AutismKB 2.0

Annotation Detail for TAB1


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Basic Information Top
Gene Symbol:TAB1 ( 3'-Tab1,MAP3K7IP1,MGC57664 )
Gene Full Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
Band: 22q13.1
Quick LinksEntrez ID:10454; OMIM: 602615; Uniprot ID:TAB1_HUMAN; ENSEMBL ID: ENSG00000100324; HGNC ID: 18157
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus52 / 56401292
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma12 / 82823144
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor14 / 26384553
glioma8 / 10688374
head and neck tumor11 / 13630280
kidney tumor7 / 68959101
leukemia4 / 9584241
liver tumor8 / 9635983
lung tumor7 / 10312767
lymphoma7 / 7175597
non-neoplasia4 / 9725041
normal227 / 336030767
ovarian tumor9 / 76682117
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS28 / 125680222
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain110 / 110098999
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye13 / 21105461
heart4 / 8962644
intestine7 / 23447229
kidney13 / 21177761
larynx4 / 24145165
liver9 / 20774343
lung22 / 33697465
lymph3 / 4427067
lymph node12 / 91610130
mammary gland4 / 15327126
mouth4 / 6705259
muscle1 / 1077159
nerve1 / 1576863
ovary10 / 10205197
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta26 / 28082592
prostate4 / 18934521
salivary gland0 / 201550 
skin4 / 21057418
spleen3 / 5395255
stomach1 / 9661910
testis19 / 33044257
thymus4 / 8113149
thyroid5 / 47473105
tonsil3 / 16999176
trachea4 / 5241376
umbilical cord2 / 13680146
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203901_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.05
Adipocyte6.75
AdrenalCortex7
Adrenalgland5.7
Amygdala7.45
Appendix6.75
AtrioventricularNode5.2
BDCA4+_DentriticCells7.15
Bonemarrow6.55
BronchialEpithelialCells6.4
CD105+_Endothelial11.65
CD14+_Monocytes13.3
CD19+_BCells(neg._sel.)7.25
CD33+_Myeloid8.8
CD34+16.6
CD4+_Tcells8.1
CD56+_NKCells11.45
CD71+_EarlyErythroid7.1
CD8+_Tcells6.7
CardiacMyocytes9.3
Caudatenucleus6.05
Cerebellum6.05
CerebellumPeduncles7.95
CiliaryGanglion4.8
CingulateCortex7.1
Colorectaladenocarcinoma6.8
DorsalRootGanglion5.85
FetalThyroid6.85
Fetalbrain6.75
Fetalliver5.85
Fetallung5.85
GlobusPallidus5
Heart8.9
Hypothalamus6.9
Kidney5.35
Leukemia_chronicMyelogenousK-5625.95
Leukemia_promyelocytic-HL-606.1
Leukemialymphoblastic(MOLT-4)5.7
Liver10
Lung7.55
Lymphnode5.8
Lymphoma_burkitts(Daudi)8.55
Lymphoma_burkitts(Raji)9.8
MedullaOblongata6
OccipitalLobe6.15
OlfactoryBulb7.5
Ovary4.95
Pancreas5.45
PancreaticIslet7.35
ParietalLobe7.1
Pituitary7.8
Placenta8.05
Pons7.75
PrefrontalCortex8.75
Prostate8.95
Salivarygland8.25
SkeletalMuscle9.1
Skin5.6
SmoothMuscle7.6
Spinalcord7.05
SubthalamicNucleus6.45
SuperiorCervicalGanglion9.35
TemporalLobe6.3
Testis5.75
TestisGermCell5.7
TestisIntersitial5.75
TestisLeydigCell6.45
TestisSeminiferousTubule5.85
Thalamus7.15
Thymus5
Thyroid8.7
Tongue8.05
Tonsil6.65
Trachea5.85
TrigeminalGanglion7.25
Uterus5.5
UterusCorpus6.95
WholeBlood7.3
Wholebrain5.85
colon6.55
pineal_day9.04
pineal_night8.76
retina10.275
small_intestine6.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6806_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.52 ± 0.74
Basal Forebrain3.02 ± 0.64
Basal Part of Pons3.04 ± 0.32
Cerebellar Cortex3.26 ± 0.61
Cerebellar Nuclei3.24 ± 0.45
Claustrum3.47 ± 0.81
Epithalamus2.7 ± 0.65
Frontal Lobe3.2 ± 0.68
Globus Pallidus3.33 ± 0.6
Hypothalamus3.21 ± 0.52
Insula3.24 ± 0.61
Limbic Lobe3.25 ± 0.66
Mesencephalon3.31 ± 0.74
Myelencephalon3.3 ± 0.69
Occipital Lobe3.04 ± 0.62
Parietal Lobe3.2 ± 0.7
Pontine Tegmentum3.23 ± 0.51
Striatum3.46 ± 0.74
Subthalamus2.9 ± 0.72
Temporal Lobe3.25 ± 0.63
Thalamus3.44 ± 0.57
White Matter3.82 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Map3k7ip1PPons2.23
2.59
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007066 18 58 75 SENNCFLYGVFNGYDGNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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