AutismKB 2.0

Annotation Detail for CDR2


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Basic Information Top
Gene Symbol:CDR2 ( CDR62,Yo )
Gene Full Name: cerebellar degeneration-related protein 2, 62kDa
Band: 16p12.2
Quick LinksEntrez ID:1039; OMIM: 117340; Uniprot ID:CDR2_HUMAN; ENSEMBL ID: ENSG00000140743; HGNC ID: 1799
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult71 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal117 / 336030734
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow1 / 4880120
brain17 / 110098915
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye17 / 21105480
heart4 / 8962644
intestine15 / 23447263
kidney8 / 21177737
larynx0 / 241450 
liver6 / 20774328
lung12 / 33697435
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta7 / 28082524
prostate6 / 18934531
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach3 / 9661931
testis27 / 33044281
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209501_at
Cell line Expression level Expression bar
721_B_lymphoblasts32.95
Adipocyte9.3
AdrenalCortex8.55
Adrenalgland9.2
Amygdala10.2
Appendix9.45
AtrioventricularNode6.4
BDCA4+_DentriticCells10.8
Bonemarrow8.1
BronchialEpithelialCells9.25
CD105+_Endothelial9.5
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)9.95
CD33+_Myeloid10
CD34+10.1
CD4+_Tcells70.95
CD56+_NKCells11.3
CD71+_EarlyErythroid8.8
CD8+_Tcells63.25
CardiacMyocytes10.75
Caudatenucleus10.7
Cerebellum6.65
CerebellumPeduncles8.3
CiliaryGanglion6.4
CingulateCortex8.4
Colorectaladenocarcinoma8.05
DorsalRootGanglion6.95
FetalThyroid9.2
Fetalbrain7.95
Fetalliver8.1
Fetallung8.05
GlobusPallidus5.95
Heart9.7
Hypothalamus10.45
Kidney7.5
Leukemia_chronicMyelogenousK-5628.6
Leukemia_promyelocytic-HL-6011.75
Leukemialymphoblastic(MOLT-4)11.35
Liver11.2
Lung10.15
Lymphnode15.7
Lymphoma_burkitts(Daudi)19.35
Lymphoma_burkitts(Raji)13.15
MedullaOblongata8.75
OccipitalLobe7.7
OlfactoryBulb6.25
Ovary4.8
Pancreas7.5
PancreaticIslet12.5
ParietalLobe8.9
Pituitary24.55
Placenta6.9
Pons9.75
PrefrontalCortex11.85
Prostate12
Salivarygland10.15
SkeletalMuscle10.45
Skin6.85
SmoothMuscle16.1
Spinalcord9.4
SubthalamicNucleus8.45
SuperiorCervicalGanglion10.6
TemporalLobe8.55
Testis56.85
TestisGermCell37.6
TestisIntersitial67.3
TestisLeydigCell25.65
TestisSeminiferousTubule44.8
Thalamus9.5
Thymus13.75
Thyroid44.8
Tongue7.65
Tonsil9
Trachea11.6
TrigeminalGanglion8.75
Uterus16.2
UterusCorpus7.9
WholeBlood9.2
Wholebrain8.25
colon13.3
pineal_day18.96
pineal_night21.16
retina61.575
small_intestine39.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P339071
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.58 ± 0.4
Basal Forebrain4.39 ± 0.62
Basal Part of Pons5.46 ± 0.46
Cerebellar Cortex4.67 ± 0.45
Cerebellar Nuclei4.43 ± 0.6
Claustrum3.95 ± 0.84
Epithalamus4.63 ± 0.77
Frontal Lobe4.87 ± 0.54
Globus Pallidus3.83 ± 0.4
Hypothalamus4.98 ± 0.74
Insula4.59 ± 0.73
Limbic Lobe4.62 ± 0.69
Mesencephalon4.83 ± 0.59
Myelencephalon4.69 ± 0.71
Occipital Lobe4.64 ± 0.56
Parietal Lobe4.82 ± 0.68
Pontine Tegmentum4.85 ± 0.58
Striatum5.64 ± 0.46
Subthalamus5.21 ± 0.38
Temporal Lobe4.83 ± 0.61
Thalamus4.93 ± 0.57
White Matter3.05 ± 0.64
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdr2CBCerebellum21.83
46.08
Cdr2CTXCerebral cortex6.33
5.83
Cdr2HIPHippocampal region1.95
2.63
Cdr2HPFHippocampal formation1.8
1.94
Cdr2HYHypothalamus3.88
3.83
Cdr2LSXLateral septal complex0.7
0.56
Cdr2MBMidbrain13.99
17.14
Cdr2MYMedulla26.89
41.64
Cdr2OLFOlfactory bulb7.06
6.76
Cdr2PPons19.82
28.9
Cdr2PALPallidum4.16
4.26
Cdr2RHPRetrohippocampal region1.63
1.17
Cdr2sAMYStriatum-like amygdalar nuclei4.74
5.34
Cdr2STRStriatum2.04
2
Cdr2STRdStriatum dorsal region1.78
1.67
Cdr2STRvStriatum ventral region1.36
0.98
Cdr2THThalamus11.76
11.72
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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