AutismKB 2.0

Annotation Detail for MERTK


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Basic Information Top
Gene Symbol:MERTK ( MER,MGC133349,RP38,c-mer )
Gene Full Name: c-mer proto-oncogene tyrosine kinase
Band: 2q13
Quick LinksEntrez ID:10461; OMIM: 604705; Uniprot ID:MERTK_HUMAN; ENSEMBL ID: ENSG00000153208; HGNC ID: 7027
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus6 / 56401210
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal51 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine9 / 23447238
kidney2 / 2117779
larynx0 / 241450 
liver3 / 20774314
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206028_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte5
AdrenalCortex23.95
Adrenalgland14.3
Amygdala7.75
Appendix5.3
AtrioventricularNode4.65
BDCA4+_DentriticCells4.9
Bonemarrow5.1
BronchialEpithelialCells4.95
CD105+_Endothelial4.8
CD14+_Monocytes5.75
CD19+_BCells(neg._sel.)5.3
CD33+_Myeloid5.95
CD34+6.3
CD4+_Tcells5.3
CD56+_NKCells5.55
CD71+_EarlyErythroid4.7
CD8+_Tcells4.6
CardiacMyocytes6.8
Caudatenucleus5.3
Cerebellum4.05
CerebellumPeduncles5.8
CiliaryGanglion3.75
CingulateCortex5.25
Colorectaladenocarcinoma5.05
DorsalRootGanglion4
FetalThyroid5.6
Fetalbrain4.95
Fetalliver4.4
Fetallung6.1
GlobusPallidus3.8
Heart6.85
Hypothalamus5.75
Kidney4.6
Leukemia_chronicMyelogenousK-5624.65
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)4.05
Liver8.3
Lung5.65
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.45
Lymphoma_burkitts(Raji)7.05
MedullaOblongata4.7
OccipitalLobe4.9
OlfactoryBulb8.15
Ovary4.3
Pancreas4.1
PancreaticIslet7
ParietalLobe5.35
Pituitary8.8
Placenta7.05
Pons4.85
PrefrontalCortex18.05
Prostate6.6
Salivarygland4.2
SkeletalMuscle6.2
Skin4.05
SmoothMuscle5.65
Spinalcord5.6
SubthalamicNucleus4.7
SuperiorCervicalGanglion6.05
TemporalLobe4.7
Testis4.8
TestisGermCell34.6
TestisIntersitial5.25
TestisLeydigCell6
TestisSeminiferousTubule7.25
Thalamus5.85
Thymus3.9
Thyroid6.35
Tongue5.25
Tonsil5
Trachea4.3
TrigeminalGanglion7.8
Uterus5.1
UterusCorpus4.65
WholeBlood5.45
Wholebrain5.45
colon4.9
pineal_day6.08
pineal_night5.88
retina6.725
small_intestine4.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1103_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.53 ± 0.53
Basal Forebrain5.8 ± 0.4
Basal Part of Pons4.47 ± 0.35
Cerebellar Cortex4.56 ± 0.35
Cerebellar Nuclei5.17 ± 0.43
Claustrum5.68 ± 0.59
Epithalamus4.71 ± 0.49
Frontal Lobe4.85 ± 0.47
Globus Pallidus5.22 ± 0.32
Hypothalamus4.58 ± 0.86
Insula5.01 ± 0.43
Limbic Lobe5.02 ± 0.48
Mesencephalon5.26 ± 0.53
Myelencephalon5.14 ± 0.69
Occipital Lobe5.47 ± 0.68
Parietal Lobe5.12 ± 0.51
Pontine Tegmentum5.26 ± 0.46
Striatum6.18 ± 0.48
Subthalamus4.71 ± 0.39
Temporal Lobe5.09 ± 0.46
Thalamus5.15 ± 0.46
White Matter4.89 ± 0.52
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01369816 12 98 109 HTVGHIILSEHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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