Annotation Detail for TACC2
Basic Information Top
| Gene Symbol: | TACC2 ( AZU-1,ECTACC ) |
|---|---|
| Gene Full Name: | transforming, acidic coiled-coil containing protein 2 |
| Band: | 10q26.13 |
| Quick Links | Entrez ID:10579; OMIM: 605302; Uniprot ID:TACC2_HUMAN; ENSEMBL ID: ENSG00000138162; HGNC ID: 11523 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.713875
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 30 / 564012 | 53 |  |
| neonate | 3 / 31097 | 96 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 232 / 1939121 | 119 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 1 / 1939121 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 32 / 114246 | 280 |  |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 29 / 119369 | 242 | |
| germ cell tumor | 9 / 263845 | 34 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 39 / 136302 | 286 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 228 / 3360307 | 67 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 |  |
| prostate cancer | 14 / 102680 | 136 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 4 / 90257 | 44 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 2 / 3360307 | 0 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 47 / 1100989 | 42 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 6 / 211054 | 28 | |
| heart | 4 / 89626 | 44 | |
| intestine | 41 / 234472 | 174 | |
| kidney | 13 / 211777 | 61 | |
| larynx | 5 / 24145 | 207 | |
| liver | 8 / 207743 | 38 | |
| lung | 37 / 336974 | 109 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 24 / 67052 | 357 | |
| muscle | 9 / 107715 | 83 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 4 / 41328 | 96 | |
| pituitary gland | 3 / 16585 | 180 | |
| placenta | 75 / 280825 | 267 | |
| prostate | 18 / 189345 | 95 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 19 / 210574 | 90 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 26 / 96619 | 269 | |
| testis | 8 / 330442 | 24 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 8 / 47473 | 168 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 9 / 52413 | 171 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 13 / 232878 | 55 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 3 / 336974 | 8 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 211382_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.35 | |
| Adipocyte | 4.7 | |
| AdrenalCortex | 5.2 | |
| Adrenalgland | 4.25 | |
| Amygdala | 7.15 | |
| Appendix | 5.6 | |
| AtrioventricularNode | 4 | |
| BDCA4+_DentriticCells | 4.95 | |
| Bonemarrow | 4.85 | |
| BronchialEpithelialCells | 5.95 | |
| CD105+_Endothelial | 5.35 | |
| CD14+_Monocytes | 5 | |
| CD19+_BCells(neg._sel.) | 5 | |
| CD33+_Myeloid | 6.55 | |
| CD34+ | 6.65 | |
| CD4+_Tcells | 5.6 | |
| CD56+_NKCells | 6.25 | |
| CD71+_EarlyErythroid | 4.7 | |
| CD8+_Tcells | 5.05 | |
| CardiacMyocytes | 6.75 | |
| Caudatenucleus | 6.5 | |
| Cerebellum | 6.4 | |
| CerebellumPeduncles | 6.55 | |
| CiliaryGanglion | 3.5 | |
| CingulateCortex | 8.6 | |
| Colorectaladenocarcinoma | 5.65 | |
| DorsalRootGanglion | 4.55 | |
| FetalThyroid | 8.5 | |
| Fetalbrain | 14.25 | |
| Fetalliver | 4.6 | |
| Fetallung | 8.65 | |
| GlobusPallidus | 4.2 | |
| Heart | 96.25 | |
| Hypothalamus | 6.35 | |
| Kidney | 5.65 | |
| Leukemia_chronicMyelogenousK-562 | 4.8 | |
| Leukemia_promyelocytic-HL-60 | 3.3 | |
| Leukemialymphoblastic(MOLT-4) | 3.5 | |
| Liver | 7.85 | |
| Lung | 115.7 | |
| Lymphnode | 4 | |
| Lymphoma_burkitts(Daudi) | 6.4 | |
| Lymphoma_burkitts(Raji) | 6.55 | |
| MedullaOblongata | 5.25 | |
| OccipitalLobe | 5.55 | |
| OlfactoryBulb | 5.85 | |
| Ovary | 3.3 | |
| Pancreas | 4.65 | |
| PancreaticIslet | 5.9 | |
| ParietalLobe | 6.1 | |
| Pituitary | 11.3 | |
| Placenta | 255 | |
| Pons | 5.35 | |
| PrefrontalCortex | 12.6 | |
| Prostate | 67.25 | |
| Salivarygland | 11.05 | |
| SkeletalMuscle | 8.35 | |
| Skin | 9.3 | |
| SmoothMuscle | 6.1 | |
| Spinalcord | 4.9 | |
| SubthalamicNucleus | 5 | |
| SuperiorCervicalGanglion | 6.8 | |
| TemporalLobe | 5.2 | |
| Testis | 5.05 | |
| TestisGermCell | 4.45 | |
| TestisIntersitial | 4.25 | |
| TestisLeydigCell | 5.1 | |
| TestisSeminiferousTubule | 4.7 | |
| Thalamus | 5.85 | |
| Thymus | 4.2 | |
| Thyroid | 42.8 | |
| Tongue | 11.35 | |
| Tonsil | 5.05 | |
| Trachea | 10 | |
| TrigeminalGanglion | 4.6 | |
| Uterus | 9.5 | |
| UterusCorpus | 4.7 | |
| WholeBlood | 4 | |
| Wholebrain | 8.2 | |
| colon | 17.85 | |
| pineal_day | 24.72 | |
| pineal_night | 28.32 | |
| retina | 35.05 | |
| small_intestine | 17.85 | |
- Probe name: A_32_P12169
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.7 ± 1.11 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.28 ± 0.29 | |
| Basal Part of Pons | 1.92 ± 0.48 | |
| Cerebellar Cortex | 2.06 ± 0.85 | |
| Cerebellar Nuclei | 2.6 ± 0.84 | |
| Claustrum | 3.07 ± 0.91 | |
| Epithalamus | 2.03 ± 0.59 | |
| Frontal Lobe | 2.08 ± 0.69 | |
| Globus Pallidus | 2.92 ± 0.47 | |
| Hypothalamus | 2.31 ± 0.61 | |
| Insula | 2.09 ± 0.48 | |
| Limbic Lobe | 2.3 ± 0.78 | |
| Mesencephalon | 2.36 ± 0.73 | |
| Myelencephalon | 2.3 ± 0.71 | |
| Occipital Lobe | 2.62 ± 1.26 | |
| Parietal Lobe | 2.3 ± 0.91 | |
| Pontine Tegmentum | 2.38 ± 0.91 | |
| Striatum | 2.57 ± 0.89 | |
| Subthalamus | 2.29 ± 0.65 | |
| Temporal Lobe | 2.11 ± 0.71 | |
| Thalamus | 2.18 ± 0.67 | |
| White Matter | 2.82 ± 0.31 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Tacc2 | CB | Cerebellum | 29.16 | |
| 44.36 | | |||
| Tacc2 | CTX | Cerebral cortex | 97.98 | |
| 81.44 | | |||
| Tacc2 | HIP | Hippocampal region | 69.19 | |
| 100 | | |||
| Tacc2 | HPF | Hippocampal formation | 76.8 | |
| 100 | | |||
| Tacc2 | HY | Hypothalamus | 31.77 | |
| 25.75 | | |||
| Tacc2 | LSX | Lateral septal complex | 82.7 | |
| 65.94 | | |||
| Tacc2 | MB | Midbrain | 15.82 | |
| 17.85 | | |||
| Tacc2 | MY | Medulla | 10.7 | |
| 16.28 | | |||
| Tacc2 | OLF | Olfactory bulb | 85.04 | |
| 78.4 | | |||
| Tacc2 | P | Pons | 12.27 | |
| 18.14 | | |||
| Tacc2 | PAL | Pallidum | 35.5 | |
| 33.33 | | |||
| Tacc2 | RHP | Retrohippocampal region | 87.59 | |
| 89.93 | | |||
| Tacc2 | sAMY | Striatum-like amygdalar nuclei | 74.59 | |
| 59.35 | | |||
| Tacc2 | STR | Striatum | 41.94 | |
| 31.28 | | |||
| Tacc2 | STRd | Striatum dorsal region | 30.97 | |
| 22.49 | | |||
| Tacc2 | STRv | Striatum ventral region | 45.99 | |
| 32.75 | | |||
| Tacc2 | TH | Thalamus | 48.92 | |
| 44.18 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00011256 | 9 | 936 | 944 | RCAQEYLSR | Peptide Atlas |