AutismKB 2.0

Annotation Detail for ADARB1


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Basic Information Top
Gene Symbol:ADARB1 ( ADAR2,DRABA2,DRADA2,RED1 )
Gene Full Name: adenosine deaminase, RNA-specific, B1
Band: 21q22.3
Quick LinksEntrez ID:104; OMIM: 601218; Uniprot ID:RED1_HUMAN; ENSEMBL ID: ENSG00000197381; HGNC ID: 226
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma4 / 10688337
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal141 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone6 / 7165583
bone marrow0 / 488010 
brain38 / 110098934
cervix2 / 4817141
connective tissue7 / 14925546
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye9 / 21105442
heart7 / 8962678
intestine5 / 23447221
kidney6 / 21177728
larynx0 / 241450 
liver7 / 20774333
lung15 / 33697444
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth3 / 6705244
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate10 / 18934552
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203865_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.25
Adipocyte19.7
AdrenalCortex5.55
Adrenalgland4.5
Amygdala22.9
Appendix5.4
AtrioventricularNode4
BDCA4+_DentriticCells7.15
Bonemarrow5.25
BronchialEpithelialCells4.95
CD105+_Endothelial5.5
CD14+_Monocytes5.3
CD19+_BCells(neg._sel.)41.55
CD33+_Myeloid6.85
CD34+10.3
CD4+_Tcells24.05
CD56+_NKCells6.65
CD71+_EarlyErythroid4.95
CD8+_Tcells22.55
CardiacMyocytes6.65
Caudatenucleus17.3
Cerebellum38.3
CerebellumPeduncles66.25
CiliaryGanglion3.8
CingulateCortex14.35
Colorectaladenocarcinoma11.15
DorsalRootGanglion4.1
FetalThyroid5.2
Fetalbrain16.55
Fetalliver4.55
Fetallung16.95
GlobusPallidus6.2
Heart6.7
Hypothalamus34.9
Kidney4.3
Leukemia_chronicMyelogenousK-5624.65
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.5
Liver7.05
Lung59.7
Lymphnode6.95
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)7.45
MedullaOblongata9.25
OccipitalLobe11.5
OlfactoryBulb4.3
Ovary3.5
Pancreas4.15
PancreaticIslet5.7
ParietalLobe11.1
Pituitary6.15
Placenta5.65
Pons6.5
PrefrontalCortex18.45
Prostate7.45
Salivarygland4.2
SkeletalMuscle6.15
Skin4.1
SmoothMuscle5.95
Spinalcord5.8
SubthalamicNucleus15.05
SuperiorCervicalGanglion5.95
TemporalLobe7
Testis4.55
TestisGermCell4.35
TestisIntersitial4.25
TestisLeydigCell5.35
TestisSeminiferousTubule4.45
Thalamus44.8
Thymus4.35
Thyroid6.4
Tongue5.15
Tonsil5.2
Trachea4.45
TrigeminalGanglion5.3
Uterus19.4
UterusCorpus4.8
WholeBlood5.75
Wholebrain26.65
colon6
pineal_day38.86
pineal_night32.76
retina14.9
small_intestine5.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P361336
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.9 ± 0.78
Basal Forebrain4.16 ± 0.48
Basal Part of Pons4.77 ± 0.39
Cerebellar Cortex4.78 ± 0.31
Cerebellar Nuclei4.49 ± 0.64
Claustrum3.46 ± 0.85
Epithalamus3.21 ± 0.68
Frontal Lobe4.21 ± 0.69
Globus Pallidus2.76 ± 0.66
Hypothalamus3.69 ± 0.34
Insula4.41 ± 0.18
Limbic Lobe4.27 ± 0.73
Mesencephalon3.96 ± 0.65
Myelencephalon4.08 ± 0.69
Occipital Lobe4.36 ± 0.52
Parietal Lobe4.21 ± 0.65
Pontine Tegmentum4.05 ± 0.61
Striatum3.94 ± 0.59
Subthalamus3.65 ± 0.17
Temporal Lobe4.21 ± 0.52
Thalamus4.38 ± 0.64
White Matter1.76 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adarb1CBCerebellum49.75
66.77
Adarb1CTXCerebral cortex31.97
25.05
Adarb1HIPHippocampal region21.65
24.78
Adarb1HPFHippocampal formation24.08
24.25
Adarb1HYHypothalamus6.29
5.96
Adarb1LSXLateral septal complex5.86
4.08
Adarb1MBMidbrain20.56
21.29
Adarb1MYMedulla40.65
52.8
Adarb1OLFOlfactory bulb45
45.76
Adarb1PPons30.58
38.19
Adarb1PALPallidum14.6
16.05
Adarb1RHPRetrohippocampal region29.31
24.59
Adarb1sAMYStriatum-like amygdalar nuclei9.98
7.7
Adarb1STRStriatum9.17
7.5
Adarb1STRdStriatum dorsal region7.44
6.06
Adarb1STRvStriatum ventral region15.57
12.66
Adarb1THThalamus97.01
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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