AutismKB 2.0

Annotation Detail for TADA3


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Basic Information Top
Gene Symbol:TADA3 ( ADA3,FLJ20221,FLJ21329,NGG1,TADA3L,hADA3 )
Gene Full Name: transcriptional adaptor 3
Band: 3p25.3
Quick LinksEntrez ID:10474; OMIM: 602945; Uniprot ID:TADA3_HUMAN; ENSEMBL ID: ENSG00000171148; HGNC ID: 19422
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile9 / 55556161
adult184 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor10 / 34366290
chondrosarcoma10 / 82823120
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor17 / 119369142
germ cell tumor30 / 263845113
glioma17 / 106883159
head and neck tumor5 / 13630236
kidney tumor15 / 68959217
leukemia8 / 9584283
liver tumor20 / 96359207
lung tumor30 / 103127290
lymphoma14 / 71755195
non-neoplasia6 / 9725061
normal190 / 336030756
ovarian tumor11 / 76682143
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer16 / 102680155
retinoblastoma13 / 46356280
skin tumor18 / 124949144
soft tissue/muscle tissue tumor24 / 125191191
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites5 / 40015124
bladder1 / 2975733
blood15 / 123478121
bone12 / 71655167
bone marrow4 / 4880181
brain69 / 110098962
cervix12 / 48171249
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye31 / 211054146
heart4 / 8962644
intestine25 / 234472106
kidney20 / 21177794
larynx1 / 2414541
liver20 / 20774396
lung48 / 336974142
lymph8 / 44270180
lymph node5 / 9161054
mammary gland10 / 15327165
mouth0 / 670520 
muscle14 / 107715129
nerve0 / 157680 
ovary19 / 102051186
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta42 / 280825149
prostate19 / 189345100
salivary gland1 / 2015549
skin19 / 21057490
spleen2 / 5395237
stomach2 / 9661920
testis23 / 33044269
thymus1 / 8113112
thyroid2 / 4747342
tonsil3 / 16999176
trachea1 / 5241319
umbilical cord0 / 136800 
uterus34 / 232878145
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215273_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts202.9
Adipocyte73.85
AdrenalCortex41.85
Adrenalgland87.55
Amygdala52.8
Appendix6.8
AtrioventricularNode12.55
BDCA4+_DentriticCells171.5
Bonemarrow39.3
BronchialEpithelialCells117.25
CD105+_Endothelial50.45
CD14+_Monocytes296.6
CD19+_BCells(neg._sel.)170
CD33+_Myeloid158.9
CD34+123.8
CD4+_Tcells108.95
CD56+_NKCells367.75
CD71+_EarlyErythroid38.05
CD8+_Tcells45.55
CardiacMyocytes63.05
Caudatenucleus50.5
Cerebellum20.65
CerebellumPeduncles30.6
CiliaryGanglion11.45
CingulateCortex57.75
Colorectaladenocarcinoma99.05
DorsalRootGanglion11.75
FetalThyroid32.45
Fetalbrain67.75
Fetalliver24.9
Fetallung38.55
GlobusPallidus38.4
Heart243.45
Hypothalamus72.35
Kidney21.55
Leukemia_chronicMyelogenousK-56257.2
Leukemia_promyelocytic-HL-6027.45
Leukemialymphoblastic(MOLT-4)37.75
Liver56.25
Lung161.7
Lymphnode31.4
Lymphoma_burkitts(Daudi)51.45
Lymphoma_burkitts(Raji)47
MedullaOblongata26.05
OccipitalLobe67.6
OlfactoryBulb42.8
Ovary11.9
Pancreas17.65
PancreaticIslet49.65
ParietalLobe58.3
Pituitary25.8
Placenta56.75
Pons18.25
PrefrontalCortex104.85
Prostate260.35
Salivarygland10.65
SkeletalMuscle13.85
Skin9.45
SmoothMuscle90.5
Spinalcord52.75
SubthalamicNucleus53.7
SuperiorCervicalGanglion10
TemporalLobe42
Testis130.3
TestisGermCell139.8
TestisIntersitial99.35
TestisLeydigCell43.55
TestisSeminiferousTubule95.3
Thalamus87.2
Thymus80.55
Thyroid143.15
Tongue23.3
Tonsil42.3
Trachea14.3
TrigeminalGanglion15.8
Uterus64.35
UterusCorpus11.05
WholeBlood211.55
Wholebrain189.65
colon15.1
pineal_day154.46
pineal_night110.2
retina63.05
small_intestine14.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P109821
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.12 ± 0.18
Basal Forebrain11.15 ± 0.15
Basal Part of Pons11.04 ± 0.27
Cerebellar Cortex10.86 ± 0.13
Cerebellar Nuclei11.06 ± 0.16
Claustrum10.79 ± 0.28
Epithalamus10.98 ± 0.3
Frontal Lobe11.24 ± 0.3
Globus Pallidus11.6 ± 0.21
Hypothalamus11 ± 0.27
Insula11.26 ± 0.19
Limbic Lobe11.16 ± 0.35
Mesencephalon11.24 ± 0.36
Myelencephalon11.2 ± 0.32
Occipital Lobe11.07 ± 0.26
Parietal Lobe11.21 ± 0.3
Pontine Tegmentum11.23 ± 0.36
Striatum11.5 ± 0.25
Subthalamus11.33 ± 0.33
Temporal Lobe11.17 ± 0.25
Thalamus11.3 ± 0.25
White Matter10.32 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tada3lCBCerebellum33.96
59.67
Tada3lCTXCerebral cortex99.11
87.55
Tada3lHIPHippocampal region55.38
96.64
Tada3lHPFHippocampal formation63.29
84.87
Tada3lHYHypothalamus46.85
39.13
Tada3lLSXLateral septal complex55.51
40.29
Tada3lMBMidbrain45.64
42.22
Tada3lMYMedulla54.29
63.5
Tada3lOLFOlfactory bulb87.54
88.57
Tada3lPPons42.44
46.94
Tada3lPALPallidum42.06
38.53
Tada3lRHPRetrohippocampal region75.77
70.45
Tada3lsAMYStriatum-like amygdalar nuclei35.4
27.97
Tada3lSTRStriatum51.83
39.42
Tada3lSTRdStriatum dorsal region47.68
36.11
Tada3lSTRvStriatum ventral region76.6
57.1
Tada3lTHThalamus77.64
70.57
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004572 21 243 263 KSEAQHEQPEDGCPFGALTQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018