Annotation Detail for TXNRD2
Basic Information Top
| Gene Symbol: | TXNRD2 ( SELZ,TR,TR-BETA,TR3,TRXR2 ) |
|---|---|
| Gene Full Name: | thioredoxin reductase 2 |
| Band: | 22q11.21 |
| Quick Links | Entrez ID:10587; OMIM: 606448; Uniprot ID:TRXR2_HUMAN; ENSEMBL ID: ENSG00000184470; HGNC ID: 18155 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.443430
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 21 / 564012 | 37 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 2 / 23620 | 84 |  |
| juvenile | 0 / 55556 | 0 | |
| adult | 97 / 1939121 | 50 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 3 / 12794 | 234 |  |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 12 / 96359 | 124 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 158 / 3360307 | 47 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 6 / 104616 | 57 | |
| primitive neuroectodermal tumor of the CNS | 29 / 125680 | 230 | |
| prostate cancer | 13 / 102680 | 126 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 6 / 124949 | 48 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 2 / 29757 | 67 | |
| blood | 4 / 123478 | 32 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 40 / 1100989 | 36 | |
| cervix | 18 / 48171 | 373 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 10 / 211054 | 47 | |
| heart | 2 / 89626 | 22 | |
| intestine | 11 / 234472 | 46 | |
| kidney | 2 / 211777 | 9 |  |
| larynx | 0 / 24145 | 0 | |
| liver | 12 / 207743 | 57 | |
| lung | 16 / 336974 | 47 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 10 / 102051 | 97 | |
| pancreas | 20 / 214812 | 93 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 19 / 280825 | 67 | |
| prostate | 23 / 189345 | 121 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 7 / 210574 | 33 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 1 / 96619 | 10 | |
| testis | 13 / 330442 | 39 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 7 / 232878 | 30 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_14175_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5 ± 0.59 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.69 ± 0.29 | |
| Basal Part of Pons | 4.63 ± 0.43 | |
| Cerebellar Cortex | 5.24 ± 0.27 | |
| Cerebellar Nuclei | 4.49 ± 0.66 | |
| Claustrum | 4.66 ± 0.5 | |
| Epithalamus | 4.69 ± 0.33 | |
| Frontal Lobe | 4.51 ± 0.52 | |
| Globus Pallidus | 4.56 ± 0.54 | |
| Hypothalamus | 4.19 ± 0.61 | |
| Insula | 4.73 ± 0.46 | |
| Limbic Lobe | 4.89 ± 0.57 | |
| Mesencephalon | 4.69 ± 0.62 | |
| Myelencephalon | 4.65 ± 0.51 | |
| Occipital Lobe | 5.2 ± 0.67 | |
| Parietal Lobe | 4.77 ± 0.39 | |
| Pontine Tegmentum | 4.84 ± 0.57 | |
| Striatum | 4.82 ± 0.52 | |
| Subthalamus | 4.39 ± 0.39 | |
| Temporal Lobe | 4.69 ± 0.48 | |
| Thalamus | 4.58 ± 0.41 | |
| White Matter | 4.8 ± 0.56 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Txnrd2 | CB | Cerebellum | 0.16 | |
| 0.59 | | |||
| Txnrd2 | CTX | Cerebral cortex | 0.29 | |
| 0.56 | | |||
| Txnrd2 | HIP | Hippocampal region | 0.26 | |
| 0.3 | | |||
| Txnrd2 | HPF | Hippocampal formation | 0.2 | |
| 0.23 | | |||
| Txnrd2 | HY | Hypothalamus | 1.33 | |
| 2.36 | | |||
| Txnrd2 | LSX | Lateral septal complex | 0.08 | |
| 0.04 | | |||
| Txnrd2 | MB | Midbrain | 0.47 | |
| 1.34 | | |||
| Txnrd2 | MY | Medulla | 0.32 | |
| 0.98 | | |||
| Txnrd2 | OLF | Olfactory bulb | 0.8 | |
| 2.59 | | |||
| Txnrd2 | P | Pons | 1.69 | |
| 4.06 | | |||
| Txnrd2 | PAL | Pallidum | 0.41 | |
| 1.19 | | |||
| Txnrd2 | RHP | Retrohippocampal region | 0.08 | |
| 0.11 | | |||
| Txnrd2 | sAMY | Striatum-like amygdalar nuclei | 0.41 | |
| 0.65 | | |||
| Txnrd2 | STR | Striatum | 0.26 | |
| 0.5 | | |||
| Txnrd2 | STRd | Striatum dorsal region | 0.12 | |
| 0.13 | | |||
| Txnrd2 | STRv | Striatum ventral region | 0.69 | |
| 1.32 | | |||
| Txnrd2 | TH | Thalamus | 0.1 | |
| 0.08 | |