AutismKB 2.0

Annotation Detail for STK25


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Basic Information Top
Gene Symbol:STK25 ( DKFZp686J1430,SOK1,YSK1 )
Gene Full Name: serine/threonine kinase 25
Band: 2q37.3
Quick LinksEntrez ID:10494; OMIM: 602255; Uniprot ID:STK25_HUMAN; ENSEMBL ID: ENSG00000115694; HGNC ID: 11404
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst10 / 62319160
fetus53 / 56401293
neonate1 / 3109732
infant3 / 23620127
juvenile8 / 55556143
adult249 / 1939121128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor2 / 3436658
chondrosarcoma12 / 82823144
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor16 / 119369134
germ cell tumor58 / 263845219
glioma29 / 106883271
head and neck tumor32 / 136302234
kidney tumor14 / 68959203
leukemia39 / 95842406
liver tumor31 / 96359321
lung tumor29 / 103127281
lymphoma3 / 7175541
non-neoplasia9 / 9725092
normal380 / 3360307113
ovarian tumor10 / 76682130
pancreatic tumor35 / 104616334
primitive neuroectodermal tumor of the CNS42 / 125680334
prostate cancer31 / 102680301
retinoblastoma20 / 46356431
skin tumor12 / 12494996
soft tissue/muscle tissue tumor67 / 125191535
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder3 / 29757100
blood9 / 12347872
bone12 / 71655167
bone marrow19 / 48801389
brain151 / 1100989137
cervix2 / 4817141
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue38 / 215722176
esophagus0 / 202090 
eye55 / 211054260
heart1 / 8962611
intestine19 / 23447281
kidney27 / 211777127
larynx2 / 2414582
liver38 / 207743182
lung52 / 336974154
lymph3 / 4427067
lymph node39 / 91610425
mammary gland12 / 15327178
mouth3 / 6705244
muscle34 / 107715315
nerve5 / 15768317
ovary26 / 102051254
pancreas46 / 214812214
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta22 / 28082578
prostate39 / 189345205
salivary gland15 / 20155744
skin19 / 21057490
spleen13 / 53952240
stomach15 / 96619155
testis65 / 330442196
thymus17 / 81131209
thyroid13 / 47473273
tonsil14 / 16999823
trachea4 / 5241376
umbilical cord1 / 1368073
uterus66 / 232878283
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201314_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.75
Adipocyte3.9
AdrenalCortex4.25
Adrenalgland3.05
Amygdala27.25
Appendix3.65
AtrioventricularNode2.7
BDCA4+_DentriticCells8.9
Bonemarrow5.25
BronchialEpithelialCells6.65
CD105+_Endothelial21.4
CD14+_Monocytes7.4
CD19+_BCells(neg._sel.)11.2
CD33+_Myeloid7.05
CD34+25.5
CD4+_Tcells11.7
CD56+_NKCells13.95
CD71+_EarlyErythroid16.65
CD8+_Tcells14
CardiacMyocytes7.2
Caudatenucleus4.5
Cerebellum6.1
CerebellumPeduncles5.95
CiliaryGanglion2.15
CingulateCortex5.55
Colorectaladenocarcinoma11.65
DorsalRootGanglion3.1
FetalThyroid5.45
Fetalbrain9.8
Fetalliver4.25
Fetallung6
GlobusPallidus3.65
Heart18.85
Hypothalamus11.5
Kidney3.4
Leukemia_chronicMyelogenousK-5624.5
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)15.6
Liver7.3
Lung23.35
Lymphnode4.95
Lymphoma_burkitts(Daudi)5.15
Lymphoma_burkitts(Raji)13.35
MedullaOblongata5.1
OccipitalLobe4.85
OlfactoryBulb4.05
Ovary2.65
Pancreas4.1
PancreaticIslet4.95
ParietalLobe5.4
Pituitary5.6
Placenta6.55
Pons4.9
PrefrontalCortex23.25
Prostate17.55
Salivarygland3.45
SkeletalMuscle6.3
Skin2.3
SmoothMuscle7.55
Spinalcord5.55
SubthalamicNucleus4.7
SuperiorCervicalGanglion4.9
TemporalLobe5.6
Testis13.6
TestisGermCell6.45
TestisIntersitial4.45
TestisLeydigCell5.1
TestisSeminiferousTubule4.75
Thalamus5.25
Thymus7.2
Thyroid39.65
Tongue5
Tonsil4.35
Trachea3.15
TrigeminalGanglion3.75
Uterus12.25
UterusCorpus4.55
WholeBlood6.6
Wholebrain32.05
colon4.9
pineal_day12.56
pineal_night13.18
retina7.375
small_intestine4.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P276983
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.39 ± 0.51
Basal Forebrain6.7 ± 0.55
Basal Part of Pons6.7 ± 0.5
Cerebellar Cortex6.7 ± 0.5
Cerebellar Nuclei6.22 ± 0.44
Claustrum6.37 ± 0.71
Epithalamus6.44 ± 0.39
Frontal Lobe6.75 ± 0.45
Globus Pallidus5.79 ± 0.38
Hypothalamus6.87 ± 0.48
Insula6.99 ± 0.29
Limbic Lobe6.57 ± 0.58
Mesencephalon6.42 ± 0.53
Myelencephalon6.54 ± 0.55
Occipital Lobe5.94 ± 0.62
Parietal Lobe6.46 ± 0.49
Pontine Tegmentum6.49 ± 0.58
Striatum6.2 ± 0.49
Subthalamus6.6 ± 0.34
Temporal Lobe6.83 ± 0.44
Thalamus6.45 ± 0.44
White Matter6.05 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Stk25CBCerebellum96.09
100
Stk25CTXCerebral cortex100
100
Stk25HIPHippocampal region100
100
Stk25HPFHippocampal formation100
100
Stk25HYHypothalamus100
100
Stk25LSXLateral septal complex100
100
Stk25MBMidbrain100
100
Stk25MYMedulla100
100
Stk25OLFOlfactory bulb100
100
Stk25PPons100
100
Stk25PALPallidum100
100
Stk25RHPRetrohippocampal region100
100
Stk25sAMYStriatum-like amygdalar nuclei100
100
Stk25STRStriatum100
100
Stk25STRdStriatum dorsal region100
100
Stk25STRvStriatum ventral region100
100
Stk25THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072380 16 156 171 LADFGVAGQLTDTQIK Peptide Atlas
STK25_HUMAN_1 5 1 5 MAHLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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