AutismKB 2.0

Annotation Detail for ADAR


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Basic Information Top
Gene Symbol:ADAR ( ADAR1,DRADA,DSH,DSRAD,G1P1,IFI-4,IFI4,K88DSRBP,P136 )
Gene Full Name: adenosine deaminase, RNA-specific
Band: 1q21.3
Quick LinksEntrez ID:103; OMIM: 146920; Uniprot ID:DSRAD_HUMAN; ENSEMBL ID: ENSG00000160710; HGNC ID: 225
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body20 / 70761282
blastocyst16 / 62319256
fetus67 / 564012118
neonate3 / 3109796
infant1 / 2362042
juvenile4 / 5555671
adult372 / 1939121191
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma1 / 1747557
breast (mammary gland) tumor27 / 94178286
cervical tumor2 / 3436658
chondrosarcoma25 / 82823301
colorectal tumor39 / 114246341
esophageal tumor1 / 1729057
gastrointestinal tumor23 / 119369192
germ cell tumor45 / 263845170
glioma19 / 106883177
head and neck tumor40 / 136302293
kidney tumor10 / 68959145
leukemia17 / 95842177
liver tumor33 / 96359342
lung tumor36 / 103127349
lymphoma16 / 71755222
non-neoplasia13 / 97250133
normal469 / 3360307139
ovarian tumor9 / 76682117
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer23 / 102680223
retinoblastoma5 / 46356107
skin tumor24 / 124949192
soft tissue/muscle tissue tumor23 / 125191183
uterine tumor34 / 90257376
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland4 / 33197120
ascites7 / 40015174
bladder3 / 29757100
blood14 / 123478113
bone21 / 71655293
bone marrow6 / 48801122
brain134 / 1100989121
cervix3 / 4817162
connective tissue17 / 149255113
ear3 / 16212185
embryonic tissue48 / 215722222
esophagus1 / 2020949
eye38 / 211054180
heart7 / 8962678
intestine61 / 234472260
kidney19 / 21177789
larynx1 / 2414541
liver43 / 207743206
lung63 / 336974186
lymph13 / 44270293
lymph node36 / 91610392
mammary gland35 / 153271228
mouth15 / 67052223
muscle8 / 10771574
nerve5 / 15768317
ovary9 / 10205188
pancreas18 / 21481283
parathyroid4 / 20539194
pharynx5 / 41328120
pituitary gland3 / 16585180
placenta30 / 280825106
prostate31 / 189345163
salivary gland7 / 20155347
skin37 / 210574175
spleen9 / 53952166
stomach15 / 96619155
testis30 / 33044290
thymus7 / 8113186
thyroid21 / 47473442
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord5 / 13680365
uterus66 / 232878283
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201786_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1552.25
Adipocyte131.15
AdrenalCortex77.5
Adrenalgland202.7
Amygdala436.45
Appendix55.3
AtrioventricularNode30.1
BDCA4+_DentriticCells1050.1
Bonemarrow296.55
BronchialEpithelialCells294.7
CD105+_Endothelial443.9
CD14+_Monocytes882.85
CD19+_BCells(neg._sel.)741.9
CD33+_Myeloid1194.35
CD34+771.85
CD4+_Tcells1352.45
CD56+_NKCells950
CD71+_EarlyErythroid125.1
CD8+_Tcells1271.45
CardiacMyocytes179.6
Caudatenucleus376.6
Cerebellum204.6
CerebellumPeduncles332.45
CiliaryGanglion22.95
CingulateCortex360.85
Colorectaladenocarcinoma286.85
DorsalRootGanglion27.7
FetalThyroid258.55
Fetalbrain285.85
Fetalliver104.1
Fetallung212.45
GlobusPallidus123.85
Heart119.9
Hypothalamus614
Kidney150.9
Leukemia_chronicMyelogenousK-562198.4
Leukemia_promyelocytic-HL-60356.15
Leukemialymphoblastic(MOLT-4)389.1
Liver251.2
Lung407
Lymphnode471.55
Lymphoma_burkitts(Daudi)960.3
Lymphoma_burkitts(Raji)451.3
MedullaOblongata291.6
OccipitalLobe360.45
OlfactoryBulb266.5
Ovary28.4
Pancreas122.75
PancreaticIslet294.45
ParietalLobe287.75
Pituitary483.8
Placenta474.75
Pons223.6
PrefrontalCortex801.65
Prostate393.25
Salivarygland133.35
SkeletalMuscle13.65
Skin26.15
SmoothMuscle423.7
Spinalcord302.4
SubthalamicNucleus238.4
SuperiorCervicalGanglion45.15
TemporalLobe162.45
Testis175.9
TestisGermCell376.75
TestisIntersitial120.45
TestisLeydigCell66.15
TestisSeminiferousTubule163.85
Thalamus407.35
Thymus688.25
Thyroid258.1
Tongue72
Tonsil378.2
Trachea156.5
TrigeminalGanglion39.6
Uterus277.75
UterusCorpus70.2
WholeBlood1489
Wholebrain394.85
colon245.05
pineal_day1344.82
pineal_night1440.82
retina526.175
small_intestine437
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P200439
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.31 ± 0.36
Basal Forebrain6.6 ± 0.19
Basal Part of Pons6.65 ± 0.27
Cerebellar Cortex6.42 ± 0.29
Cerebellar Nuclei6.43 ± 0.27
Claustrum6.65 ± 0.27
Epithalamus6.43 ± 0.24
Frontal Lobe6.5 ± 0.31
Globus Pallidus6.29 ± 0.28
Hypothalamus6.78 ± 0.19
Insula6.49 ± 0.26
Limbic Lobe6.51 ± 0.31
Mesencephalon6.59 ± 0.35
Myelencephalon6.53 ± 0.31
Occipital Lobe6.52 ± 0.3
Parietal Lobe6.53 ± 0.35
Pontine Tegmentum6.47 ± 0.35
Striatum6.63 ± 0.29
Subthalamus6.49 ± 0.55
Temporal Lobe6.55 ± 0.28
Thalamus6.48 ± 0.28
White Matter6.36 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AdarCBCerebellum100
100
AdarCTXCerebral cortex100
100
AdarHIPHippocampal region100
100
AdarHPFHippocampal formation100
100
AdarHYHypothalamus100
100
AdarLSXLateral septal complex100
100
AdarMBMidbrain100
100
AdarMYMedulla100
100
AdarOLFOlfactory bulb100
100
AdarPPons100
100
AdarPALPallidum100
100
AdarRHPRetrohippocampal region100
100
AdarsAMYStriatum-like amygdalar nuclei100
100
AdarSTRStriatum100
100
AdarSTRdStriatum dorsal region100
100
AdarSTRvStriatum ventral region100
100
AdarTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DSRAD_HUMAN_329 11 329 339 DINAVLIDMER PRIDE
DSRAD_HUMAN_423 9 423 431 QEARPEPAR PRIDE
PAp00000971 16 894 909 CFNTLTNSFQPSLLGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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