardiacMyocytes9
Caudatenucleus6.5
Cerebellum5.65
CerebellumPeduncles8.05
CiliaryGanglion4.05
CingulateCortex8.4
Colorectaladenocarcinoma7.2
DorsalRootGanglion4.7
FetalThyroid6.8
Fetalbrain7.7
Fetalliver6.1
Fetallung6.4
GlobusPallidus4.3
Heart9.3
Hypothalamus11.55
Kidney5.65
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-606.05
Leukemialymphoblastic(MOLT-4)5.85
Liver13.4
Lung11.15
Lymphnode6.8
Lymphoma_burkitts(Daudi)8.9
Lymphoma_burkitts(Raji)12.1
MedullaOblongata6.6
OccipitalLobe6.45
OlfactoryBulb5.65
Ovary5.25
Pancreas5.7
PancreaticIslet7.05
ParietalLobe7.4
Pituitary8.25
Placenta7.85
Pons6.7
PrefrontalCortex9.15
Prostate8.55
Salivarygland5.7
SkeletalMuscle7.85
Skin3.6
SmoothMuscle9.7
Spinalcord7.7
SubthalamicNucleus5
SuperiorCervicalGanglion7.85
TemporalLobe6.45
Testis7.65
TestisGermCell6.5
TestisIntersitial6
TestisLeydigCell7.05
TestisSeminiferousTubule6.15
Thalamus7.25
Thymus6.5
Thyroid14.5
Tongue6.8
Tonsil5.9
Trachea6
TrigeminalGanglion6.9
Uterus7.2
UterusCorpus6.35
WholeBlood8
Wholebrain10.65
colon7.25
pineal_day12.56
pineal_night14.56
retina8.75
small_intestine5.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P309929
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.33 ± 0.77
Basal Forebrain2.7 ± 0.42
Basal Part of Pons2.93 ± 0.24
Cerebellar Cortex3.8 ± 0.39
Cerebellar Nuclei3.36 ± 0.65
Claustrum2.97 ± 0.68
Epithalamus2.97 ± 0.75
Frontal Lobe3.25 ± 0.68
Globus Pallidus2.63 ± 0.39
Hypothalamus3.05 ± 0.48
Insula3.38 ± 0.35
Limbic Lobe3.17 ± 0.59
Mesencephalon3.22 ± 0.57
Myelencephalon3.17 ± 0.67
Occipital Lobe3.32 ± 0.56
Parietal Lobe3.21 ± 0.66
Pontine Tegmentum3.17 ± 0.84
Striatum2.35 ± 0.86
Subthalamus3.13 ± 0.7
Temporal Lobe3.21 ± 0.65
Thalamus2.97 ± 0.63
White Matter2.38 ± 1.06
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdk9CBCerebellum37.3
57.71
Cdk9CTXCerebral cortex100
100
Cdk9HIPHippocampal region100
100
Cdk9HPFHippocampal formation100
100
Cdk9HYHypothalamus94.99
92.49
Cdk9LSXLateral septal complex100
100
Cdk9MBMidbrain100
100
Cdk9MYMedulla78.76
100
Cdk9OLFOlfactory bulb100
100
Cdk9PPons75
95.52
Cdk9PALPallidum87.39
97.8
Cdk9RHPRetrohippocampal region100
100
Cdk9sAMYStriatum-like amygdalar nuclei100
100
Cdk9STRStriatum100
100
Cdk9STRdStriatum dorsal region100
100
Cdk9STRvStriatum ventral region100
100
Cdk9THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010349 12 75 86 HENVVNLIEICR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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