AutismKB 2.0

Annotation Detail for ATG7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ATG7 ( APG7-LIKE,APG7L,DKFZp434N0735,GSA7 )
Gene Full Name: ATG7 autophagy related 7 homolog (S. cerevisiae)
Band: 3p25.3
Quick LinksEntrez ID:10533; OMIM: 608760; Uniprot ID:ATG7_HUMAN; ENSEMBL ID: ENSG00000197548; HGNC ID: 16935
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst2 / 6231932
fetus40 / 56401270
neonate3 / 3109796
infant3 / 23620127
juvenile1 / 5555617
adult129 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor15 / 26384556
glioma11 / 106883102
head and neck tumor7 / 13630251
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor12 / 96359124
lung tumor5 / 10312748
lymphoma5 / 7175569
non-neoplasia6 / 9725061
normal238 / 336030770
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor14 / 124949112
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder2 / 2975767
blood7 / 12347856
bone1 / 7165513
bone marrow8 / 48801163
brain81 / 110098973
cervix5 / 48171103
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye10 / 21105447
heart11 / 89626122
intestine24 / 234472102
kidney12 / 21177756
larynx1 / 2414541
liver15 / 20774372
lung23 / 33697468
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth3 / 6705244
muscle5 / 10771546
nerve0 / 157680 
ovary9 / 10205188
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta24 / 28082585
prostate11 / 18934558
salivary gland1 / 2015549
skin23 / 210574109
spleen3 / 5395255
stomach5 / 9661951
testis16 / 33044248
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord1 / 1368073
uterus11 / 23287847
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218673_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.9
Adipocyte3.4
AdrenalCortex3.55
Adrenalgland2.9
Amygdala3.7
Appendix3.45
AtrioventricularNode2.75
BDCA4+_DentriticCells5.6
Bonemarrow3.4
BronchialEpithelialCells3.45
CD105+_Endothelial4.25
CD14+_Monocytes21.3
CD19+_BCells(neg._sel.)3.7
CD33+_Myeloid17.7
CD34+5
CD4+_Tcells3.75
CD56+_NKCells5.9
CD71+_EarlyErythroid3.25
CD8+_Tcells3.4
CardiacMyocytes4.3
Caudatenucleus3.05
Cerebellum2.8
CerebellumPeduncles3.85
CiliaryGanglion2.5
CingulateCortex3.55
Colorectaladenocarcinoma3.45
DorsalRootGanglion2.6
FetalThyroid3.35
Fetalbrain3.4
Fetalliver2.95
Fetallung2.9
GlobusPallidus2.5
Heart4.35
Hypothalamus3.85
Kidney2.75
Leukemia_chronicMyelogenousK-5623.2
Leukemia_promyelocytic-HL-603
Leukemialymphoblastic(MOLT-4)2.7
Liver4.6
Lung4.1
Lymphnode3
Lymphoma_burkitts(Daudi)4.4
Lymphoma_burkitts(Raji)4.8
MedullaOblongata3.25
OccipitalLobe3.1
OlfactoryBulb2.7
Ovary2.25
Pancreas2.7
PancreaticIslet3.7
ParietalLobe3.65
Pituitary3.95
Placenta3.7
Pons3.3
PrefrontalCortex4.85
Prostate4.25
Salivarygland2.75
SkeletalMuscle3.9
Skin2.6
SmoothMuscle6
Spinalcord3.7
SubthalamicNucleus3.1
SuperiorCervicalGanglion4.35
TemporalLobe3.15
Testis3.9
TestisGermCell2.9
TestisIntersitial2.9
TestisLeydigCell3.4
TestisSeminiferousTubule3.05
Thalamus3.5
Thymus2.8
Thyroid4.4
Tongue3.3
Tonsil3.4
Trachea2.85
TrigeminalGanglion3.4
Uterus2.95
UterusCorpus3.05
WholeBlood12.85
Wholebrain6
colon3.5
pineal_day4.34
pineal_night4.24
retina4.275
small_intestine3.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P143987
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.86 ± 0.53
Basal Forebrain6.09 ± 0.27
Basal Part of Pons6.41 ± 0.38
Cerebellar Cortex6.05 ± 0.37
Cerebellar Nuclei5.88 ± 0.6
Claustrum5.63 ± 0.65
Epithalamus6.22 ± 0.54
Frontal Lobe6.35 ± 0.36
Globus Pallidus5.78 ± 0.33
Hypothalamus6.17 ± 0.24
Insula6.38 ± 0.26
Limbic Lobe6.13 ± 0.53
Mesencephalon6.1 ± 0.45
Myelencephalon6.11 ± 0.5
Occipital Lobe5.85 ± 0.43
Parietal Lobe6.17 ± 0.47
Pontine Tegmentum6.07 ± 0.55
Striatum5.74 ± 0.82
Subthalamus5.5 ± 0.71
Temporal Lobe6.32 ± 0.45
Thalamus6.13 ± 0.44
White Matter5.97 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Atg7CBCerebellum2.44
2.49
Atg7CTXCerebral cortex2.76
2
Atg7HIPHippocampal region4.32
3.49
Atg7HPFHippocampal formation5.52
4.44
Atg7HYHypothalamus3.23
3.75
Atg7LSXLateral septal complex0.31
0.19
Atg7MBMidbrain2.69
3.56
Atg7MYMedulla8.23
8.93
Atg7OLFOlfactory bulb9.78
8.36
Atg7PPons6.93
8.61
Atg7PALPallidum1.16
1.03
Atg7RHPRetrohippocampal region9.76
7.38
Atg7sAMYStriatum-like amygdalar nuclei0.74
0.42
Atg7STRStriatum0.91
0.65
Atg7STRdStriatum dorsal region0.77
0.56
Atg7STRvStriatum ventral region1.95
1.36
Atg7THThalamus3.17
2.4
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ATG7_HUMAN_102 15 102 116 LLLEQAANEIWESIK PRIDE
ATG7_HUMAN_432 24 432 455 GFNMSIPMPGHPVNFSSVTLEQAR PRIDE
PAp00006454 31 517 547 QQGAGDLCPNHPVASADLLGSSLFANIPGYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved