AutismKB 2.0

Annotation Detail for DDX17


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Basic Information Top
Gene Symbol:DDX17 ( DKFZp761H2016,P72,RH70 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
Band: 22q13.1
Quick LinksEntrez ID:10521; OMIM: 608469; Uniprot ID:DDX17_HUMAN; ENSEMBL ID: ENSG00000100201; HGNC ID: 2740
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208719_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts309.05
Adipocyte6.3
AdrenalCortex6.95
Adrenalgland5.7
Amygdala7.1
Appendix6.4
AtrioventricularNode5.75
BDCA4+_DentriticCells111.25
Bonemarrow6.6
BronchialEpithelialCells5.7
CD105+_Endothelial26.5
CD14+_Monocytes170.9
CD19+_BCells(neg._sel.)7.15
CD33+_Myeloid133.1
CD34+28.15
CD4+_Tcells233.95
CD56+_NKCells7.9
CD71+_EarlyErythroid6.35
CD8+_Tcells15.15
CardiacMyocytes10
Caudatenucleus9.3
Cerebellum5.35
CerebellumPeduncles7.85
CiliaryGanglion5.1
CingulateCortex6.9
Colorectaladenocarcinoma6.35
DorsalRootGanglion5.15
FetalThyroid8.3
Fetalbrain6.75
Fetalliver6.1
Fetallung37.65
GlobusPallidus5.15
Heart8.1
Hypothalamus7
Kidney17.85
Leukemia_chronicMyelogenousK-5626
Leukemia_promyelocytic-HL-6057
Leukemialymphoblastic(MOLT-4)5.2
Liver9.15
Lung6.65
Lymphnode26.8
Lymphoma_burkitts(Daudi)8.4
Lymphoma_burkitts(Raji)42.15
MedullaOblongata5.9
OccipitalLobe9.7
OlfactoryBulb8.95
Ovary4
Pancreas5.15
PancreaticIslet7.1
ParietalLobe7.1
Pituitary7.55
Placenta8
Pons6
PrefrontalCortex33.35
Prostate7.2
Salivarygland5.25
SkeletalMuscle7.75
Skin5.1
SmoothMuscle6.95
Spinalcord17.7
SubthalamicNucleus6.75
SuperiorCervicalGanglion7.5
TemporalLobe6.15
Testis5.4
TestisGermCell38.7
TestisIntersitial5.6
TestisLeydigCell6.7
TestisSeminiferousTubule5.55
Thalamus7.05
Thymus6.1
Thyroid8.25
Tongue6.8
Tonsil6.35
Trachea5.6
TrigeminalGanglion6.65
Uterus5.1
UterusCorpus8.95
WholeBlood12.05
Wholebrain5.05
colon6.3
pineal_day180.94
pineal_night333.26
retina10.8
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P218784
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.02 ± 0.2
Basal Forebrain10.48 ± 0.17
Basal Part of Pons10.16 ± 0.2
Cerebellar Cortex10.62 ± 0.18
Cerebellar Nuclei10.35 ± 0.11
Claustrum9.99 ± 0.46
Epithalamus11.13 ± 0.5
Frontal Lobe10.22 ± 0.36
Globus Pallidus10.77 ± 0.44
Hypothalamus10.36 ± 0.31
Insula10.26 ± 0.25
Limbic Lobe10.11 ± 0.32
Mesencephalon10.39 ± 0.38
Myelencephalon10.31 ± 0.39
Occipital Lobe10.42 ± 0.22
Parietal Lobe10.33 ± 0.34
Pontine Tegmentum10.32 ± 0.37
Striatum10.48 ± 0.44
Subthalamus10.38 ± 0
Temporal Lobe10.24 ± 0.23
Thalamus10.42 ± 0.3
White Matter11.68 ± 0.17
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DDX17_HUMAN_165 11 165 175 GPICLVLAPTR PRIDE
DDX17_HUMAN_212 14 212 225 LERGVEICIATPGR PRIDE
DDX17_HUMAN_240 11 240 250 CTYLVLDEADR PRIDE
DDX17_HUMAN_286 8 286 293 QLAEDFLR PRIDE
DDX17_HUMAN_387 15 387 401 SGKAPILIATDVASR PRIDE
DDX17_HUMAN_469 8 469 476 LMQLVDHR PRIDE
PAp00001430 11 240 250 CTYLVLDEADR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018