AutismKB 2.0

Annotation Detail for HMG20B


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Basic Information Top
Gene Symbol:HMG20B ( BRAF25,BRAF35,FLJ26127,HMGX2,HMGXB2,PP7706,SMARCE1r,SOXL,pp8857 )
Gene Full Name: high-mobility group 20B
Band: 19p13.3
Quick LinksEntrez ID:10362; OMIM: 605535; Uniprot ID:HM20B_HUMAN; ENSEMBL ID: ENSG00000064961; HGNC ID: 5002
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst6 / 6231996
fetus36 / 56401263
neonate1 / 3109732
infant1 / 2362042
juvenile3 / 5555653
adult155 / 193912179
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor4 / 34366116
chondrosarcoma20 / 82823241
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor25 / 119369209
germ cell tumor26 / 26384598
glioma15 / 106883140
head and neck tumor8 / 13630258
kidney tumor10 / 68959145
leukemia4 / 9584241
liver tumor14 / 96359145
lung tumor11 / 103127106
lymphoma7 / 7175597
non-neoplasia4 / 9725041
normal196 / 336030758
ovarian tumor6 / 7668278
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer33 / 102680321
retinoblastoma2 / 4635643
skin tumor84 / 124949672
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland4 / 33197120
ascites17 / 40015424
bladder0 / 297570 
blood3 / 12347824
bone17 / 71655237
bone marrow1 / 4880120
brain36 / 110098932
cervix4 / 4817183
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye46 / 211054217
heart2 / 8962622
intestine17 / 23447272
kidney23 / 211777108
larynx1 / 2414541
liver20 / 20774396
lung47 / 336974139
lymph5 / 44270112
lymph node6 / 9161065
mammary gland19 / 153271123
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary11 / 102051107
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta18 / 28082564
prostate39 / 189345205
salivary gland6 / 20155297
skin94 / 210574446
spleen3 / 5395255
stomach8 / 9661982
testis14 / 33044242
thymus6 / 8113173
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord1 / 1368073
uterus31 / 232878133
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210719_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.1
Adipocyte6.7
AdrenalCortex4.4
Adrenalgland5.2
Amygdala4.65
Appendix4.25
AtrioventricularNode3.2
BDCA4+_DentriticCells29
Bonemarrow4.5
BronchialEpithelialCells10.3
CD105+_Endothelial22.35
CD14+_Monocytes28.95
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid35.15
CD34+46.6
CD4+_Tcells15.7
CD56+_NKCells20.15
CD71+_EarlyErythroid7.6
CD8+_Tcells13.2
CardiacMyocytes11.6
Caudatenucleus3.8
Cerebellum3.45
CerebellumPeduncles4.75
CiliaryGanglion2.9
CingulateCortex4.25
Colorectaladenocarcinoma17.95
DorsalRootGanglion3.2
FetalThyroid4.25
Fetalbrain4.25
Fetalliver3.75
Fetallung9.7
GlobusPallidus3.1
Heart9.2
Hypothalamus4.7
Kidney16.15
Leukemia_chronicMyelogenousK-56214.2
Leukemia_promyelocytic-HL-6017.5
Leukemialymphoblastic(MOLT-4)26.8
Liver5.75
Lung24.35
Lymphnode6.4
Lymphoma_burkitts(Daudi)6.05
Lymphoma_burkitts(Raji)61.3
MedullaOblongata4.25
OccipitalLobe3.7
OlfactoryBulb6.75
Ovary2.65
Pancreas3.3
PancreaticIslet4.5
ParietalLobe4.45
Pituitary4.8
Placenta53.5
Pons4.1
PrefrontalCortex5.5
Prostate143.2
Salivarygland3.35
SkeletalMuscle4.85
Skin3.25
SmoothMuscle5.65
Spinalcord5.75
SubthalamicNucleus3.85
SuperiorCervicalGanglion4.75
TemporalLobe3.85
Testis9.55
TestisGermCell7.4
TestisIntersitial4.85
TestisLeydigCell4.2
TestisSeminiferousTubule3.75
Thalamus3.6
Thymus85.05
Thyroid45.75
Tongue4.15
Tonsil4.25
Trachea9.65
TrigeminalGanglion4.15
Uterus14.2
UterusCorpus3.85
WholeBlood15.5
Wholebrain3.6
colon43.35
pineal_day5.34
pineal_night5.22
retina11.875
small_intestine20.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9512_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.38 ± 0.39
Basal Forebrain6.79 ± 0.46
Basal Part of Pons6.48 ± 0.52
Cerebellar Cortex5.9 ± 0.25
Cerebellar Nuclei6.81 ± 0.4
Claustrum6.82 ± 0.31
Epithalamus6.83 ± 0.25
Frontal Lobe6.23 ± 0.55
Globus Pallidus7.85 ± 0.28
Hypothalamus6.37 ± 0.42
Insula6.08 ± 0.38
Limbic Lobe6.13 ± 0.67
Mesencephalon6.55 ± 0.52
Myelencephalon6.48 ± 0.47
Occipital Lobe6.35 ± 0.48
Parietal Lobe6.31 ± 0.53
Pontine Tegmentum6.34 ± 0.58
Striatum6.8 ± 0.61
Subthalamus6.67 ± 0.1
Temporal Lobe6.22 ± 0.49
Thalamus6.66 ± 0.42
White Matter8.36 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hmg20bCBCerebellum8.63
11.57
Hmg20bCTXCerebral cortex12.1
9.82
Hmg20bHIPHippocampal region16.52
15.77
Hmg20bHPFHippocampal formation15.22
13.47
Hmg20bHYHypothalamus10.81
10.91
Hmg20bLSXLateral septal complex0.52
0.45
Hmg20bMBMidbrain5.76
6.97
Hmg20bMYMedulla12.05
16.55
Hmg20bOLFOlfactory bulb23.04
19.29
Hmg20bPPons14.75
20.18
Hmg20bPALPallidum10.51
10.74
Hmg20bRHPRetrohippocampal region12.69
9.96
Hmg20bsAMYStriatum-like amygdalar nuclei15.34
13.9
Hmg20bSTRStriatum7.11
5.88
Hmg20bSTRdStriatum dorsal region4.08
3.46
Hmg20bSTRvStriatum ventral region16.84
12.32
Hmg20bTHThalamus10
8.44
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HM20B_HUMAN_245 12 245 256 TLALQQQLQAVR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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