AutismKB 2.0

Annotation Detail for ZER1


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Basic Information Top
Gene Symbol:ZER1 ( C9orf60,Hzyg,RP11-545E17.4,ZYG,ZYG11BL )
Gene Full Name: zer-1 homolog (C. elegans)
Band: 9q34.11
Quick LinksEntrez ID:10444; OMIM: NA; Uniprot ID:ZER1_HUMAN; ENSEMBL ID: ENSG00000160445; HGNC ID: 30960
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus47 / 56401283
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult107 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor17 / 26384564
glioma21 / 106883196
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal199 / 336030759
ovarian tumor16 / 76682208
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer5 / 10268048
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone4 / 7165555
bone marrow0 / 488010 
brain81 / 110098973
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye13 / 21105461
heart7 / 8962678
intestine17 / 23447272
kidney12 / 21177756
larynx1 / 2414541
liver3 / 20774314
lung11 / 33697432
lymph2 / 4427045
lymph node14 / 91610152
mammary gland14 / 15327191
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary20 / 102051195
pancreas10 / 21481246
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta9 / 28082532
prostate17 / 18934589
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach2 / 9661920
testis31 / 33044293
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202452_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.75
Adipocyte3.55
AdrenalCortex3.85
Adrenalgland3.2
Amygdala5.95
Appendix3.2
AtrioventricularNode2.8
BDCA4+_DentriticCells4.4
Bonemarrow3.75
BronchialEpithelialCells3.05
CD105+_Endothelial3.95
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.2
CD33+_Myeloid4.95
CD34+5.05
CD4+_Tcells4.3
CD56+_NKCells5
CD71+_EarlyErythroid29.8
CD8+_Tcells4.25
CardiacMyocytes4.75
Caudatenucleus4.85
Cerebellum3.2
CerebellumPeduncles6.5
CiliaryGanglion2.65
CingulateCortex4.2
Colorectaladenocarcinoma3.85
DorsalRootGanglion2.85
FetalThyroid3.75
Fetalbrain3.9
Fetalliver3
Fetallung2.9
GlobusPallidus6.1
Heart4.8
Hypothalamus4.3
Kidney3
Leukemia_chronicMyelogenousK-5623.15
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver4.95
Lung4.35
Lymphnode3.05
Lymphoma_burkitts(Daudi)4.75
Lymphoma_burkitts(Raji)4.8
MedullaOblongata3.6
OccipitalLobe4.95
OlfactoryBulb3.05
Ovary2.55
Pancreas3
PancreaticIslet4.05
ParietalLobe4
Pituitary4.5
Placenta4.05
Pons3.65
PrefrontalCortex28.4
Prostate4.6
Salivarygland3
SkeletalMuscle3.85
Skin2.85
SmoothMuscle4.4
Spinalcord4.15
SubthalamicNucleus5.4
SuperiorCervicalGanglion4.2
TemporalLobe3.5
Testis3.45
TestisGermCell3.05
TestisIntersitial3.25
TestisLeydigCell3.75
TestisSeminiferousTubule3.3
Thalamus4.4
Thymus3.15
Thyroid7.9
Tongue3.7
Tonsil3.45
Trachea3.2
TrigeminalGanglion3.7
Uterus3.15
UterusCorpus3.05
WholeBlood4.3
Wholebrain10.8
colon3.85
pineal_day12.68
pineal_night14.42
retina11.7
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P146631
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.18 ± 0.45
Basal Forebrain4.66 ± 0.68
Basal Part of Pons5.41 ± 0.47
Cerebellar Cortex5.1 ± 0.39
Cerebellar Nuclei4.75 ± 0.74
Claustrum5.09 ± 0.41
Epithalamus4.7 ± 0.4
Frontal Lobe5.12 ± 0.4
Globus Pallidus4.1 ± 0.56
Hypothalamus5.19 ± 0.39
Insula5.27 ± 0.41
Limbic Lobe5.18 ± 0.41
Mesencephalon5.01 ± 0.46
Myelencephalon4.99 ± 0.51
Occipital Lobe4.78 ± 0.5
Parietal Lobe5.08 ± 0.42
Pontine Tegmentum5.08 ± 0.53
Striatum4.68 ± 0.53
Subthalamus4.87 ± 0.27
Temporal Lobe5.3 ± 0.41
Thalamus4.83 ± 0.5
White Matter4.93 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zyg11blCBCerebellum44.08
65.63
Zyg11blCTXCerebral cortex93.94
83.35
Zyg11blHIPHippocampal region83.46
100
Zyg11blHPFHippocampal formation85.3
100
Zyg11blHYHypothalamus36.34
32.18
Zyg11blLSXLateral septal complex36.23
29.26
Zyg11blMBMidbrain34.51
32.4
Zyg11blMYMedulla35.63
37.79
Zyg11blOLFOlfactory bulb63.55
59.89
Zyg11blPPons27
27.53
Zyg11blPALPallidum29.93
29.92
Zyg11blRHPRetrohippocampal region90.24
86.41
Zyg11blsAMYStriatum-like amygdalar nuclei54.05
47.04
Zyg11blSTRStriatum38.73
31.54
Zyg11blSTRdStriatum dorsal region35.53
28.85
Zyg11blSTRvStriatum ventral region40.36
30.84
Zyg11blTHThalamus25.27
22.32
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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