AutismKB 2.0

Annotation Detail for ABCA7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ABCA7 ( ABCA-SSN,ABCX,FLJ40025 )
Gene Full Name: ATP-binding cassette, sub-family A (ABC1), member 7
Band: 19p13.3
Quick LinksEntrez ID:10347; OMIM: 605414; Uniprot ID:ABCA7_HUMAN; ENSEMBL ID: ENSG00000064687; HGNC ID: 37
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia18 / 95842187
liver tumor0 / 963590 
lung tumor9 / 10312787
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal51 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone1 / 7165513
bone marrow1 / 4880120
brain7 / 11009896
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung14 / 33697441
lymph0 / 442700 
lymph node12 / 91610130
mammary gland8 / 15327152
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate7 / 18934536
salivary gland0 / 201550 
skin2 / 2105749
spleen4 / 5395274
stomach2 / 9661920
testis2 / 3304426
thymus11 / 81131135
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219577_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.45
Adipocyte8.25
AdrenalCortex8.65
Adrenalgland6.8
Amygdala8.5
Appendix8.05
AtrioventricularNode6.15
BDCA4+_DentriticCells107.8
Bonemarrow9.3
BronchialEpithelialCells7.85
CD105+_Endothelial69.05
CD14+_Monocytes34.75
CD19+_BCells(neg._sel.)58.15
CD33+_Myeloid23.25
CD34+35.9
CD4+_Tcells121.65
CD56+_NKCells48.55
CD71+_EarlyErythroid102.95
CD8+_Tcells131.8
CardiacMyocytes10.5
Caudatenucleus7.2
Cerebellum6.65
CerebellumPeduncles9.6
CiliaryGanglion5.6
CingulateCortex9.65
Colorectaladenocarcinoma16
DorsalRootGanglion6.2
FetalThyroid7.85
Fetalbrain8.15
Fetalliver7.2
Fetallung6.75
GlobusPallidus6.1
Heart10.95
Hypothalamus8
Kidney6.55
Leukemia_chronicMyelogenousK-5627.75
Leukemia_promyelocytic-HL-607.4
Leukemialymphoblastic(MOLT-4)7.1
Liver11.05
Lung13.55
Lymphnode11.95
Lymphoma_burkitts(Daudi)12.05
Lymphoma_burkitts(Raji)27.05
MedullaOblongata6.85
OccipitalLobe7.15
OlfactoryBulb6.3
Ovary5.35
Pancreas6.55
PancreaticIslet8.85
ParietalLobe9
Pituitary9.5
Placenta8.5
Pons7.85
PrefrontalCortex10.2
Prostate13.4
Salivarygland7.1
SkeletalMuscle12
Skin6.75
SmoothMuscle8.95
Spinalcord8.7
SubthalamicNucleus7.6
SuperiorCervicalGanglion9.15
TemporalLobe7.5
Testis6.85
TestisGermCell6.7
TestisIntersitial6.7
TestisLeydigCell8
TestisSeminiferousTubule6.4
Thalamus10.35
Thymus9.35
Thyroid10.4
Tongue11.2
Tonsil9.45
Trachea6.9
TrigeminalGanglion7.9
Uterus6.6
UterusCorpus7.35
WholeBlood34.15
Wholebrain6.7
colon8.2
pineal_day185.22
pineal_night148.82
retina23.6
small_intestine7.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16171_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 1.08
Basal Forebrain1.88 ± 0.42
Basal Part of Pons1.88 ± 0.62
Cerebellar Cortex2.07 ± 0.66
Cerebellar Nuclei2.06 ± 0.67
Claustrum2.47 ± 0.79
Epithalamus1.56 ± 0.71
Frontal Lobe1.79 ± 0.67
Globus Pallidus2.03 ± 0.5
Hypothalamus1.81 ± 0.52
Insula1.48 ± 0.48
Limbic Lobe1.85 ± 0.61
Mesencephalon1.97 ± 0.71
Myelencephalon1.92 ± 0.62
Occipital Lobe1.84 ± 0.74
Parietal Lobe1.86 ± 0.63
Pontine Tegmentum1.78 ± 0.63
Striatum1.71 ± 0.53
Subthalamus1.98 ± 0.66
Temporal Lobe1.78 ± 0.66
Thalamus1.82 ± 0.61
White Matter1.98 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abca7CBCerebellum11.74
10.71
Abca7CTXCerebral cortex2.22
1.81
Abca7HIPHippocampal region1.69
1.46
Abca7HPFHippocampal formation1.45
1.21
Abca7HYHypothalamus1
1.09
Abca7LSXLateral septal complex0.68
0.57
Abca7MBMidbrain2.93
2.69
Abca7MYMedulla15.36
14.59
Abca7OLFOlfactory bulb4.37
2.81
Abca7PPons10.61
9.82
Abca7PALPallidum3.15
2.59
Abca7RHPRetrohippocampal region1.09
0.89
Abca7sAMYStriatum-like amygdalar nuclei1.03
0.84
Abca7STRStriatum1.54
1.17
Abca7STRdStriatum dorsal region1.48
1.13
Abca7STRvStriatum ventral region2.25
1.58
Abca7THThalamus4.05
2.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved