AutismKB 2.0

Annotation Detail for CREB3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CREB3 ( LUMAN,LZIP,MGC15333,MGC19782 )
Gene Full Name: cAMP responsive element binding protein 3
Band: 9p13.3
Quick LinksEntrez ID:10488; OMIM: 606443; Uniprot ID:CREB3_HUMAN; ENSEMBL ID: ENSG00000107175; HGNC ID: 2347
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst3 / 6231948
fetus14 / 56401224
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult99 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma10 / 82823120
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor5 / 26384518
glioma13 / 106883121
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal137 / 336030740
ovarian tumor7 / 7668291
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor8 / 12494964
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow1 / 4880120
brain61 / 110098955
cervix7 / 48171145
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye9 / 21105442
heart1 / 8962611
intestine13 / 23447255
kidney9 / 21177742
larynx0 / 241450 
liver7 / 20774333
lung27 / 33697480
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary11 / 102051107
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate7 / 18934536
salivary gland4 / 20155198
skin19 / 21057490
spleen0 / 539520 
stomach1 / 9661910
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209432_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts30.55
Adipocyte24
AdrenalCortex19.95
Adrenalgland51.45
Amygdala21.5
Appendix16.1
AtrioventricularNode10.1
BDCA4+_DentriticCells19.75
Bonemarrow18.35
BronchialEpithelialCells53.75
CD105+_Endothelial9.35
CD14+_Monocytes18.7
CD19+_BCells(neg._sel.)15.35
CD33+_Myeloid15.6
CD34+19.25
CD4+_Tcells17.55
CD56+_NKCells24.1
CD71+_EarlyErythroid14.7
CD8+_Tcells13.05
CardiacMyocytes38.25
Caudatenucleus29.65
Cerebellum52.5
CerebellumPeduncles61.95
CiliaryGanglion5.6
CingulateCortex26.4
Colorectaladenocarcinoma41.8
DorsalRootGanglion5.25
FetalThyroid31.6
Fetalbrain19.1
Fetalliver13.6
Fetallung18.85
GlobusPallidus12.35
Heart43.05
Hypothalamus36.5
Kidney20.6
Leukemia_chronicMyelogenousK-56214.75
Leukemia_promyelocytic-HL-6013.9
Leukemialymphoblastic(MOLT-4)18.25
Liver64.35
Lung45.25
Lymphnode14.4
Lymphoma_burkitts(Daudi)21.3
Lymphoma_burkitts(Raji)21.9
MedullaOblongata27.5
OccipitalLobe20.35
OlfactoryBulb12.75
Ovary10.3
Pancreas13.3
PancreaticIslet31.15
ParietalLobe24.1
Pituitary49.7
Placenta36.65
Pons18.7
PrefrontalCortex33.65
Prostate112.5
Salivarygland12.5
SkeletalMuscle27.8
Skin4.45
SmoothMuscle83.9
Spinalcord24.45
SubthalamicNucleus17.4
SuperiorCervicalGanglion19.25
TemporalLobe27
Testis47.2
TestisGermCell26.75
TestisIntersitial27.55
TestisLeydigCell22.55
TestisSeminiferousTubule18
Thalamus28.05
Thymus19.3
Thyroid44.25
Tongue15.05
Tonsil15.3
Trachea17.65
TrigeminalGanglion15.1
Uterus17
UterusCorpus15.95
WholeBlood24.2
Wholebrain97.55
colon17.45
pineal_day24.94
pineal_night21.84
retina24.55
small_intestine15.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6441_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.91 ± 0.29
Basal Forebrain7.02 ± 0.27
Basal Part of Pons6.59 ± 0.22
Cerebellar Cortex6.68 ± 0.3
Cerebellar Nuclei6.74 ± 0.25
Claustrum7.01 ± 0.41
Epithalamus6.94 ± 0.2
Frontal Lobe6.74 ± 0.31
Globus Pallidus6.91 ± 0.28
Hypothalamus7.05 ± 0.27
Insula6.78 ± 0.29
Limbic Lobe6.73 ± 0.25
Mesencephalon6.87 ± 0.32
Myelencephalon6.78 ± 0.27
Occipital Lobe6.55 ± 0.25
Parietal Lobe6.77 ± 0.26
Pontine Tegmentum6.77 ± 0.27
Striatum6.86 ± 0.23
Subthalamus6.66 ± 0.36
Temporal Lobe6.81 ± 0.28
Thalamus6.7 ± 0.21
White Matter7.06 ± 0.27
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved