AutismKB 2.0

Annotation Detail for CRISP3


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Basic Information Top
Gene Symbol:CRISP3 ( Aeg2,CRISP-3,CRS3,MGC126588,SGP28,dJ442L6.3 )
Gene Full Name: cysteine-rich secretory protein 3
Band: 6p12.3
Quick LinksEntrez ID:10321; OMIM: NA; Uniprot ID:CRIS3_HUMAN; ENSEMBL ID: ENSG00000096006; HGNC ID: 16904
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor5 / 17290289
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia14 / 95842146
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal61 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer31 / 102680301
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood14 / 123478113
bone31 / 71655432
bone marrow1 / 4880120
brain0 / 11009890 
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus6 / 20209296
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth3 / 6705244
muscle4 / 10771537
nerve0 / 157680 
ovary12 / 102051117
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate20 / 189345105
salivary gland16 / 20155793
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea119 / 524132270
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207802_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.9
Adipocyte8.9
AdrenalCortex14.05
Adrenalgland8.75
Amygdala8.5
Appendix13.3
AtrioventricularNode18.2
BDCA4+_DentriticCells8.15
Bonemarrow45
BronchialEpithelialCells8.6
CD105+_Endothelial8.95
CD14+_Monocytes10.25
CD19+_BCells(neg._sel.)9.4
CD33+_Myeloid10.75
CD34+14.3
CD4+_Tcells8.8
CD56+_NKCells10.25
CD71+_EarlyErythroid9.15
CD8+_Tcells7.7
CardiacMyocytes23.15
Caudatenucleus8.35
Cerebellum7.65
CerebellumPeduncles12.45
CiliaryGanglion10.4
CingulateCortex10.2
Colorectaladenocarcinoma9.05
DorsalRootGanglion10.45
FetalThyroid9.55
Fetalbrain8.7
Fetalliver8.25
Fetallung6.55
GlobusPallidus8.15
Heart17.25
Hypothalamus9.25
Kidney9.3
Leukemia_chronicMyelogenousK-5628.3
Leukemia_promyelocytic-HL-608.05
Leukemialymphoblastic(MOLT-4)6.9
Liver15.75
Lung9.9
Lymphnode7.25
Lymphoma_burkitts(Daudi)12.7
Lymphoma_burkitts(Raji)15.4
MedullaOblongata7.85
OccipitalLobe8.2
OlfactoryBulb7.1
Ovary7.9
Pancreas12.5
PancreaticIslet129.1
ParietalLobe11.35
Pituitary10.8
Placenta8.85
Pons9.95
PrefrontalCortex10.5
Prostate10.2
Salivarygland1429.35
SkeletalMuscle16.45
Skin11.65
SmoothMuscle10.45
Spinalcord9.85
SubthalamicNucleus10.2
SuperiorCervicalGanglion18.25
TemporalLobe9.1
Testis7.75
TestisGermCell7.05
TestisIntersitial8.45
TestisLeydigCell10.3
TestisSeminiferousTubule7.95
Thalamus10.1
Thymus6.6
Thyroid10.8
Tongue19.3
Tonsil9.65
Trachea1062.05
TrigeminalGanglion13.55
Uterus7
UterusCorpus10.8
WholeBlood9.7
Wholebrain6.7
colon8.85
pineal_day11.04
pineal_night10.7
retina10.925
small_intestine8.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14767_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.05 ± 1.03
Basal Forebrain1.64 ± 0.19
Basal Part of Pons1.5 ± 0.44
Cerebellar Cortex1.43 ± 0.63
Cerebellar Nuclei1.91 ± 0.74
Claustrum2.52 ± 0.89
Epithalamus1.28 ± 0.72
Frontal Lobe1.45 ± 0.56
Globus Pallidus2.17 ± 0.31
Hypothalamus1.72 ± 0.72
Insula1.48 ± 0.49
Limbic Lobe1.62 ± 0.7
Mesencephalon1.78 ± 0.71
Myelencephalon1.61 ± 0.67
Occipital Lobe1.62 ± 0.51
Parietal Lobe1.66 ± 0.82
Pontine Tegmentum1.65 ± 0.67
Striatum1.8 ± 0.69
Subthalamus1.77 ± 0.61
Temporal Lobe1.49 ± 0.61
Thalamus1.58 ± 0.59
White Matter2.13 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Crisp1CBCerebellum0.7
1.89
Crisp1CTXCerebral cortex0.57
0.82
Crisp1HIPHippocampal region0.63
0.68
Crisp1HPFHippocampal formation0.47
0.51
Crisp1HYHypothalamus2.86
4.15
Crisp1LSXLateral septal complex0.03
0
Crisp1MBMidbrain0.64
1.8
Crisp1MYMedulla0.97
1.58
Crisp1OLFOlfactory bulb2.88
4.81
Crisp1PPons2.68
5.77
Crisp1PALPallidum0.86
0.99
Crisp1RHPRetrohippocampal region0.07
0.09
Crisp1sAMYStriatum-like amygdalar nuclei0.27
1.87
Crisp1STRStriatum0.76
1.03
Crisp1STRdStriatum dorsal region0.1
0.12
Crisp1STRvStriatum ventral region3.56
3.77
Crisp1THThalamus0.44
0.57
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00060403 20 34 53 NEDKDPAFTALLTTQTQVQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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