AutismKB 2.0

Annotation Detail for LAMC3


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Basic Information Top
Gene Symbol:LAMC3 ( DKFZp434E202 )
Gene Full Name: laminin, gamma 3
Band: 9q34.12
Quick LinksEntrez ID:10319; OMIM: 604349; Uniprot ID:LAMC3_HUMAN; ENSEMBL ID: ENSG00000050555; HGNC ID: 6494
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal59 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth3 / 6705244
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219407_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.1
Adipocyte5.35
AdrenalCortex9.4
Adrenalgland8.65
Amygdala5.7
Appendix5.35
AtrioventricularNode4.15
BDCA4+_DentriticCells5.55
Bonemarrow5.4
BronchialEpithelialCells5.3
CD105+_Endothelial5.4
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)5.7
CD33+_Myeloid6.85
CD34+6.6
CD4+_Tcells5.5
CD56+_NKCells5.7
CD71+_EarlyErythroid6.65
CD8+_Tcells4.9
CardiacMyocytes7
Caudatenucleus5.05
Cerebellum4.55
CerebellumPeduncles7.05
CiliaryGanglion3.9
CingulateCortex6.45
Colorectaladenocarcinoma5.35
DorsalRootGanglion4.15
FetalThyroid5.3
Fetalbrain5.75
Fetalliver4.65
Fetallung4.85
GlobusPallidus3.9
Heart9
Hypothalamus6.2
Kidney5.2
Leukemia_chronicMyelogenousK-5624.85
Leukemia_promyelocytic-HL-604.8
Leukemialymphoblastic(MOLT-4)4.35
Liver7.1
Lung38.4
Lymphnode4.6
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)12.25
MedullaOblongata4.85
OccipitalLobe4.95
OlfactoryBulb4.2
Ovary4.05
Pancreas5.05
PancreaticIslet6.35
ParietalLobe5.7
Pituitary6.85
Placenta190.1
Pons5.15
PrefrontalCortex6.55
Prostate6.3
Salivarygland4.3
SkeletalMuscle9.25
Skin4.15
SmoothMuscle6.9
Spinalcord5.8
SubthalamicNucleus4.9
SuperiorCervicalGanglion6.3
TemporalLobe4.9
Testis79.7
TestisGermCell13.95
TestisIntersitial6.5
TestisLeydigCell6.55
TestisSeminiferousTubule10.05
Thalamus5.55
Thymus4.1
Thyroid6.9
Tongue5.25
Tonsil5.2
Trachea4.45
TrigeminalGanglion5.5
Uterus4.4
UterusCorpus6.25
WholeBlood5.65
Wholebrain4.5
colon5.45
pineal_day6.76
pineal_night6.88
retina7.625
small_intestine5.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_187_PI417507815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.14 ± 0.79
Basal Forebrain3.3 ± 0.43
Basal Part of Pons3.04 ± 0.27
Cerebellar Cortex2.84 ± 0.59
Cerebellar Nuclei3.84 ± 0.52
Claustrum2.97 ± 0.68
Epithalamus3.31 ± 0.66
Frontal Lobe3.44 ± 0.56
Globus Pallidus4.05 ± 0.58
Hypothalamus2.99 ± 0.71
Insula3.36 ± 0.63
Limbic Lobe3.28 ± 0.6
Mesencephalon3.3 ± 0.64
Myelencephalon3.45 ± 0.61
Occipital Lobe3.07 ± 0.62
Parietal Lobe3.09 ± 0.59
Pontine Tegmentum3.51 ± 0.69
Striatum4.06 ± 0.53
Subthalamus3.77 ± 0.4
Temporal Lobe3.32 ± 0.6
Thalamus3.48 ± 0.51
White Matter3.23 ± 0.83
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lamc3CBCerebellum2.22
3.61
Lamc3CTXCerebral cortex1.96
2.6
Lamc3HIPHippocampal region1.98
4.33
Lamc3HPFHippocampal formation1.98
3.36
Lamc3HYHypothalamus0.74
1.21
Lamc3LSXLateral septal complex0.75
1.03
Lamc3MBMidbrain1
1.37
Lamc3MYMedulla3.24
4.14
Lamc3OLFOlfactory bulb2.81
3.89
Lamc3PPons1.3
1.57
Lamc3PALPallidum0.5
0.5
Lamc3RHPRetrohippocampal region1.86
1.89
Lamc3sAMYStriatum-like amygdalar nuclei0.98
0.96
Lamc3STRStriatum0.64
0.61
Lamc3STRdStriatum dorsal region0.44
0.35
Lamc3STRvStriatum ventral region0.89
0.84
Lamc3THThalamus6.19
9.37
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01040832 14 588 601 HSSLSGPQDAGHPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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