Annotation Detail for COX4NB
Basic Information Top
| Gene Symbol: | COX4NB ( C16orf2,C16orf4,FAM158B,NOC4 ) |
|---|---|
| Gene Full Name: | COX4 neighbor |
| Band: | 16q24 |
| Quick Links | Entrez ID:10328; OMIM: 604886; Uniprot ID:CX4NB_HUMAN; ENSEMBL ID: ENSG00000131148; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.173162
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 6 / 70761 | 84 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 39 / 564012 | 69 | |
| neonate | 3 / 31097 | 96 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 121 / 1939121 | 62 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 8 / 82823 | 96 | |
| colorectal tumor | 7 / 114246 | 61 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 33 / 263845 | 125 | |
| glioma | 26 / 106883 | 243 |  |
| head and neck tumor | 7 / 136302 | 51 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 8 / 71755 | 111 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 150 / 3360307 | 44 | |
| ovarian tumor | 10 / 76682 | 130 | |
| pancreatic tumor | 13 / 104616 | 124 | |
| primitive neuroectodermal tumor of the CNS | 17 / 125680 | 135 | |
| prostate cancer | 19 / 102680 | 185 | |
| retinoblastoma | 9 / 46356 | 194 | |
| skin tumor | 22 / 124949 | 176 | |
| soft tissue/muscle tissue tumor | 15 / 125191 | 119 | |
| uterine tumor | 10 / 90257 | 110 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 4 / 123478 | 32 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 55 / 1100989 | 49 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 23 / 211054 | 108 | |
| heart | 9 / 89626 | 100 | |
| intestine | 19 / 234472 | 81 | |
| kidney | 15 / 211777 | 70 | |
| larynx | 0 / 24145 | 0 | |
| liver | 7 / 207743 | 33 | |
| lung | 38 / 336974 | 112 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 11 / 91610 | 120 | |
| mammary gland | 11 / 153271 | 71 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 10 / 102051 | 97 | |
| pancreas | 15 / 214812 | 69 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 24 / 280825 | 85 | |
| prostate | 28 / 189345 | 147 | |
| salivary gland | 6 / 20155 | 297 | |
| skin | 24 / 210574 | 113 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 0 / 96619 | 0 | |
| testis | 9 / 330442 | 27 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 3 / 13680 | 219 | |
| uterus | 26 / 232878 | 111 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218057_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 115.35 | |
| Adipocyte | 8.45 |  |
| AdrenalCortex | 5.25 | |
| Adrenalgland | 4.8 | |
| Amygdala | 6.7 | |
| Appendix | 4.05 | |
| AtrioventricularNode | 2.95 | |
| BDCA4+_DentriticCells | 43.7 | |
| Bonemarrow | 5 | |
| BronchialEpithelialCells | 56.4 | |
| CD105+_Endothelial | 40.55 | |
| CD14+_Monocytes | 51.55 | |
| CD19+_BCells(neg._sel.) | 29.6 | |
| CD33+_Myeloid | 59.5 | |
| CD34+ | 62.35 | |
| CD4+_Tcells | 20.05 | |
| CD56+_NKCells | 44.25 | |
| CD71+_EarlyErythroid | 11.95 | |
| CD8+_Tcells | 18.2 | |
| CardiacMyocytes | 18.6 | |
| Caudatenucleus | 4.3 | |
| Cerebellum | 6.95 | |
| CerebellumPeduncles | 5.9 | |
| CiliaryGanglion | 3.65 | |
| CingulateCortex | 5.3 | |
| Colorectaladenocarcinoma | 18.05 | |
| DorsalRootGanglion | 3.8 | |
| FetalThyroid | 5.05 | |
| Fetalbrain | 5.65 | |
| Fetalliver | 3.2 | |
| Fetallung | 5.45 | |
| GlobusPallidus | 3.3 | |
| Heart | 14.15 | |
| Hypothalamus | 6.8 | |
| Kidney | 4 | |
| Leukemia_chronicMyelogenousK-562 | 54.65 | |
| Leukemia_promyelocytic-HL-60 | 21.8 | |
| Leukemialymphoblastic(MOLT-4) | 21.55 | |
| Liver | 6.55 | |
| Lung | 24.8 | |
| Lymphnode | 4.5 | |
| Lymphoma_burkitts(Daudi) | 32.35 | |
| Lymphoma_burkitts(Raji) | 40.7 | |
| MedullaOblongata | 4.5 | |
| OccipitalLobe | 5.05 | |
| OlfactoryBulb | 4.5 | |
| Ovary | 2.5 | |
| Pancreas | 3.5 | |
| PancreaticIslet | 4.55 | |
| ParietalLobe | 6.2 | |
| Pituitary | 6.6 | |
| Placenta | 17.4 | |
| Pons | 3.85 | |
| PrefrontalCortex | 6 | |
| Prostate | 17.7 | |
| Salivarygland | 3.8 | |
| SkeletalMuscle | 6 | |
| Skin | 3.3 | |
| SmoothMuscle | 25.2 | |
| Spinalcord | 6.95 | |
| SubthalamicNucleus | 4.05 | |
| SuperiorCervicalGanglion | 4.8 | |
| TemporalLobe | 4.35 | |
| Testis | 25.3 | |
| TestisGermCell | 7.35 | |
| TestisIntersitial | 12.7 | |
| TestisLeydigCell | 12.5 | |
| TestisSeminiferousTubule | 6.9 | |
| Thalamus | 5.35 | |
| Thymus | 19.5 | |
| Thyroid | 9.35 | |
| Tongue | 4.55 | |
| Tonsil | 5.05 | |
| Trachea | 3.55 | |
| TrigeminalGanglion | 4.5 | |
| Uterus | 6.4 | |
| UterusCorpus | 5.1 | |
| WholeBlood | 5 | |
| Wholebrain | 21.1 | |
| colon | 13.4 | |
| pineal_day | 21.28 | |
| pineal_night | 16.82 | |
| retina | 15.275 | |
| small_intestine | 9.1 | |
- Probe name: A_23_P106859
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.85 ± 0.27 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.81 ± 0.14 | |
| Basal Part of Pons | 9.03 ± 0.21 | |
| Cerebellar Cortex | 8.99 ± 0.21 | |
| Cerebellar Nuclei | 9.18 ± 0.24 | |
| Claustrum | 8.74 ± 0.25 | |
| Epithalamus | 9.07 ± 0.28 | |
| Frontal Lobe | 9.15 ± 0.22 | |
| Globus Pallidus | 8.95 ± 0.25 | |
| Hypothalamus | 9.03 ± 0.17 | |
| Insula | 9.23 ± 0.27 | |
| Limbic Lobe | 9.05 ± 0.32 | |
| Mesencephalon | 8.98 ± 0.26 | |
| Myelencephalon | 9 ± 0.27 | |
| Occipital Lobe | 8.78 ± 0.22 | |
| Parietal Lobe | 9 ± 0.26 | |
| Pontine Tegmentum | 9.06 ± 0.26 | |
| Striatum | 8.96 ± 0.24 | |
| Subthalamus | 9.02 ± 0.37 | |
| Temporal Lobe | 9.09 ± 0.24 | |
| Thalamus | 8.95 ± 0.2 | |
| White Matter | 9.06 ± 0.15 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cox4nb | CB | Cerebellum | 16.77 | |
| 16.85 | | |||
| Cox4nb | CTX | Cerebral cortex | 24 | |
| 7.94 | | |||
| Cox4nb | HIP | Hippocampal region | 16.71 | |
| 12.24 | | |||
| Cox4nb | HPF | Hippocampal formation | 15.87 | |
| 8.99 | | |||
| Cox4nb | HY | Hypothalamus | 21.92 | |
| 6.76 | | |||
| Cox4nb | LSX | Lateral septal complex | 14.91 | |
| 3.8 | | |||
| Cox4nb | MB | Midbrain | 21.88 | |
| 9.52 | | |||
| Cox4nb | MY | Medulla | 41.03 | |
| 22.21 | | |||
| Cox4nb | OLF | Olfactory bulb | 18.01 | |
| 7.87 | | |||
| Cox4nb | P | Pons | 32.12 | |
| 16.1 | | |||
| Cox4nb | PAL | Pallidum | 17.43 | |
| 6.49 | | |||
| Cox4nb | RHP | Retrohippocampal region | 14.6 | |
| 4.59 | | |||
| Cox4nb | sAMY | Striatum-like amygdalar nuclei | 8.07 | |
| 2.58 | | |||
| Cox4nb | STR | Striatum | 13.13 | |
| 3.98 | | |||
| Cox4nb | STRd | Striatum dorsal region | 12.99 | |
| 3.79 | | |||
| Cox4nb | STRv | Striatum ventral region | 16.67 | |
| 5.72 | | |||
| Cox4nb | TH | Thalamus | 19.46 | |
| 7.05 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| CX4NB_HUMAN_2 | 10 | 2 | 11 | PGVKLTTQAY | PRIDE |
| PAp00009021 | 14 | 21 | 34 | YPHCAVNGLLVAEK | Peptide Atlas |