Annotation Detail for SLC9A6
Basic Information Top
| Gene Symbol: | SLC9A6 ( KIAA0267,MRSA,NHE6 ) |
|---|---|
| Gene Full Name: | solute carrier family 9 (sodium/hydrogen exchanger), member 6 |
| Band: | Xq26.3 |
| Quick Links | Entrez ID:10479; OMIM: 300231; Uniprot ID:SL9A6_HUMAN; ENSEMBL ID: ENSG00000198689; HGNC ID: 11079 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.62185
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 32 / 564012 | 56 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 42 / 1939121 | 21 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 168 / 3360307 | 49 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 2 / 123478 | 16 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 94 / 1100989 | 85 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 11 / 211054 | 52 | |
| heart | 3 / 89626 | 33 | |
| intestine | 5 / 234472 | 21 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 11 / 336974 | 32 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 4 / 20539 | 194 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 5 / 210574 | 23 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 9 / 330442 | 27 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203909_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 57 | |
| Adipocyte | 7.7 | |
| AdrenalCortex | 7.65 | |
| Adrenalgland | 8.95 | |
| Amygdala | 383.05 |  |
| Appendix | 7.65 | |
| AtrioventricularNode | 5.5 | |
| BDCA4+_DentriticCells | 100.4 | |
| Bonemarrow | 6.8 | |
| BronchialEpithelialCells | 14.35 | |
| CD105+_Endothelial | 17.2 | |
| CD14+_Monocytes | 64.15 | |
| CD19+_BCells(neg._sel.) | 36.05 | |
| CD33+_Myeloid | 100 | |
| CD34+ | 89.5 | |
| CD4+_Tcells | 64.9 | |
| CD56+_NKCells | 105.05 | |
| CD71+_EarlyErythroid | 7.75 | |
| CD8+_Tcells | 73.25 | |
| CardiacMyocytes | 8.25 | |
| Caudatenucleus | 138.5 | |
| Cerebellum | 35.8 | |
| CerebellumPeduncles | 93.15 | |
| CiliaryGanglion | 4.95 | |
| CingulateCortex | 220.1 | |
| Colorectaladenocarcinoma | 11.3 | |
| DorsalRootGanglion | 6.45 | |
| FetalThyroid | 9.4 | |
| Fetalbrain | 427.9 | |
| Fetalliver | 5.65 | |
| Fetallung | 8.95 | |
| GlobusPallidus | 97.35 | |
| Heart | 8.1 | |
| Hypothalamus | 585.05 | |
| Kidney | 6.5 | |
| Leukemia_chronicMyelogenousK-562 | 6.35 | |
| Leukemia_promyelocytic-HL-60 | 6.95 | |
| Leukemialymphoblastic(MOLT-4) | 15.5 | |
| Liver | 8.5 | |
| Lung | 8.85 | |
| Lymphnode | 8.4 | |
| Lymphoma_burkitts(Daudi) | 9.8 | |
| Lymphoma_burkitts(Raji) | 9.6 | |
| MedullaOblongata | 159.5 | |
| OccipitalLobe | 307 | |
| OlfactoryBulb | 19.4 | |
| Ovary | 4.9 | |
| Pancreas | 7.85 | |
| PancreaticIslet | 9.6 | |
| ParietalLobe | 179.4 | |
| Pituitary | 115 | |
| Placenta | 8.1 | |
| Pons | 71.6 | |
| PrefrontalCortex | 573.1 | |
| Prostate | 8.25 | |
| Salivarygland | 6 | |
| SkeletalMuscle | 8.5 | |
| Skin | 5.5 | |
| SmoothMuscle | 25.55 | |
| Spinalcord | 131.35 | |
| SubthalamicNucleus | 216.55 | |
| SuperiorCervicalGanglion | 8.55 | |
| TemporalLobe | 158.75 | |
| Testis | 6.9 | |
| TestisGermCell | 15.05 | |
| TestisIntersitial | 6.3 | |
| TestisLeydigCell | 7.5 | |
| TestisSeminiferousTubule | 7.5 | |
| Thalamus | 236.45 | |
| Thymus | 9.25 | |
| Thyroid | 18.95 | |
| Tongue | 6.5 | |
| Tonsil | 7.8 | |
| Trachea | 6.4 | |
| TrigeminalGanglion | 6.85 | |
| Uterus | 11.35 | |
| UterusCorpus | 6.55 | |
| WholeBlood | 39.65 | |
| Wholebrain | 264.95 | |
| colon | 10 | |
| pineal_day | 197.86 | |
| pineal_night | 209.28 | |
| retina | 62.9 | |
| small_intestine | 18.9 | |
- Probe name: A_24_P410562
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.91 ± 0.64 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.73 ± 0.6 | |
| Basal Part of Pons | 3.59 ± 0.51 | |
| Cerebellar Cortex | 4.11 ± 0.42 | |
| Cerebellar Nuclei | 3.84 ± 0.43 | |
| Claustrum | 4.02 ± 0.78 | |
| Epithalamus | 3.45 ± 0.65 | |
| Frontal Lobe | 3.99 ± 0.56 | |
| Globus Pallidus | 3.25 ± 0.48 | |
| Hypothalamus | 4.54 ± 0.29 | |
| Insula | 4.11 ± 0.54 | |
| Limbic Lobe | 4.09 ± 0.47 | |
| Mesencephalon | 4.02 ± 0.62 | |
| Myelencephalon | 3.91 ± 0.59 | |
| Occipital Lobe | 3.72 ± 0.78 | |
| Parietal Lobe | 3.91 ± 0.6 | |
| Pontine Tegmentum | 3.91 ± 0.58 | |
| Striatum | 3.32 ± 0.63 | |
| Subthalamus | 3.96 ± 0.11 | |
| Temporal Lobe | 4.06 ± 0.47 | |
| Thalamus | 3.67 ± 0.65 | |
| White Matter | 3.26 ± 0.87 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Slc9a6 | CB | Cerebellum | 34.33 | |
| 48.05 | | |||
| Slc9a6 | CTX | Cerebral cortex | 96.45 | |
| 76.94 | | |||
| Slc9a6 | HIP | Hippocampal region | 60.96 | |
| 93.38 | | |||
| Slc9a6 | HPF | Hippocampal formation | 71.18 | |
| 77.05 | | |||
| Slc9a6 | HY | Hypothalamus | 92.43 | |
| 75.03 | | |||
| Slc9a6 | LSX | Lateral septal complex | 29.61 | |
| 16.53 | | |||
| Slc9a6 | MB | Midbrain | 80.41 | |
| 70.05 | | |||
| Slc9a6 | MY | Medulla | 72.81 | |
| 76.67 | | |||
| Slc9a6 | OLF | Olfactory bulb | 75.55 | |
| 57.18 | | |||
| Slc9a6 | P | Pons | 76.96 | |
| 74.42 | | |||
| Slc9a6 | PAL | Pallidum | 75.07 | |
| 64 | | |||
| Slc9a6 | RHP | Retrohippocampal region | 82.96 | |
| 60.47 | | |||
| Slc9a6 | sAMY | Striatum-like amygdalar nuclei | 90.62 | |
| 72.83 | | |||
| Slc9a6 | STR | Striatum | 60.63 | |
| 39.39 | | |||
| Slc9a6 | STRd | Striatum dorsal region | 54.33 | |
| 34.55 | | |||
| Slc9a6 | STRv | Striatum ventral region | 69.65 | |
| 42.24 | | |||
| Slc9a6 | TH | Thalamus | 41.98 | |
| 32.44 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00002765 | 19 | 157 | 175 | GEISSHELNNVQDNEMLRK | Peptide Atlas |
| SL9A6_HUMAN_647 | 19 | 647 | 665 | LVLPMDDSEPPLNLLDNTR | PRIDE |