AutismKB 2.0

Annotation Detail for IFITM3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IFITM3 ( 1-8U,IP15 )
Gene Full Name: interferon induced transmembrane protein 3 (1-8U)
Band: 11p15.5
Quick LinksEntrez ID:10410; OMIM: 605579; Uniprot ID:IFM3_HUMAN; ENSEMBL ID: ENSG00000142089; HGNC ID: 5414
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst11 / 62319176
fetus66 / 564012117
neonate6 / 31097192
infant2 / 2362084
juvenile2 / 5555635
adult501 / 1939121258
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma2 / 17475114
breast (mammary gland) tumor17 / 94178180
cervical tumor16 / 34366465
chondrosarcoma21 / 82823253
colorectal tumor19 / 114246166
esophageal tumor3 / 17290173
gastrointestinal tumor49 / 119369410
germ cell tumor12 / 26384545
glioma16 / 106883149
head and neck tumor36 / 136302264
kidney tumor11 / 68959159
leukemia10 / 95842104
liver tumor36 / 96359373
lung tumor13 / 103127126
lymphoma0 / 717550 
non-neoplasia10 / 97250102
normal567 / 3360307168
ovarian tumor31 / 76682404
pancreatic tumor49 / 104616468
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer13 / 102680126
retinoblastoma0 / 463560 
skin tumor29 / 124949232
soft tissue/muscle tissue tumor21 / 125191167
uterine tumor35 / 90257387
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue8 / 13106610
adrenal gland12 / 33197361
ascites17 / 40015424
bladder1 / 2975733
blood16 / 123478129
bone16 / 71655223
bone marrow23 / 48801471
brain86 / 110098978
cervix17 / 48171352
connective tissue21 / 149255140
ear6 / 16212370
embryonic tissue46 / 215722213
esophagus3 / 20209148
eye51 / 211054241
heart29 / 89626323
intestine39 / 234472166
kidney20 / 21177794
larynx10 / 24145414
liver69 / 207743332
lung61 / 336974181
lymph0 / 442700 
lymph node0 / 916100 
mammary gland24 / 153271156
mouth14 / 67052208
muscle9 / 10771583
nerve1 / 1576863
ovary41 / 102051401
pancreas54 / 214812251
parathyroid4 / 20539194
pharynx9 / 41328217
pituitary gland3 / 16585180
placenta38 / 280825135
prostate51 / 189345269
salivary gland6 / 20155297
skin45 / 210574213
spleen7 / 53952129
stomach45 / 96619465
testis20 / 33044260
thymus3 / 8113136
thyroid13 / 47473273
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord6 / 13680438
uterus77 / 232878330
vascular16 / 51780308
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212203_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts129
Adipocyte1903.5
AdrenalCortex609.3
Adrenalgland1006.5
Amygdala226.35
Appendix1351.6
AtrioventricularNode902.95
BDCA4+_DentriticCells244.75
Bonemarrow724.1
BronchialEpithelialCells919
CD105+_Endothelial155.9
CD14+_Monocytes721.3
CD19+_BCells(neg._sel.)239.85
CD33+_Myeloid688.45
CD34+297.65
CD4+_Tcells431.4
CD56+_NKCells1187.6
CD71+_EarlyErythroid5.9
CD8+_Tcells375.3
CardiacMyocytes1429.65
Caudatenucleus197.65
Cerebellum84.45
CerebellumPeduncles128.5
CiliaryGanglion626.45
CingulateCortex117.55
Colorectaladenocarcinoma912.5
DorsalRootGanglion961.05
FetalThyroid1499.05
Fetalbrain123.2
Fetalliver214.7
Fetallung2201.85
GlobusPallidus68.85
Heart2511.55
Hypothalamus561.45
Kidney452.25
Leukemia_chronicMyelogenousK-562527.95
Leukemia_promyelocytic-HL-605.4
Leukemialymphoblastic(MOLT-4)7.2
Liver3524.2
Lung2537.1
Lymphnode835.15
Lymphoma_burkitts(Daudi)8.2
Lymphoma_burkitts(Raji)6.45
MedullaOblongata51.45
OccipitalLobe130.75
OlfactoryBulb2473.55
Ovary2068.35
Pancreas888.6
PancreaticIslet1812.45
ParietalLobe71.3
Pituitary452.2
Placenta1544
Pons88.25
PrefrontalCortex1408.4
Prostate1089.6
Salivarygland222.35
SkeletalMuscle465.95
Skin357.6
SmoothMuscle1475.55
Spinalcord725.5
SubthalamicNucleus152.55
SuperiorCervicalGanglion354.8
TemporalLobe255.15
Testis583.8
TestisGermCell681.1
TestisIntersitial258.25
TestisLeydigCell319.3
TestisSeminiferousTubule661.75
Thalamus376
Thymus728.35
Thyroid1035.3
Tongue326.95
Tonsil544.55
Trachea538.65
TrigeminalGanglion847.9
Uterus1680.1
UterusCorpus1049.8
WholeBlood2560.85
Wholebrain232.55
colon762.45
pineal_day223.5
pineal_night249.64
retina2320.05
small_intestine852.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P87545
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.06 ± 0.23
Basal Forebrain10.47 ± 0.19
Basal Part of Pons9.83 ± 0.29
Cerebellar Cortex9.99 ± 0.17
Cerebellar Nuclei10.97 ± 0.25
Claustrum9.73 ± 0.34
Epithalamus10.87 ± 0.32
Frontal Lobe10.32 ± 0.42
Globus Pallidus11.66 ± 0.36
Hypothalamus10.44 ± 0.6
Insula10.28 ± 0.3
Limbic Lobe10.17 ± 0.54
Mesencephalon10.6 ± 0.42
Myelencephalon10.55 ± 0.5
Occipital Lobe10.7 ± 0.48
Parietal Lobe10.28 ± 0.4
Pontine Tegmentum10.61 ± 0.45
Striatum11.34 ± 0.52
Subthalamus10.96 ± 0.45
Temporal Lobe10.33 ± 0.35
Thalamus10.68 ± 0.33
White Matter10.44 ± 0.92
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ifitm3CBCerebellum1.42
2.27
Ifitm3CTXCerebral cortex1.2
0.91
Ifitm3HIPHippocampal region1.31
1.05
Ifitm3HPFHippocampal formation1.21
0.93
Ifitm3HYHypothalamus1.03
1.15
Ifitm3LSXLateral septal complex0.07
0.1
Ifitm3MBMidbrain3.03
4.15
Ifitm3MYMedulla3.88
3.94
Ifitm3OLFOlfactory bulb1.75
1.37
Ifitm3PPons1.03
1.1
Ifitm3PALPallidum1.11
1.02
Ifitm3RHPRetrohippocampal region1.03
0.8
Ifitm3sAMYStriatum-like amygdalar nuclei0.73
0.62
Ifitm3STRStriatum2.54
2.56
Ifitm3STRdStriatum dorsal region3.53
3.75
Ifitm3STRvStriatum ventral region1.05
0.77
Ifitm3THThalamus0.7
0.54
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
IFM3_HUMAN_1 24 1 24 MNHTVQTFFSPVNSGQPPNYEMLK PRIDE
IFM3_HUMAN_24 25 24 48 EEHEVAVLGAPHNPAPPTSTVIHIR PRIDE
IFM3_HUMAN_88 16 88 103 MVGDVTGAQAYASTAK PRIDE
PAp00075019 16 89 104 MVGDVTGAQAYASTAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved