AutismKB 2.0

Annotation Detail for CARM1


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Basic Information Top
Gene Symbol:CARM1 ( PRMT4 )
Gene Full Name: coactivator-associated arginine methyltransferase 1
Band: 19p13.2
Quick LinksEntrez ID:10498; OMIM: 603934; Uniprot ID:CARM1_HUMAN; ENSEMBL ID: ENSG00000142453; HGNC ID: 23393
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult132 / 193912168
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor7 / 34366203
chondrosarcoma16 / 82823193
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor17 / 119369142
germ cell tumor16 / 26384560
glioma23 / 106883215
head and neck tumor8 / 13630258
kidney tumor6 / 6895987
leukemia8 / 9584283
liver tumor6 / 9635962
lung tumor9 / 10312787
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal162 / 336030748
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer9 / 10268087
retinoblastoma8 / 46356172
skin tumor12 / 12494996
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites10 / 40015249
bladder1 / 2975733
blood8 / 12347864
bone9 / 71655125
bone marrow1 / 4880120
brain44 / 110098939
cervix7 / 48171145
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus0 / 202090 
eye23 / 211054108
heart2 / 8962622
intestine18 / 23447276
kidney11 / 21177751
larynx3 / 24145124
liver6 / 20774328
lung29 / 33697486
lymph4 / 4427090
lymph node4 / 9161043
mammary gland14 / 15327191
mouth1 / 6705214
muscle3 / 10771527
nerve2 / 15768126
ovary9 / 10205188
pancreas9 / 21481241
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate14 / 18934573
salivary gland3 / 20155148
skin15 / 21057471
spleen0 / 539520 
stomach7 / 9661972
testis12 / 33044236
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus22 / 23287894
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212512_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts433.65
Adipocyte68
AdrenalCortex40.85
Adrenalgland28.65
Amygdala59.75
Appendix26
AtrioventricularNode20.25
BDCA4+_DentriticCells40.15
Bonemarrow43.65
BronchialEpithelialCells104.75
CD105+_Endothelial120.9
CD14+_Monocytes59.65
CD19+_BCells(neg._sel.)49.95
CD33+_Myeloid45.8
CD34+74
CD4+_Tcells29.05
CD56+_NKCells26.35
CD71+_EarlyErythroid388.95
CD8+_Tcells33.75
CardiacMyocytes120.95
Caudatenucleus32.4
Cerebellum30.4
CerebellumPeduncles58.35
CiliaryGanglion20.3
CingulateCortex59.2
Colorectaladenocarcinoma38
DorsalRootGanglion23.35
FetalThyroid98.65
Fetalbrain76.55
Fetalliver24.95
Fetallung29.2
GlobusPallidus38.45
Heart61.3
Hypothalamus46.25
Kidney29.5
Leukemia_chronicMyelogenousK-562321.9
Leukemia_promyelocytic-HL-60202.85
Leukemialymphoblastic(MOLT-4)80.6
Liver61.2
Lung40.4
Lymphnode25.95
Lymphoma_burkitts(Daudi)172.75
Lymphoma_burkitts(Raji)447.15
MedullaOblongata35.9
OccipitalLobe33.55
OlfactoryBulb36.4
Ovary26.5
Pancreas40.5
PancreaticIslet52.05
ParietalLobe31.95
Pituitary44.3
Placenta106.65
Pons35.35
PrefrontalCortex130.65
Prostate42.3
Salivarygland23.95
SkeletalMuscle131.2
Skin26.35
SmoothMuscle239.65
Spinalcord37.55
SubthalamicNucleus40
SuperiorCervicalGanglion26.6
TemporalLobe53.25
Testis80.45
TestisGermCell99.1
TestisIntersitial60.6
TestisLeydigCell77.9
TestisSeminiferousTubule149.45
Thalamus46.75
Thymus24.85
Thyroid38.9
Tongue67
Tonsil40.1
Trachea15.35
TrigeminalGanglion25.6
Uterus45.95
UterusCorpus32.75
WholeBlood26.05
Wholebrain44.9
colon30.25
pineal_day57.96
pineal_night53.54
retina59.45
small_intestine25.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1288_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.16 ± 0.5
Basal Forebrain5.78 ± 0.17
Basal Part of Pons6.15 ± 0.4
Cerebellar Cortex5.57 ± 0.44
Cerebellar Nuclei5.48 ± 0.43
Claustrum6.55 ± 0.7
Epithalamus5.49 ± 0.42
Frontal Lobe5.71 ± 0.51
Globus Pallidus5.43 ± 0.44
Hypothalamus5.4 ± 0.44
Insula5.76 ± 0.36
Limbic Lobe6.36 ± 0.49
Mesencephalon5.64 ± 0.54
Myelencephalon5.9 ± 0.41
Occipital Lobe6.31 ± 0.5
Parietal Lobe5.97 ± 0.49
Pontine Tegmentum5.81 ± 0.57
Striatum6.41 ± 0.42
Subthalamus5.62 ± 0.13
Temporal Lobe5.85 ± 0.42
Thalamus5.84 ± 0.44
White Matter5.08 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Carm1CBCerebellum6.63
7.89
Carm1CTXCerebral cortex39.07
34.76
Carm1HIPHippocampal region30.91
55.24
Carm1HPFHippocampal formation36.43
51.58
Carm1HYHypothalamus15.68
14.45
Carm1LSXLateral septal complex46.04
45.79
Carm1MBMidbrain8.14
10.99
Carm1MYMedulla8.46
13.2
Carm1OLFOlfactory bulb76.59
80.58
Carm1PPons10.13
13.7
Carm1PALPallidum25.48
27.19
Carm1RHPRetrohippocampal region49.12
47.66
Carm1sAMYStriatum-like amygdalar nuclei62.64
55.56
Carm1STRStriatum31.16
26.94
Carm1STRdStriatum dorsal region20.25
17.11
Carm1STRvStriatum ventral region47.45
38.77
Carm1THThalamus14.52
20.45
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CARM1_HUMAN_2 35 2 36 AAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGAR PRIDE
CARM1_HUMAN_337 10 337 346 QPVVDTFDIR PRIDE
PAp00032766 10 420 429 CLFQSPLFAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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