AutismKB 2.0

Annotation Detail for LRRC41


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LRRC41 ( MGC126571,MGC126573,MUF1,RP4-636H5.2 )
Gene Full Name: leucine rich repeat containing 41
Band: 1p34.1-p33
Quick LinksEntrez ID:10489; OMIM: NA; Uniprot ID:LRC41_HUMAN; ENSEMBL ID: ENSG00000132128; HGNC ID: 16917
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst5 / 6231980
fetus72 / 564012127
neonate17 / 31097546
infant0 / 236200 
juvenile3 / 5555653
adult285 / 1939121146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor13 / 94178138
cervical tumor3 / 3436687
chondrosarcoma19 / 82823229
colorectal tumor4 / 11424635
esophageal tumor4 / 17290231
gastrointestinal tumor15 / 119369125
germ cell tumor111 / 263845420
glioma8 / 10688374
head and neck tumor23 / 136302168
kidney tumor6 / 6895987
leukemia12 / 95842125
liver tumor3 / 9635931
lung tumor5 / 10312748
lymphoma7 / 7175597
non-neoplasia10 / 97250102
normal422 / 3360307125
ovarian tumor14 / 76682182
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer12 / 102680116
retinoblastoma7 / 46356151
skin tumor15 / 124949120
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites2 / 4001549
bladder4 / 29757134
blood12 / 12347897
bone4 / 7165555
bone marrow6 / 48801122
brain162 / 1100989147
cervix7 / 48171145
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue27 / 215722125
esophagus4 / 20209197
eye18 / 21105485
heart11 / 89626122
intestine20 / 23447285
kidney41 / 211777193
larynx1 / 2414541
liver7 / 20774333
lung39 / 336974115
lymph7 / 44270158
lymph node6 / 9161065
mammary gland17 / 153271110
mouth15 / 67052223
muscle17 / 107715157
nerve1 / 1576863
ovary17 / 102051166
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta45 / 280825160
prostate31 / 189345163
salivary gland0 / 201550 
skin37 / 210574175
spleen2 / 5395237
stomach9 / 9661993
testis96 / 330442290
thymus38 / 81131468
thyroid8 / 47473168
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord2 / 13680146
uterus24 / 232878103
vascular13 / 51780251
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201932_at
Cell line Expression level Expression bar
721_B_lymphoblasts234.5
Adipocyte36.85
AdrenalCortex35.2
Adrenalgland50.4
Amygdala35.9
Appendix16.6
AtrioventricularNode24.1
BDCA4+_DentriticCells100.15
Bonemarrow33.2
BronchialEpithelialCells147.3
CD105+_Endothelial93.25
CD14+_Monocytes45.8
CD19+_BCells(neg._sel.)61.95
CD33+_Myeloid53.45
CD34+97.65
CD4+_Tcells46.2
CD56+_NKCells83.9
CD71+_EarlyErythroid72.05
CD8+_Tcells65.6
CardiacMyocytes101.7
Caudatenucleus33.15
Cerebellum47.95
CerebellumPeduncles37.9
CiliaryGanglion22.25
CingulateCortex35.85
Colorectaladenocarcinoma36.7
DorsalRootGanglion24.35
FetalThyroid47.9
Fetalbrain43.15
Fetalliver33.7
Fetallung60.4
GlobusPallidus23.2
Heart122.2
Hypothalamus48.65
Kidney33.2
Leukemia_chronicMyelogenousK-56253.05
Leukemia_promyelocytic-HL-6026.1
Leukemialymphoblastic(MOLT-4)57.85
Liver55.15
Lung98.7
Lymphnode26.15
Lymphoma_burkitts(Daudi)42.35
Lymphoma_burkitts(Raji)47.35
MedullaOblongata27.6
OccipitalLobe34
OlfactoryBulb35
Ovary22.05
Pancreas26.15
PancreaticIslet48.45
ParietalLobe38.85
Pituitary52.7
Placenta206.8
Pons32.65
PrefrontalCortex70.95
Prostate137.25
Salivarygland26.05
SkeletalMuscle26.35
Skin26.05
SmoothMuscle141.9
Spinalcord35.65
SubthalamicNucleus36.75
SuperiorCervicalGanglion19.1
TemporalLobe30.35
Testis69.2
TestisGermCell49.15
TestisIntersitial29.65
TestisLeydigCell34.6
TestisSeminiferousTubule42.55
Thalamus37.25
Thymus58.35
Thyroid166
Tongue35.6
Tonsil34.4
Trachea30.9
TrigeminalGanglion33.2
Uterus41.8
UterusCorpus25.5
WholeBlood32.8
Wholebrain52
colon38.85
pineal_day122.34
pineal_night95.4
retina121.975
small_intestine41.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2039_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.83 ± 0.78
Basal Forebrain8.49 ± 0.35
Basal Part of Pons8.68 ± 0.55
Cerebellar Cortex8.18 ± 0.38
Cerebellar Nuclei8.57 ± 0.38
Claustrum8.98 ± 0.65
Epithalamus7.98 ± 0.61
Frontal Lobe8.46 ± 0.5
Globus Pallidus8.92 ± 0.47
Hypothalamus8.39 ± 0.35
Insula8.31 ± 0.42
Limbic Lobe8.64 ± 0.53
Mesencephalon8.57 ± 0.47
Myelencephalon8.54 ± 0.52
Occipital Lobe8.56 ± 0.54
Parietal Lobe8.47 ± 0.49
Pontine Tegmentum8.31 ± 0.42
Striatum8.49 ± 0.57
Subthalamus8.51 ± 0.43
Temporal Lobe8.39 ± 0.53
Thalamus8.49 ± 0.43
White Matter8.29 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrc41CBCerebellum21.47
26.73
Lrrc41CTXCerebral cortex48.44
35.75
Lrrc41HIPHippocampal region34
37.11
Lrrc41HPFHippocampal formation33.95
32.91
Lrrc41HYHypothalamus10.4
8.39
Lrrc41LSXLateral septal complex20.89
14.31
Lrrc41MBMidbrain13.22
12.47
Lrrc41MYMedulla13.98
16.04
Lrrc41OLFOlfactory bulb44.18
36.5
Lrrc41PPons12.65
15.69
Lrrc41PALPallidum14.15
12.78
Lrrc41RHPRetrohippocampal region34.29
27.14
Lrrc41sAMYStriatum-like amygdalar nuclei27.47
20.07
Lrrc41STRStriatum12.9
9.41
Lrrc41STRdStriatum dorsal region10.14
7.66
Lrrc41STRvStriatum ventral region13.41
8.92
Lrrc41THThalamus14.67
12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00131854 19 357 375 SPSAPAATSSASSSTSSYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved