AutismKB 2.0

Annotation Detail for CENPC1


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Basic Information Top
Gene Symbol:CENPC1 ( CENP-C,CENPC,MIF2,hcp-4 )
Gene Full Name: centromere protein C 1
Band: 4q13.2
Quick LinksEntrez ID:1060; OMIM: 117141; Uniprot ID:CENPC_HUMAN; ENSEMBL ID: ENSG00000145241; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal117 / 336030734
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine6 / 23447225
kidney12 / 21177756
larynx0 / 241450 
liver4 / 20774319
lung4 / 33697411
lymph0 / 442700 
lymph node10 / 91610109
mammary gland4 / 15327126
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary1 / 1020519
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta9 / 28082532
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach0 / 966190 
testis12 / 33044236
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204739_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.5
Adipocyte6.15
AdrenalCortex7.85
Adrenalgland5.65
Amygdala6.65
Appendix8.5
AtrioventricularNode6.25
BDCA4+_DentriticCells23.2
Bonemarrow6.55
BronchialEpithelialCells6.2
CD105+_Endothelial19.95
CD14+_Monocytes9.25
CD19+_BCells(neg._sel.)22.7
CD33+_Myeloid21.5
CD34+21.05
CD4+_Tcells34.35
CD56+_NKCells56.95
CD71+_EarlyErythroid13.05
CD8+_Tcells27.3
CardiacMyocytes9.6
Caudatenucleus5.9
Cerebellum5.15
CerebellumPeduncles7.95
CiliaryGanglion8.5
CingulateCortex6.9
Colorectaladenocarcinoma6.5
DorsalRootGanglion5.85
FetalThyroid6.5
Fetalbrain6.25
Fetalliver5.9
Fetallung5.15
GlobusPallidus5.2
Heart8.9
Hypothalamus6.75
Kidney5.4
Leukemia_chronicMyelogenousK-5626
Leukemia_promyelocytic-HL-6014.75
Leukemialymphoblastic(MOLT-4)22.9
Liver8.8
Lung6.65
Lymphnode6.2
Lymphoma_burkitts(Daudi)13.15
Lymphoma_burkitts(Raji)9.35
MedullaOblongata5.95
OccipitalLobe5.8
OlfactoryBulb5.1
Ovary4.7
Pancreas5.35
PancreaticIslet7.3
ParietalLobe7.3
Pituitary7.6
Placenta6.35
Pons6.5
PrefrontalCortex8.15
Prostate7.35
Salivarygland5.5
SkeletalMuscle9.15
Skin7.95
SmoothMuscle7.2
Spinalcord6.9
SubthalamicNucleus6.8
SuperiorCervicalGanglion10
TemporalLobe6.05
Testis5.3
TestisGermCell5.6
TestisIntersitial11.25
TestisLeydigCell6.75
TestisSeminiferousTubule7.2
Thalamus6.95
Thymus4.8
Thyroid9.1
Tongue7.05
Tonsil6.55
Trachea5.45
TrigeminalGanglion7.8
Uterus6.85
UterusCorpus6.1
WholeBlood7.2
Wholebrain5.1
colon6.45
pineal_day8.22
pineal_night8.24
retina7.9
small_intestine6.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P167194
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.44 ± 0.32
Basal Forebrain10.15 ± 0.11
Basal Part of Pons9.88 ± 0.2
Cerebellar Cortex10.31 ± 0.19
Cerebellar Nuclei9.67 ± 0.24
Claustrum10.32 ± 0.33
Epithalamus10.21 ± 0.27
Frontal Lobe9.83 ± 0.27
Globus Pallidus10.03 ± 0.24
Hypothalamus10.13 ± 0.21
Insula9.98 ± 0.29
Limbic Lobe10.11 ± 0.39
Mesencephalon10.2 ± 0.33
Myelencephalon10.09 ± 0.35
Occipital Lobe10.5 ± 0.32
Parietal Lobe10.08 ± 0.29
Pontine Tegmentum10.03 ± 0.3
Striatum10.48 ± 0.36
Subthalamus10.08 ± 0
Temporal Lobe10.06 ± 0.25
Thalamus10.04 ± 0.17
White Matter10.85 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cenpc1CBCerebellum21.53
22.96
Cenpc1CTXCerebral cortex44.45
31.07
Cenpc1HIPHippocampal region34.4
37.23
Cenpc1HPFHippocampal formation39.85
37.3
Cenpc1HYHypothalamus13.63
10.39
Cenpc1LSXLateral septal complex6.73
4.24
Cenpc1MBMidbrain19.81
16.52
Cenpc1MYMedulla22.75
21.82
Cenpc1OLFOlfactory bulb39.34
30.1
Cenpc1PPons21.03
20.06
Cenpc1PALPallidum17.02
14.01
Cenpc1RHPRetrohippocampal region49.85
38.44
Cenpc1sAMYStriatum-like amygdalar nuclei12.25
8.55
Cenpc1STRStriatum20.37
13.91
Cenpc1STRdStriatum dorsal region20.83
14.28
Cenpc1STRvStriatum ventral region28.64
18.6
Cenpc1THThalamus32.88
25.27
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CENPC_HUMAN_167 14 167 180 TSVSQNVIPSSAKK PRIDE
CENPC_HUMAN_316 7 316 322 SWITIPR PRIDE
CENPC_HUMAN_331 14 331 344 TISPAESTALFQGR PRIDE
CENPC_HUMAN_535 13 535 547 SEESPVYSNSSVR PRIDE
PAp00032796 16 612 627 CSLSEPLESDEADLAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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