Annotation Detail for NET1
Basic Information Top
| Gene Symbol: | NET1 ( ARHGEF8,NET1A ) |
|---|---|
| Gene Full Name: | neuroepithelial cell transforming 1 |
| Band: | 10p15.1 |
| Quick Links | Entrez ID:10276; OMIM: 606450; Uniprot ID:ARHG8_HUMAN; ENSEMBL ID: ENSG00000173848; HGNC ID: 14592 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.25155
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 21 / 70761 | 296 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 52 / 564012 | 92 | |
| neonate | 2 / 31097 | 64 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 1 / 55556 | 17 | |
| adult | 259 / 1939121 | 133 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 13 / 17290 | 751 | |
| gastrointestinal tumor | 52 / 119369 | 435 | |
| germ cell tumor | 53 / 263845 | 200 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 50 / 136302 | 366 | |
| kidney tumor | 11 / 68959 | 159 | |
| leukemia | 20 / 95842 | 208 | |
| liver tumor | 11 / 96359 | 114 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 10 / 97250 | 102 | |
| normal | 353 / 3360307 | 105 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 7 / 125680 | 55 | |
| prostate cancer | 23 / 102680 | 223 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 42 / 40015 | 1049 |  |
| bladder | 7 / 29757 | 235 | |
| blood | 6 / 123478 | 48 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 18 / 48801 | 368 | |
| brain | 120 / 1100989 | 108 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 14 / 149255 | 93 | |
| ear | 4 / 16212 | 246 | |
| embryonic tissue | 32 / 215722 | 148 | |
| esophagus | 14 / 20209 | 692 | |
| eye | 11 / 211054 | 52 | |
| heart | 12 / 89626 | 133 | |
| intestine | 18 / 234472 | 76 | |
| kidney | 26 / 211777 | 122 | |
| larynx | 3 / 24145 | 124 | |
| liver | 13 / 207743 | 62 | |
| lung | 21 / 336974 | 62 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 6 / 153271 | 39 | |
| mouth | 49 / 67052 | 730 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 2 / 214812 | 9 |  |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 63 / 280825 | 224 | |
| prostate | 33 / 189345 | 174 | |
| salivary gland | 8 / 20155 | 396 | |
| skin | 12 / 210574 | 56 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 10 / 96619 | 103 | |
| testis | 56 / 330442 | 169 | |
| thymus | 28 / 81131 | 345 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 74 / 52413 | 1411 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 31 / 232878 | 133 | |
| vascular | 5 / 51780 | 96 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 201829_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 59.5 | |
| Adipocyte | 41.6 | |
| AdrenalCortex | 43.5 | |
| Adrenalgland | 27.65 | |
| Amygdala | 41.7 | |
| Appendix | 55.35 | |
| AtrioventricularNode | 58.5 | |
| BDCA4+_DentriticCells | 40.55 | |
| Bonemarrow | 34.45 | |
| BronchialEpithelialCells | 595.9 | |
| CD105+_Endothelial | 172.2 | |
| CD14+_Monocytes | 29.3 | |
| CD19+_BCells(neg._sel.) | 38.25 | |
| CD33+_Myeloid | 36.55 | |
| CD34+ | 226.7 | |
| CD4+_Tcells | 40.85 | |
| CD56+_NKCells | 43.2 | |
| CD71+_EarlyErythroid | 103.05 | |
| CD8+_Tcells | 19.1 | |
| CardiacMyocytes | 49.45 | |
| Caudatenucleus | 38.3 | |
| Cerebellum | 21.5 | |
| CerebellumPeduncles | 51.45 | |
| CiliaryGanglion | 50.35 | |
| CingulateCortex | 48.5 | |
| Colorectaladenocarcinoma | 871.25 | |
| DorsalRootGanglion | 48.6 | |
| FetalThyroid | 41.2 | |
| Fetalbrain | 33.7 | |
| Fetalliver | 39.7 | |
| Fetallung | 70.05 | |
| GlobusPallidus | 27.1 | |
| Heart | 40.45 | |
| Hypothalamus | 104.45 | |
| Kidney | 38.1 | |
| Leukemia_chronicMyelogenousK-562 | 298.2 | |
| Leukemia_promyelocytic-HL-60 | 36.3 | |
| Leukemialymphoblastic(MOLT-4) | 52.1 | |
| Liver | 40.3 | |
| Lung | 21.3 | |
| Lymphnode | 29.2 | |
| Lymphoma_burkitts(Daudi) | 56.95 | |
| Lymphoma_burkitts(Raji) | 41.35 | |
| MedullaOblongata | 37.1 | |
| OccipitalLobe | 40.7 | |
| OlfactoryBulb | 53.05 | |
| Ovary | 31.1 | |
| Pancreas | 96.55 | |
| PancreaticIslet | 68 | |
| ParietalLobe | 47.6 | |
| Pituitary | 50.6 | |
| Placenta | 315.35 | |
| Pons | 39.65 | |
| PrefrontalCortex | 94.65 | |
| Prostate | 127 | |
| Salivarygland | 48.75 | |
| SkeletalMuscle | 47.85 | |
| Skin | 48.45 | |
| SmoothMuscle | 39 | |
| Spinalcord | 62.35 | |
| SubthalamicNucleus | 56.25 | |
| SuperiorCervicalGanglion | 78.5 | |
| TemporalLobe | 38.2 | |
| Testis | 23.25 | |
| TestisGermCell | 35.65 | |
| TestisIntersitial | 36.5 | |
| TestisLeydigCell | 43.8 | |
| TestisSeminiferousTubule | 38.25 | |
| Thalamus | 49.95 | |
| Thymus | 25.8 | |
| Thyroid | 79.45 | |
| Tongue | 78.75 | |
| Tonsil | 60.95 | |
| Trachea | 89.75 | |
| TrigeminalGanglion | 64.3 | |
| Uterus | 246 | |
| UterusCorpus | 37.45 | |
| WholeBlood | 20.6 | |
| Wholebrain | 34.2 | |
| colon | 844.05 | |
| pineal_day | 45.3 | |
| pineal_night | 56.26 | |
| retina | 102.025 | |
| small_intestine | 383.15 | |
- Probe name: CUST_13026_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.67 ± 0.53 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.95 ± 0.52 | |
| Basal Part of Pons | 3.7 ± 0.4 | |
| Cerebellar Cortex | 4.09 ± 0.43 | |
| Cerebellar Nuclei | 4.65 ± 0.68 | |
| Claustrum | 3.84 ± 0.43 | |
| Epithalamus | 4.65 ± 0.45 | |
| Frontal Lobe | 4.1 ± 0.57 | |
| Globus Pallidus | 5.37 ± 0.28 | |
| Hypothalamus | 3.72 ± 0.65 | |
| Insula | 4.05 ± 0.52 | |
| Limbic Lobe | 4.11 ± 0.59 | |
| Mesencephalon | 4.33 ± 0.63 | |
| Myelencephalon | 4.28 ± 0.6 | |
| Occipital Lobe | 4.26 ± 0.68 | |
| Parietal Lobe | 4.1 ± 0.5 | |
| Pontine Tegmentum | 4.31 ± 0.57 | |
| Striatum | 4.65 ± 0.55 | |
| Subthalamus | 4.42 ± 0.54 | |
| Temporal Lobe | 4.03 ± 0.53 | |
| Thalamus | 4.53 ± 0.49 | |
| White Matter | 5.36 ± 0.49 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Net1 | CB | Cerebellum | 29.08 | |
| 34.87 | | |||
| Net1 | CTX | Cerebral cortex | 73.22 | |
| 64.25 | | |||
| Net1 | HIP | Hippocampal region | 55.91 | |
| 79.78 | | |||
| Net1 | HPF | Hippocampal formation | 47.52 | |
| 64.18 | | |||
| Net1 | HY | Hypothalamus | 10.85 | |
| 9.3 | | |||
| Net1 | LSX | Lateral septal complex | 24.43 | |
| 19.28 | | |||
| Net1 | MB | Midbrain | 16.17 | |
| 15.4 | | |||
| Net1 | MY | Medulla | 21.98 | |
| 24.57 | | |||
| Net1 | OLF | Olfactory bulb | 60.84 | |
| 58.61 | | |||
| Net1 | P | Pons | 13.33 | |
| 14.51 | | |||
| Net1 | PAL | Pallidum | 11.24 | |
| 10.04 | | |||
| Net1 | RHP | Retrohippocampal region | 37.25 | |
| 33.75 | | |||
| Net1 | sAMY | Striatum-like amygdalar nuclei | 13.83 | |
| 10.77 | | |||
| Net1 | STR | Striatum | 20.68 | |
| 15.37 | | |||
| Net1 | STRd | Striatum dorsal region | 17.82 | |
| 12.89 | | |||
| Net1 | STRv | Striatum ventral region | 31.47 | |
| 22.64 | | |||
| Net1 | TH | Thalamus | 32.16 | |
| 30.94 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| ARHG8_HUMAN_131 | 11 | 131 | 141 | SPASAQKFSSR | PRIDE |
| ARHG8_HUMAN_429 | 19 | 429 | 447 | QPIPVQELVLEDLQDGDVR | PRIDE |