AutismKB 2.0

Annotation Detail for MRPL28


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Basic Information Top
Gene Symbol:MRPL28 ( MAAT1,MGC8499,p15 )
Gene Full Name: mitochondrial ribosomal protein L28
Band: 16p13.3
Quick LinksEntrez ID:10573; OMIM: 604853; Uniprot ID:RM28_HUMAN; ENSEMBL ID: ENSG00000086504; HGNC ID: 14484
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus13 / 56401223
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult130 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor16 / 26384560
glioma14 / 106883130
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia13 / 95842135
liver tumor5 / 9635951
lung tumor21 / 103127203
lymphoma11 / 71755153
non-neoplasia2 / 9725020
normal141 / 336030741
ovarian tumor3 / 7668239
pancreatic tumor20 / 104616191
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer9 / 10268087
retinoblastoma7 / 46356151
skin tumor57 / 124949456
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites9 / 40015224
bladder1 / 2975733
blood15 / 123478121
bone4 / 7165555
bone marrow1 / 4880120
brain58 / 110098952
cervix6 / 48171124
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus0 / 202090 
eye15 / 21105471
heart2 / 8962622
intestine12 / 23447251
kidney10 / 21177747
larynx0 / 241450 
liver7 / 20774333
lung40 / 336974118
lymph8 / 44270180
lymph node1 / 9161010
mammary gland9 / 15327158
mouth3 / 6705244
muscle18 / 107715167
nerve1 / 1576863
ovary6 / 10205158
pancreas24 / 214812111
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate12 / 18934563
salivary gland1 / 2015549
skin58 / 210574275
spleen1 / 5395218
stomach2 / 9661920
testis4 / 33044212
thymus1 / 8113112
thyroid1 / 4747321
tonsil4 / 16999235
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204599_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts366.6
Adipocyte135.55
AdrenalCortex182.15
Adrenalgland131.25
Amygdala146.25
Appendix147.75
AtrioventricularNode125.8
BDCA4+_DentriticCells232.55
Bonemarrow152
BronchialEpithelialCells175.25
CD105+_Endothelial229.3
CD14+_Monocytes171.7
CD19+_BCells(neg._sel.)140.75
CD33+_Myeloid358.9
CD34+189.85
CD4+_Tcells130.55
CD56+_NKCells221.85
CD71+_EarlyErythroid157.35
CD8+_Tcells138.85
CardiacMyocytes172.2
Caudatenucleus118.65
Cerebellum107.85
CerebellumPeduncles159.95
CiliaryGanglion106.2
CingulateCortex159.95
Colorectaladenocarcinoma167.45
DorsalRootGanglion138.8
FetalThyroid127.45
Fetalbrain153.45
Fetalliver123.5
Fetallung113.95
GlobusPallidus108.35
Heart261
Hypothalamus169.75
Kidney120.15
Leukemia_chronicMyelogenousK-562148.6
Leukemia_promyelocytic-HL-60131.2
Leukemialymphoblastic(MOLT-4)167.95
Liver235
Lung203.8
Lymphnode128.95
Lymphoma_burkitts(Daudi)223.5
Lymphoma_burkitts(Raji)344.25
MedullaOblongata135.35
OccipitalLobe123.45
OlfactoryBulb114.9
Ovary103.45
Pancreas109.7
PancreaticIslet149.55
ParietalLobe160.45
Pituitary170.25
Placenta106.9
Pons140.25
PrefrontalCortex186.1
Prostate243.1
Salivarygland117.8
SkeletalMuscle166.8
Skin133.8
SmoothMuscle168.25
Spinalcord138.55
SubthalamicNucleus151.6
SuperiorCervicalGanglion173.85
TemporalLobe163.75
Testis150.9
TestisGermCell121.75
TestisIntersitial124.05
TestisLeydigCell133.1
TestisSeminiferousTubule146.3
Thalamus169.65
Thymus117.1
Thyroid206.85
Tongue140.45
Tonsil150.25
Trachea108.2
TrigeminalGanglion145.9
Uterus116.85
UterusCorpus119.95
WholeBlood150.05
Wholebrain190
colon126.95
pineal_day209.56
pineal_night186.68
retina160.8
small_intestine104.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1062_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.49 ± 0.75
Basal Forebrain7.66 ± 0.29
Basal Part of Pons8.24 ± 0.71
Cerebellar Cortex7.58 ± 0.41
Cerebellar Nuclei7.42 ± 0.37
Claustrum7.44 ± 0.81
Epithalamus7.92 ± 0.33
Frontal Lobe8.11 ± 0.51
Globus Pallidus6.94 ± 0.49
Hypothalamus8.08 ± 0.39
Insula8.09 ± 0.38
Limbic Lobe7.74 ± 0.76
Mesencephalon7.54 ± 0.58
Myelencephalon7.78 ± 0.68
Occipital Lobe7.06 ± 0.72
Parietal Lobe7.79 ± 0.58
Pontine Tegmentum7.72 ± 0.53
Striatum7.7 ± 0.68
Subthalamus7.72 ± 0.37
Temporal Lobe8.12 ± 0.53
Thalamus7.64 ± 0.43
White Matter6.91 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mrpl28CBCerebellum13.82
21
Mrpl28CTXCerebral cortex45.5
38.31
Mrpl28HIPHippocampal region27.45
37.54
Mrpl28HPFHippocampal formation21.24
25.98
Mrpl28HYHypothalamus12.74
11.71
Mrpl28LSXLateral septal complex1.82
1.28
Mrpl28MBMidbrain19.15
20.99
Mrpl28MYMedulla21.1
30.47
Mrpl28OLFOlfactory bulb30
26.4
Mrpl28PPons18.04
25.49
Mrpl28PALPallidum13.86
14.86
Mrpl28RHPRetrohippocampal region12.61
12.16
Mrpl28sAMYStriatum-like amygdalar nuclei7.45
6.51
Mrpl28STRStriatum6.59
5.21
Mrpl28STRdStriatum dorsal region4.63
3.68
Mrpl28STRvStriatum ventral region16.23
11.76
Mrpl28THThalamus30.49
29.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00130928 22 193 214 EFAIPEEEAEWVGLTLEEAIEK Peptide Atlas
RM28_HUMAN_228 24 228 251 IYVAELIQQLQQQALSEPAVVQKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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