AutismKB 2.0

Annotation Detail for FAM3C


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Basic Information Top
Gene Symbol:FAM3C ( ILEI )
Gene Full Name: family with sequence similarity 3, member C
Band: 7q31.31
Quick LinksEntrez ID:10447; OMIM: 608618; Uniprot ID:FAM3C_HUMAN; ENSEMBL ID: ENSG00000196937; HGNC ID: 18664
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus31 / 56401254
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor13 / 26384549
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia3 / 9584231
liver tumor5 / 9635951
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal165 / 336030749
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites4 / 4001599
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow4 / 4880181
brain31 / 110098928
cervix2 / 4817141
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye7 / 21105433
heart3 / 8962633
intestine6 / 23447225
kidney17 / 21177780
larynx0 / 241450 
liver8 / 20774338
lung17 / 33697450
lymph0 / 442700 
lymph node9 / 9161098
mammary gland7 / 15327145
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary5 / 10205148
pancreas4 / 21481218
parathyroid2 / 2053997
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta11 / 28082539
prostate4 / 18934521
salivary gland0 / 201550 
skin16 / 21057475
spleen2 / 5395237
stomach4 / 9661941
testis9 / 33044227
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus13 / 23287855
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201889_at
Cell line Expression level Expression bar
721_B_lymphoblasts94.95
Adipocyte106.6
AdrenalCortex20.3
Adrenalgland30.35
Amygdala649.2
Appendix85.05
AtrioventricularNode14.85
BDCA4+_DentriticCells108.15
Bonemarrow14.1
BronchialEpithelialCells196.45
CD105+_Endothelial28.05
CD14+_Monocytes21.2
CD19+_BCells(neg._sel.)503.75
CD33+_Myeloid22.35
CD34+48
CD4+_Tcells16
CD56+_NKCells196.25
CD71+_EarlyErythroid8.75
CD8+_Tcells33.85
CardiacMyocytes61.3
Caudatenucleus109.65
Cerebellum93.3
CerebellumPeduncles87.2
CiliaryGanglion22.45
CingulateCortex208.1
Colorectaladenocarcinoma106.7
DorsalRootGanglion30.75
FetalThyroid44.5
Fetalbrain376.1
Fetalliver65.05
Fetallung64.3
GlobusPallidus178.35
Heart31.45
Hypothalamus157.65
Kidney26.95
Leukemia_chronicMyelogenousK-56223.7
Leukemia_promyelocytic-HL-60211.6
Leukemialymphoblastic(MOLT-4)20.3
Liver25.1
Lung28.05
Lymphnode107.95
Lymphoma_burkitts(Daudi)217.3
Lymphoma_burkitts(Raji)335.65
MedullaOblongata138.15
OccipitalLobe232.75
OlfactoryBulb76.55
Ovary20.3
Pancreas84.85
PancreaticIslet152.9
ParietalLobe181.5
Pituitary98.8
Placenta123.45
Pons64
PrefrontalCortex618.1
Prostate121.5
Salivarygland49.75
SkeletalMuscle26.85
Skin27
SmoothMuscle143.8
Spinalcord60.95
SubthalamicNucleus152.35
SuperiorCervicalGanglion32.65
TemporalLobe160.7
Testis17.35
TestisGermCell48.4
TestisIntersitial19.25
TestisLeydigCell17.65
TestisSeminiferousTubule19.1
Thalamus178.15
Thymus12.8
Thyroid526.35
Tongue15.5
Tonsil65.45
Trachea176.25
TrigeminalGanglion19.55
Uterus212.65
UterusCorpus36.4
WholeBlood31.7
Wholebrain394.65
colon259.3
pineal_day653.9
pineal_night828.14
retina195.875
small_intestine710.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P157371
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.18 ± 0.51
Basal Forebrain8.94 ± 0.26
Basal Part of Pons10.11 ± 0.14
Cerebellar Cortex9.15 ± 0.2
Cerebellar Nuclei9.08 ± 0.4
Claustrum8.79 ± 0.48
Epithalamus9.06 ± 0.41
Frontal Lobe9.37 ± 0.33
Globus Pallidus8.45 ± 0.49
Hypothalamus9.25 ± 0.43
Insula9.45 ± 0.19
Limbic Lobe9.35 ± 0.44
Mesencephalon9.12 ± 0.48
Myelencephalon9.2 ± 0.54
Occipital Lobe9.4 ± 0.44
Parietal Lobe9.48 ± 0.43
Pontine Tegmentum9.16 ± 0.31
Striatum8.53 ± 0.53
Subthalamus9.62 ± 0.16
Temporal Lobe9.46 ± 0.42
Thalamus9.37 ± 0.41
White Matter8.08 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D6Wsu176eCBCerebellum0.82
1.13
D6Wsu176eCTXCerebral cortex6.82
3.94
D6Wsu176eHIPHippocampal region1.44
1.23
D6Wsu176eHPFHippocampal formation3.64
2.45
D6Wsu176eHYHypothalamus0.65
0.37
D6Wsu176eLSXLateral septal complex0.49
0.64
D6Wsu176eMBMidbrain1.16
0.96
D6Wsu176eMYMedulla0.58
0.46
D6Wsu176eOLFOlfactory bulb10.89
5.35
D6Wsu176ePPons0.49
0.28
D6Wsu176ePALPallidum1.31
0.81
D6Wsu176eRHPRetrohippocampal region6.47
3.74
D6Wsu176esAMYStriatum-like amygdalar nuclei1.05
0.51
D6Wsu176eSTRStriatum0.89
0.61
D6Wsu176eSTRdStriatum dorsal region0.79
0.56
D6Wsu176eSTRvStriatum ventral region1.23
0.81
D6Wsu176eTHThalamus0.33
0.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00030129 13 85 97 ICLEDNVLMSGVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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