AutismKB 2.0

Annotation Detail for DLC1


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Basic Information Top
Gene Symbol:DLC1 ( ARHGAP7,FLJ21120,HP,STARD12,p122-RhoGAP )
Gene Full Name: deleted in liver cancer 1
Band: 8p22
Quick LinksEntrez ID:10395; OMIM: 604258; Uniprot ID:RHG07_HUMAN; ENSEMBL ID: ENSG00000164741; HGNC ID: 2897
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst0 / 623190 
fetus66 / 564012117
neonate2 / 3109764
infant0 / 236200 
juvenile4 / 5555671
adult123 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma19 / 82823229
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor9 / 9635993
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal271 / 336030780
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor10 / 12494980
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue8 / 13106610
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone10 / 71655139
bone marrow3 / 4880161
brain39 / 110098935
cervix0 / 481710 
connective tissue22 / 149255147
ear3 / 16212185
embryonic tissue25 / 215722115
esophagus0 / 202090 
eye18 / 21105485
heart16 / 89626178
intestine6 / 23447225
kidney9 / 21177742
larynx1 / 2414541
liver12 / 20774357
lung57 / 336974169
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth0 / 670520 
muscle4 / 10771537
nerve1 / 1576863
ovary2 / 10205119
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta14 / 28082549
prostate4 / 18934521
salivary gland0 / 201550 
skin26 / 210574123
spleen5 / 5395292
stomach2 / 9661920
testis13 / 33044239
thymus2 / 8113124
thyroid6 / 47473126
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus15 / 23287864
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210762_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.65
Adipocyte23.9
AdrenalCortex20.25
Adrenalgland12.65
Amygdala13.8
Appendix18.1
AtrioventricularNode9.45
BDCA4+_DentriticCells9.1
Bonemarrow12.05
BronchialEpithelialCells8.1
CD105+_Endothelial48.55
CD14+_Monocytes8.85
CD19+_BCells(neg._sel.)8.75
CD33+_Myeloid13.35
CD34+77.75
CD4+_Tcells9
CD56+_NKCells9.85
CD71+_EarlyErythroid88.2
CD8+_Tcells8
CardiacMyocytes35.35
Caudatenucleus18.05
Cerebellum9.15
CerebellumPeduncles11.75
CiliaryGanglion8.95
CingulateCortex13.5
Colorectaladenocarcinoma10.25
DorsalRootGanglion12.15
FetalThyroid27.25
Fetalbrain9.85
Fetalliver32.2
Fetallung193.45
GlobusPallidus9
Heart15.95
Hypothalamus13.65
Kidney9.95
Leukemia_chronicMyelogenousK-5628.15
Leukemia_promyelocytic-HL-608
Leukemialymphoblastic(MOLT-4)6.6
Liver18.85
Lung373.4
Lymphnode9.05
Lymphoma_burkitts(Daudi)10.9
Lymphoma_burkitts(Raji)14.5
MedullaOblongata18.2
OccipitalLobe15.75
OlfactoryBulb56.05
Ovary8.1
Pancreas9.3
PancreaticIslet11.25
ParietalLobe13.15
Pituitary14.65
Placenta48.6
Pons11.95
PrefrontalCortex34.1
Prostate14.5
Salivarygland9.8
SkeletalMuscle11.2
Skin10.1
SmoothMuscle305.4
Spinalcord13.15
SubthalamicNucleus11.25
SuperiorCervicalGanglion13.8
TemporalLobe15.8
Testis13.7
TestisGermCell10.45
TestisIntersitial15.75
TestisLeydigCell10.4
TestisSeminiferousTubule10.2
Thalamus12.5
Thymus9.55
Thyroid15.75
Tongue12
Tonsil8
Trachea10.2
TrigeminalGanglion12.1
Uterus60.05
UterusCorpus11.1
WholeBlood9
Wholebrain25.25
colon12.75
pineal_day14.48
pineal_night16.72
retina70.325
small_intestine44.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16159_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.16 ± 0.49
Basal Forebrain6.51 ± 0.31
Basal Part of Pons6.09 ± 0.6
Cerebellar Cortex5.67 ± 0.34
Cerebellar Nuclei7.25 ± 0.35
Claustrum6.38 ± 0.49
Epithalamus5.55 ± 0.72
Frontal Lobe6.31 ± 0.61
Globus Pallidus7.83 ± 0.36
Hypothalamus5.53 ± 0.69
Insula6.22 ± 0.22
Limbic Lobe6.41 ± 0.97
Mesencephalon6.46 ± 0.66
Myelencephalon6.42 ± 0.64
Occipital Lobe6.45 ± 0.78
Parietal Lobe6.25 ± 0.61
Pontine Tegmentum6.56 ± 0.49
Striatum7.08 ± 0.48
Subthalamus6.54 ± 0.39
Temporal Lobe6.1 ± 0.55
Thalamus6.56 ± 0.41
White Matter8.45 ± 0.45
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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