AutismKB 2.0

Annotation Detail for STUB1


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Basic Information Top
Gene Symbol:STUB1 ( CHIP,HSPABP2,NY-CO-7,SDCCAG7,UBOX1 )
Gene Full Name: STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
Band: 16p13.3
Quick LinksEntrez ID:10273; OMIM: 607207; Uniprot ID:CHIP_HUMAN; ENSEMBL ID: ENSG00000103266; HGNC ID: 11427
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult132 / 193912168
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor11 / 94178116
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor12 / 114246105
esophageal tumor1 / 1729057
gastrointestinal tumor17 / 119369142
germ cell tumor12 / 26384545
glioma11 / 106883102
head and neck tumor12 / 13630288
kidney tumor8 / 68959116
leukemia5 / 9584252
liver tumor3 / 9635931
lung tumor11 / 103127106
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal152 / 336030745
ovarian tumor7 / 7668291
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor30 / 124949240
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood6 / 12347848
bone8 / 71655111
bone marrow0 / 488010 
brain85 / 110098977
cervix3 / 4817162
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus1 / 2020949
eye12 / 21105456
heart2 / 8962622
intestine18 / 23447276
kidney14 / 21177766
larynx0 / 241450 
liver7 / 20774333
lung25 / 33697474
lymph0 / 442700 
lymph node8 / 9161087
mammary gland20 / 153271130
mouth1 / 6705214
muscle5 / 10771546
nerve3 / 15768190
ovary12 / 102051117
pancreas17 / 21481279
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta11 / 28082539
prostate13 / 18934568
salivary gland9 / 20155446
skin37 / 210574175
spleen0 / 539520 
stomach2 / 9661920
testis10 / 33044230
thymus0 / 811310 
thyroid1 / 4747321
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217934_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts177.75
Adipocyte206.35
AdrenalCortex154.15
Adrenalgland161
Amygdala229.7
Appendix73.15
AtrioventricularNode12.85
BDCA4+_DentriticCells178.9
Bonemarrow78.95
BronchialEpithelialCells305.6
CD105+_Endothelial164.2
CD14+_Monocytes165.75
CD19+_BCells(neg._sel.)182.75
CD33+_Myeloid178.05
CD34+184.8
CD4+_Tcells158.25
CD56+_NKCells249.55
CD71+_EarlyErythroid63.8
CD8+_Tcells143.1
CardiacMyocytes259.05
Caudatenucleus200.95
Cerebellum247.95
CerebellumPeduncles358.9
CiliaryGanglion39.05
CingulateCortex207.9
Colorectaladenocarcinoma141
DorsalRootGanglion43.8
FetalThyroid433.75
Fetalbrain145.8
Fetalliver67.4
Fetallung131.05
GlobusPallidus104
Heart306.45
Hypothalamus274.4
Kidney186.15
Leukemia_chronicMyelogenousK-562137.5
Leukemia_promyelocytic-HL-60112.05
Leukemialymphoblastic(MOLT-4)150.25
Liver187.2
Lung248.1
Lymphnode124.8
Lymphoma_burkitts(Daudi)106.25
Lymphoma_burkitts(Raji)192.15
MedullaOblongata144.9
OccipitalLobe185.4
OlfactoryBulb144.75
Ovary69.95
Pancreas112.95
PancreaticIslet130.45
ParietalLobe162.2
Pituitary173.45
Placenta109.55
Pons132.85
PrefrontalCortex306.95
Prostate191.1
Salivarygland48.5
SkeletalMuscle93.55
Skin65.5
SmoothMuscle302.6
Spinalcord185.05
SubthalamicNucleus159.35
SuperiorCervicalGanglion42.85
TemporalLobe169
Testis160.5
TestisGermCell91.65
TestisIntersitial67.6
TestisLeydigCell133.45
TestisSeminiferousTubule122.45
Thalamus216.35
Thymus124.8
Thyroid199.15
Tongue125.7
Tonsil128.85
Trachea87.95
TrigeminalGanglion85.7
Uterus103
UterusCorpus108.35
WholeBlood102.85
Wholebrain449.5
colon104.55
pineal_day221.12
pineal_night216.36
retina163.6
small_intestine103.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P37870
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.71 ± 0.59
Basal Forebrain10.04 ± 0.13
Basal Part of Pons10.46 ± 0.36
Cerebellar Cortex10.19 ± 0.34
Cerebellar Nuclei10.1 ± 0.35
Claustrum9.71 ± 0.66
Epithalamus10.03 ± 0.14
Frontal Lobe10.28 ± 0.33
Globus Pallidus9.81 ± 0.35
Hypothalamus10.21 ± 0.19
Insula10.31 ± 0.18
Limbic Lobe9.9 ± 0.53
Mesencephalon9.86 ± 0.4
Myelencephalon10 ± 0.47
Occipital Lobe9.51 ± 0.55
Parietal Lobe10.1 ± 0.38
Pontine Tegmentum10.03 ± 0.44
Striatum9.47 ± 0.41
Subthalamus10.31 ± 0.43
Temporal Lobe10.23 ± 0.34
Thalamus10.05 ± 0.39
White Matter9.31 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Stub1CBCerebellum43.84
82.61
Stub1CTXCerebral cortex100
100
Stub1HIPHippocampal region74.69
100
Stub1HPFHippocampal formation92.78
100
Stub1HYHypothalamus96.18
93.23
Stub1LSXLateral septal complex85.5
68.9
Stub1MBMidbrain78.42
80.76
Stub1MYMedulla87.58
100
Stub1OLFOlfactory bulb100
100
Stub1PPons78.7
99.06
Stub1PALPallidum80.1
88.85
Stub1RHPRetrohippocampal region100
100
Stub1sAMYStriatum-like amygdalar nuclei100
100
Stub1STRStriatum94.68
82.33
Stub1STRdStriatum dorsal region93.16
82.44
Stub1STRvStriatum ventral region97.23
77.2
Stub1THThalamus87.42
87.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004654 11 41 51 KYPEAAACYGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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