AutismKB 2.0

Annotation Detail for SLC25A17


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Basic Information Top
Gene Symbol:SLC25A17 ( PMP34 )
Gene Full Name: solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
Band: 22q13.2
Quick LinksEntrez ID:10478; OMIM: 606795; Uniprot ID:PM34_HUMAN; ENSEMBL ID: ENSG00000100372; HGNC ID: 10987
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst6 / 6231996
fetus17 / 56401230
neonate1 / 3109732
infant5 / 23620211
juvenile3 / 5555653
adult78 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor15 / 26384556
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia8 / 9584283
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal156 / 336030746
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer7 / 10268068
retinoblastoma2 / 4635643
skin tumor17 / 124949136
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites3 / 4001574
bladder1 / 2975733
blood7 / 12347856
bone3 / 7165541
bone marrow4 / 4880181
brain69 / 110098962
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye5 / 21105423
heart5 / 8962655
intestine8 / 23447234
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary5 / 10205148
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta13 / 28082546
prostate12 / 18934563
salivary gland0 / 201550 
skin20 / 21057494
spleen4 / 5395274
stomach4 / 9661941
testis17 / 33044251
thymus3 / 8113136
thyroid3 / 4747363
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214210_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.9
Adipocyte6.25
AdrenalCortex6.75
Adrenalgland5.35
Amygdala6.05
Appendix6.15
AtrioventricularNode4.8
BDCA4+_DentriticCells6.4
Bonemarrow5.9
BronchialEpithelialCells5.7
CD105+_Endothelial5.9
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid7.2
CD34+10.7
CD4+_Tcells6.1
CD56+_NKCells6.65
CD71+_EarlyErythroid5.55
CD8+_Tcells5.85
CardiacMyocytes8.25
Caudatenucleus5.25
Cerebellum4.8
CerebellumPeduncles7.25
CiliaryGanglion4.2
CingulateCortex6.1
Colorectaladenocarcinoma5.8
DorsalRootGanglion4.8
FetalThyroid5.75
Fetalbrain5.65
Fetalliver5.2
Fetallung4.75
GlobusPallidus4.35
Heart8.2
Hypothalamus6.55
Kidney5
Leukemia_chronicMyelogenousK-5625.25
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)5.55
Liver8.7
Lung6.2
Lymphnode4.9
Lymphoma_burkitts(Daudi)7.5
Lymphoma_burkitts(Raji)8.05
MedullaOblongata5.3
OccipitalLobe5.15
OlfactoryBulb4.5
Ovary4.15
Pancreas4.7
PancreaticIslet6.15
ParietalLobe6.45
Pituitary6.85
Placenta5.9
Pons5.75
PrefrontalCortex7
Prostate6.7
Salivarygland4.75
SkeletalMuscle7.75
Skin4.85
SmoothMuscle6.5
Spinalcord7.1
SubthalamicNucleus5.5
SuperiorCervicalGanglion7.2
TemporalLobe6
Testis5.6
TestisGermCell5.1
TestisIntersitial5
TestisLeydigCell6.55
TestisSeminiferousTubule5.05
Thalamus6.4
Thymus4.5
Thyroid7.05
Tongue6.1
Tonsil5.75
Trachea5.6
TrigeminalGanglion6.8
Uterus4.6
UterusCorpus5.7
WholeBlood6.35
Wholebrain4.6
colon5.75
pineal_day7.26
pineal_night7
retina7.775
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1841_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.45 ± 0.59
Basal Forebrain4.39 ± 0.42
Basal Part of Pons4.53 ± 0.54
Cerebellar Cortex4.79 ± 0.24
Cerebellar Nuclei4.3 ± 0.5
Claustrum3.93 ± 0.64
Epithalamus5.16 ± 0.42
Frontal Lobe4.51 ± 0.42
Globus Pallidus4.26 ± 0.64
Hypothalamus4.94 ± 0.29
Insula4.4 ± 0.38
Limbic Lobe4.31 ± 0.44
Mesencephalon4.42 ± 0.41
Myelencephalon4.47 ± 0.52
Occipital Lobe4.5 ± 0.36
Parietal Lobe4.51 ± 0.48
Pontine Tegmentum4.45 ± 0.51
Striatum4.25 ± 0.46
Subthalamus3.99 ± 0.51
Temporal Lobe4.39 ± 0.46
Thalamus4.51 ± 0.37
White Matter5.18 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc25a17CBCerebellum32.83
45.52
Slc25a17CTXCerebral cortex59.12
44.37
Slc25a17HIPHippocampal region40.83
52.22
Slc25a17HPFHippocampal formation40.56
43.94
Slc25a17HYHypothalamus49.77
40.13
Slc25a17LSXLateral septal complex55.71
43.8
Slc25a17MBMidbrain51.02
47.21
Slc25a17MYMedulla58.23
67.05
Slc25a17OLFOlfactory bulb61.14
52.71
Slc25a17PPons51.95
57.42
Slc25a17PALPallidum45.57
41.61
Slc25a17RHPRetrohippocampal region40.7
32.37
Slc25a17sAMYStriatum-like amygdalar nuclei33.25
26.37
Slc25a17STRStriatum39.98
29.03
Slc25a17STRdStriatum dorsal region35.42
25.2
Slc25a17STRvStriatum ventral region49.23
33.32
Slc25a17THThalamus58.37
52.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00041919 9 249 257 NILYLLHQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018