AutismKB 2.0

Annotation Detail for CDX2


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Basic Information Top
Gene Symbol:CDX2 ( CDX-3,CDX3 )
Gene Full Name: caudal type homeobox 2
Band: 13q12.2
Quick LinksEntrez ID:1045; OMIM: 600297; Uniprot ID:CDX2_HUMAN; ENSEMBL ID: ENSG00000165556; HGNC ID: 1806
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal3 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine28 / 234472119
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206387_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.8
Adipocyte11.2
AdrenalCortex11.5
Adrenalgland9.35
Amygdala11.6
Appendix11.2
AtrioventricularNode8.4
BDCA4+_DentriticCells11.8
Bonemarrow10.95
BronchialEpithelialCells8.4
CD105+_Endothelial10.95
CD14+_Monocytes12
CD19+_BCells(neg._sel.)12.05
CD33+_Myeloid14.55
CD34+14.35
CD4+_Tcells12.4
CD56+_NKCells13.6
CD71+_EarlyErythroid10.45
CD8+_Tcells11.05
CardiacMyocytes11.5
Caudatenucleus10.05
Cerebellum9.1
CerebellumPeduncles13.25
CiliaryGanglion7.75
CingulateCortex14.85
Colorectaladenocarcinoma11.3
DorsalRootGanglion8.45
FetalThyroid10.95
Fetalbrain11.3
Fetalliver9.75
Fetallung9.45
GlobusPallidus8.8
Heart14
Hypothalamus12.35
Kidney9.35
Leukemia_chronicMyelogenousK-56210.2
Leukemia_promyelocytic-HL-609.9
Leukemialymphoblastic(MOLT-4)9.15
Liver14.25
Lung11.8
Lymphnode9.8
Lymphoma_burkitts(Daudi)14.3
Lymphoma_burkitts(Raji)15.35
MedullaOblongata10.65
OccipitalLobe10.15
OlfactoryBulb9.25
Ovary7.4
Pancreas11.85
PancreaticIslet11.95
ParietalLobe15.95
Pituitary15.7
Placenta11.8
Pons14.45
PrefrontalCortex12.55
Prostate13.25
Salivarygland11.9
SkeletalMuscle16.3
Skin8.45
SmoothMuscle12.8
Spinalcord12.05
SubthalamicNucleus11.3
SuperiorCervicalGanglion12.45
TemporalLobe11.35
Testis9.75
TestisGermCell9.5
TestisIntersitial9.4
TestisLeydigCell11.05
TestisSeminiferousTubule9.7
Thalamus11.4
Thymus8.95
Thyroid13.15
Tongue12.75
Tonsil10.95
Trachea9.45
TrigeminalGanglion10.9
Uterus8.8
UterusCorpus9.9
WholeBlood10.5
Wholebrain9.65
colon11.75
pineal_day13.18
pineal_night12.34
retina9.35
small_intestine10.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15713_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.24 ± 1.1
Basal Forebrain1.7 ± 0.21
Basal Part of Pons1.49 ± 0.55
Cerebellar Cortex1.66 ± 0.83
Cerebellar Nuclei1.97 ± 0.72
Claustrum2.45 ± 0.59
Epithalamus1.43 ± 0.8
Frontal Lobe1.65 ± 0.75
Globus Pallidus2.25 ± 0.43
Hypothalamus1.85 ± 0.74
Insula1.72 ± 0.8
Limbic Lobe1.81 ± 0.72
Mesencephalon1.92 ± 0.7
Myelencephalon1.77 ± 0.71
Occipital Lobe1.69 ± 0.66
Parietal Lobe1.87 ± 0.88
Pontine Tegmentum1.83 ± 0.76
Striatum1.77 ± 0.55
Subthalamus1.87 ± 0.69
Temporal Lobe1.66 ± 0.76
Thalamus1.74 ± 0.7
White Matter2.04 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdx2CBCerebellum3.79
3.96
Cdx2CTXCerebral cortex1.52
1.01
Cdx2HIPHippocampal region0.86
1.55
Cdx2HPFHippocampal formation0.77
1.08
Cdx2HYHypothalamus1.14
1.34
Cdx2LSXLateral septal complex0.49
0.31
Cdx2MBMidbrain0.43
0.44
Cdx2MYMedulla4.17
2.55
Cdx2OLFOlfactory bulb1.23
0.71
Cdx2PPons1.25
0.78
Cdx2PALPallidum0.7
0.4
Cdx2RHPRetrohippocampal region0.61
0.49
Cdx2sAMYStriatum-like amygdalar nuclei0.93
0.52
Cdx2STRStriatum0.6
0.43
Cdx2STRdStriatum dorsal region0.56
0.52
Cdx2STRvStriatum ventral region0.7
0.24
Cdx2THThalamus0.29
0.3
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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