AutismKB 2.0

Annotation Detail for COG5


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Basic Information Top
Gene Symbol:COG5 ( FLJ41732,FLJ44289,GOLTC1,GTC90 )
Gene Full Name: component of oligomeric golgi complex 5
Band: 7q22.3
Quick LinksEntrez ID:10466; OMIM: 606821; Uniprot ID:COG5_HUMAN; ENSEMBL ID: ENSG00000164597; HGNC ID: 14857
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus85 / 564012150
neonate1 / 3109732
infant0 / 236200 
juvenile6 / 55556107
adult138 / 193912171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor6 / 34366174
chondrosarcoma1 / 8282312
colorectal tumor8 / 11424670
esophageal tumor3 / 17290173
gastrointestinal tumor4 / 11936933
germ cell tumor24 / 26384590
glioma8 / 10688374
head and neck tumor11 / 13630280
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor3 / 9635931
lung tumor7 / 10312767
lymphoma6 / 7175583
non-neoplasia10 / 97250102
normal295 / 336030787
ovarian tumor3 / 7668239
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor6 / 12494948
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites2 / 4001549
bladder0 / 297570 
blood5 / 12347840
bone3 / 7165541
bone marrow2 / 4880140
brain108 / 110098998
cervix7 / 48171145
connective tissue12 / 14925580
ear3 / 16212185
embryonic tissue12 / 21572255
esophagus3 / 20209148
eye10 / 21105447
heart13 / 89626145
intestine19 / 23447281
kidney18 / 21177784
larynx1 / 2414541
liver8 / 20774338
lung23 / 33697468
lymph1 / 4427022
lymph node16 / 91610174
mammary gland17 / 153271110
mouth11 / 67052164
muscle4 / 10771537
nerve1 / 1576863
ovary4 / 10205139
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta8 / 28082528
prostate13 / 18934568
salivary gland1 / 2015549
skin13 / 21057461
spleen3 / 5395255
stomach4 / 9661941
testis41 / 330442124
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea20 / 52413381
umbilical cord0 / 136800 
uterus27 / 232878115
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203629_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.5
Adipocyte8.25
AdrenalCortex10.95
Adrenalgland8.35
Amygdala15.3
Appendix13.7
AtrioventricularNode10.75
BDCA4+_DentriticCells9.6
Bonemarrow11
BronchialEpithelialCells13.15
CD105+_Endothelial16.25
CD14+_Monocytes10.65
CD19+_BCells(neg._sel.)10.65
CD33+_Myeloid18.3
CD34+28.25
CD4+_Tcells9.5
CD56+_NKCells10.4
CD71+_EarlyErythroid8.7
CD8+_Tcells10.15
CardiacMyocytes15.35
Caudatenucleus8.2
Cerebellum7.5
CerebellumPeduncles11.5
CiliaryGanglion10.85
CingulateCortex9.65
Colorectaladenocarcinoma21.5
DorsalRootGanglion9.9
FetalThyroid11.2
Fetalbrain9.5
Fetalliver7.6
Fetallung7.25
GlobusPallidus7.2
Heart13.35
Hypothalamus9.4
Kidney8.05
Leukemia_chronicMyelogenousK-5628.85
Leukemia_promyelocytic-HL-607.9
Leukemialymphoblastic(MOLT-4)10.2
Liver12.5
Lung9.45
Lymphnode8.35
Lymphoma_burkitts(Daudi)13.8
Lymphoma_burkitts(Raji)13.9
MedullaOblongata7.6
OccipitalLobe8.35
OlfactoryBulb6.8
Ovary7
Pancreas7.6
PancreaticIslet10.15
ParietalLobe10.25
Pituitary11.35
Placenta8.85
Pons9
PrefrontalCortex10.85
Prostate17.25
Salivarygland11.35
SkeletalMuscle12.25
Skin9.4
SmoothMuscle10.9
Spinalcord12.2
SubthalamicNucleus8.7
SuperiorCervicalGanglion12.2
TemporalLobe8.4
Testis7.15
TestisGermCell7.35
TestisIntersitial7.65
TestisLeydigCell9
TestisSeminiferousTubule7.7
Thalamus9.5
Thymus6.9
Thyroid24.7
Tongue9.9
Tonsil9.05
Trachea12.05
TrigeminalGanglion10.55
Uterus19.45
UterusCorpus9.2
WholeBlood14.6
Wholebrain7
colon18.95
pineal_day22.74
pineal_night27.44
retina11.225
small_intestine22.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P134614
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.94 ± 0.32
Basal Forebrain6.99 ± 0.16
Basal Part of Pons6.76 ± 0.23
Cerebellar Cortex7.09 ± 0.3
Cerebellar Nuclei6.97 ± 0.28
Claustrum7.1 ± 0.74
Epithalamus7.12 ± 0.12
Frontal Lobe7.13 ± 0.25
Globus Pallidus6.78 ± 0.21
Hypothalamus7.3 ± 0.24
Insula7.22 ± 0.21
Limbic Lobe6.99 ± 0.34
Mesencephalon7.01 ± 0.39
Myelencephalon7 ± 0.33
Occipital Lobe6.87 ± 0.32
Parietal Lobe6.96 ± 0.29
Pontine Tegmentum7.05 ± 0.32
Striatum6.93 ± 0.27
Subthalamus7.09 ± 0.01
Temporal Lobe6.98 ± 0.28
Thalamus7.02 ± 0.2
White Matter7.14 ± 0.24
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
COG5_HUMAN_32 16 32 47 MEGGGGSVAVAGLGAR PRIDE
PAp00026595 17 337 353 LMDHIYAVCGQVQHLQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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