AutismKB 2.0

Annotation Detail for LANCL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LANCL1 ( GPR69A,p40 )
Gene Full Name: LanC lantibiotic synthetase component C-like 1 (bacterial)
Band: 2q34
Quick LinksEntrez ID:10314; OMIM: 604155; Uniprot ID:LANC1_HUMAN; ENSEMBL ID: ENSG00000115365; HGNC ID: 6508
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst8 / 62319128
fetus57 / 564012101
neonate1 / 3109732
infant3 / 23620127
juvenile7 / 55556125
adult131 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor17 / 94178180
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor21 / 26384579
glioma11 / 106883102
head and neck tumor12 / 13630288
kidney tumor12 / 68959174
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma4 / 7175555
non-neoplasia8 / 9725082
normal591 / 3360307175
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma5 / 46356107
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland6 / 33197180
ascites1 / 4001524
bladder2 / 2975767
blood2 / 12347816
bone3 / 7165541
bone marrow2 / 4880140
brain460 / 1100989417
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus1 / 2020949
eye13 / 21105461
heart4 / 8962644
intestine19 / 23447281
kidney20 / 21177794
larynx0 / 241450 
liver7 / 20774333
lung17 / 33697450
lymph1 / 4427022
lymph node8 / 9161087
mammary gland18 / 153271117
mouth14 / 67052208
muscle9 / 10771583
nerve1 / 1576863
ovary1 / 1020519
pancreas6 / 21481227
parathyroid5 / 20539243
pharynx1 / 4132824
pituitary gland3 / 16585180
placenta11 / 28082539
prostate5 / 18934526
salivary gland0 / 201550 
skin10 / 21057447
spleen2 / 5395237
stomach1 / 9661910
testis63 / 330442190
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus16 / 23287868
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202019_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.9
Adipocyte6.5
AdrenalCortex6.65
Adrenalgland5.4
Amygdala7.15
Appendix6.55
AtrioventricularNode7.4
BDCA4+_DentriticCells7.05
Bonemarrow6.4
BronchialEpithelialCells6.3
CD105+_Endothelial6.3
CD14+_Monocytes6.55
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid7.45
CD34+7.9
CD4+_Tcells6.95
CD56+_NKCells7.5
CD71+_EarlyErythroid6
CD8+_Tcells6.35
CardiacMyocytes8.3
Caudatenucleus5.8
Cerebellum8.95
CerebellumPeduncles8.65
CiliaryGanglion4.95
CingulateCortex8.4
Colorectaladenocarcinoma6.5
DorsalRootGanglion5.9
FetalThyroid6.25
Fetalbrain6.5
Fetalliver5.7
Fetallung5.35
GlobusPallidus9.9
Heart8.15
Hypothalamus7.4
Kidney5.3
Leukemia_chronicMyelogenousK-5625.9
Leukemia_promyelocytic-HL-605.7
Leukemialymphoblastic(MOLT-4)5.25
Liver9
Lung7.25
Lymphnode5.5
Lymphoma_burkitts(Daudi)8.65
Lymphoma_burkitts(Raji)9.7
MedullaOblongata9.2
OccipitalLobe42.5
OlfactoryBulb5.15
Ovary5.15
Pancreas5.25
PancreaticIslet6.95
ParietalLobe8.3
Pituitary7.85
Placenta6.2
Pons8.5
PrefrontalCortex8.15
Prostate7.55
Salivarygland5.1
SkeletalMuscle7.85
Skin5.1
SmoothMuscle7.35
Spinalcord6.95
SubthalamicNucleus6.5
SuperiorCervicalGanglion9.2
TemporalLobe5.65
Testis33.55
TestisGermCell21.6
TestisIntersitial35.8
TestisLeydigCell11.15
TestisSeminiferousTubule20.1
Thalamus6.8
Thymus4.95
Thyroid8
Tongue6.9
Tonsil6.3
Trachea5.4
TrigeminalGanglion8.15
Uterus5.2
UterusCorpus5.7
WholeBlood7
Wholebrain5.85
colon6.4
pineal_day7.5
pineal_night7.5
retina8.825
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P50887
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.84 ± 0.37
Basal Forebrain9.01 ± 0.19
Basal Part of Pons9.17 ± 0.29
Cerebellar Cortex8.89 ± 0.24
Cerebellar Nuclei9.51 ± 0.21
Claustrum8.96 ± 0.27
Epithalamus8.58 ± 0.39
Frontal Lobe9.17 ± 0.34
Globus Pallidus9.4 ± 0.34
Hypothalamus8.57 ± 0.28
Insula8.81 ± 0.25
Limbic Lobe9.15 ± 0.3
Mesencephalon9.07 ± 0.46
Myelencephalon9.12 ± 0.37
Occipital Lobe9.26 ± 0.27
Parietal Lobe9.18 ± 0.31
Pontine Tegmentum9.18 ± 0.25
Striatum9.37 ± 0.32
Subthalamus9.25 ± 0.27
Temporal Lobe8.99 ± 0.28
Thalamus9.25 ± 0.3
White Matter10.7 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lancl1CBCerebellum65.02
100
Lancl1CTXCerebral cortex100
100
Lancl1HIPHippocampal region100
100
Lancl1HPFHippocampal formation100
100
Lancl1HYHypothalamus84.9
85.6
Lancl1LSXLateral septal complex95.68
91.43
Lancl1MBMidbrain84.48
92.36
Lancl1MYMedulla80.33
100
Lancl1OLFOlfactory bulb100
100
Lancl1PPons78.63
92.14
Lancl1PALPallidum83.39
89.49
Lancl1RHPRetrohippocampal region100
100
Lancl1sAMYStriatum-like amygdalar nuclei100
100
Lancl1STRStriatum100
100
Lancl1STRdStriatum dorsal region100
100
Lancl1STRvStriatum ventral region100
100
Lancl1THThalamus90.46
94.9
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LANC1_HUMAN_14 14 14 27 NKSLAEGYFDAAGR PRIDE
PAp00003987 22 174 195 IPQSHIQQICETILTSGENLAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved