Annotation Detail for SEMA4B
Basic Information Top
| Gene Symbol: | SEMA4B ( KIAA1745,MGC131831,SEMAC,SemC ) |
|---|---|
| Gene Full Name: | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B |
| Band: | 15q25 |
| Quick Links | Entrez ID:10509; OMIM: NA; Uniprot ID:; ENSEMBL ID: ENSG00000185033; HGNC ID: 10730 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.474935
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 34 / 564012 | 60 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 174 / 1939121 | 89 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 17 / 114246 | 148 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 15 / 119369 | 125 | |
| germ cell tumor | 20 / 263845 | 75 | |
| glioma | 8 / 106883 | 74 | |
| head and neck tumor | 65 / 136302 | 476 |  |
| kidney tumor | 21 / 68959 | 304 | |
| leukemia | 13 / 95842 | 135 | |
| liver tumor | 7 / 96359 | 72 | |
| lung tumor | 14 / 103127 | 135 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 187 / 3360307 | 55 | |
| ovarian tumor | 11 / 76682 | 143 | |
| pancreatic tumor | 59 / 104616 | 563 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 24 / 102680 | 233 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 |  |
| uterine tumor | 11 / 90257 | 121 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 10 / 40015 | 249 | |
| bladder | 3 / 29757 | 100 | |
| blood | 4 / 123478 | 32 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 71 / 1100989 | 64 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 13 / 211054 | 61 | |
| heart | 0 / 89626 | 0 | |
| intestine | 22 / 234472 | 93 | |
| kidney | 28 / 211777 | 132 | |
| larynx | 14 / 24145 | 579 | |
| liver | 7 / 207743 | 33 | |
| lung | 26 / 336974 | 77 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 14 / 91610 | 152 | |
| mammary gland | 14 / 153271 | 91 | |
| mouth | 49 / 67052 | 730 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 14 / 102051 | 137 | |
| pancreas | 70 / 214812 | 325 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 26 / 280825 | 92 | |
| prostate | 26 / 189345 | 137 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 4 / 210574 | 18 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 8 / 96619 | 82 | |
| testis | 27 / 330442 | 81 | |
| thymus | 9 / 81131 | 110 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 17 / 52413 | 324 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 23 / 232878 | 98 | |
| vascular | 4 / 51780 | 77 | |
Microarray in - Probe name: CUST_16641_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.22 ± 0.98 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.74 ± 0.18 | |
| Basal Part of Pons | 1.57 ± 0.38 | |
| Cerebellar Cortex | 2.09 ± 0.68 | |
| Cerebellar Nuclei | 2.08 ± 0.68 | |
| Claustrum | 2.45 ± 0.74 | |
| Epithalamus | 1.69 ± 0.73 | |
| Frontal Lobe | 1.77 ± 0.72 | |
| Globus Pallidus | 2.24 ± 0.58 | |
| Hypothalamus | 1.88 ± 0.62 | |
| Insula | 2 ± 0.8 | |
| Limbic Lobe | 1.88 ± 0.75 | |
| Mesencephalon | 2.03 ± 0.74 | |
| Myelencephalon | 1.91 ± 0.73 | |
| Occipital Lobe | 2.17 ± 0.8 | |
| Parietal Lobe | 1.85 ± 0.72 | |
| Pontine Tegmentum | 1.94 ± 0.68 | |
| Striatum | 1.82 ± 0.68 | |
| Subthalamus | 2.02 ± 0.63 | |
| Temporal Lobe | 1.72 ± 0.63 | |
| Thalamus | 1.81 ± 0.63 | |
| White Matter | 2.53 ± 0.72 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sema4b | CB | Cerebellum | 4.58 | |
| 4.8 | | |||
| Sema4b | CTX | Cerebral cortex | 12.02 | |
| 8.55 | | |||
| Sema4b | HIP | Hippocampal region | 11.49 | |
| 10.52 | | |||
| Sema4b | HPF | Hippocampal formation | 11.32 | |
| 9.33 | | |||
| Sema4b | HY | Hypothalamus | 5 | |
| 4.03 | | |||
| Sema4b | LSX | Lateral septal complex | 6.57 | |
| 4.57 | | |||
| Sema4b | MB | Midbrain | 4.92 | |
| 4.53 | | |||
| Sema4b | MY | Medulla | 4.84 | |
| 5.3 | | |||
| Sema4b | OLF | Olfactory bulb | 14.98 | |
| 11.79 | | |||
| Sema4b | P | Pons | 4.31 | |
| 4.69 | | |||
| Sema4b | PAL | Pallidum | 6.73 | |
| 5.31 | | |||
| Sema4b | RHP | Retrohippocampal region | 10.86 | |
| 7.38 | | |||
| Sema4b | sAMY | Striatum-like amygdalar nuclei | 3.22 | |
| 1.97 | | |||
| Sema4b | STR | Striatum | 5.58 | |
| 4.03 | | |||
| Sema4b | STRd | Striatum dorsal region | 5.41 | |
| 4.06 | | |||
| Sema4b | STRv | Striatum ventral region | 5.7 | |
| 3.89 | | |||
| Sema4b | TH | Thalamus | 5.42 | |
| 4.67 | |