Annotation Detail for SH2B2
Basic Information Top
| Gene Symbol: | SH2B2 ( APS ) |
|---|---|
| Gene Full Name: | SH2B adaptor protein 2 |
| Band: | 7q22.1 |
| Quick Links | Entrez ID:10603; OMIM: 605300; Uniprot ID:SH2B2_HUMAN; ENSEMBL ID: ENSG00000160999; HGNC ID: 17381 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.489448
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 7 / 564012 | 12 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 7 / 1939121 | 3 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 6 / 95842 | 62 |  |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 10 / 71755 | 139 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 31 / 3360307 | 9 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 8 / 125191 | 63 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 5 / 1100989 | 4 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 1 / 89626 | 11 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 3 / 336974 | 8 | |
| lymph | 10 / 44270 | 225 |  |
| lymph node | 14 / 91610 | 152 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 0 / 210574 | 0 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P59507
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.8 ± 0.4 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.84 ± 0.45 | |
| Basal Part of Pons | 4.78 ± 0.31 | |
| Cerebellar Cortex | 4.99 ± 0.37 | |
| Cerebellar Nuclei | 5.08 ± 0.34 | |
| Claustrum | 4.89 ± 0.7 | |
| Epithalamus | 4.35 ± 0.7 | |
| Frontal Lobe | 4.96 ± 0.51 | |
| Globus Pallidus | 5.2 ± 0.51 | |
| Hypothalamus | 5.25 ± 0.6 | |
| Insula | 4.9 ± 0.22 | |
| Limbic Lobe | 4.77 ± 0.54 | |
| Mesencephalon | 5.18 ± 0.59 | |
| Myelencephalon | 5.03 ± 0.61 | |
| Occipital Lobe | 4.93 ± 0.63 | |
| Parietal Lobe | 4.89 ± 0.55 | |
| Pontine Tegmentum | 4.87 ± 0.44 | |
| Striatum | 5.06 ± 0.63 | |
| Subthalamus | 4.88 ± 0.38 | |
| Temporal Lobe | 4.88 ± 0.53 | |
| Thalamus | 5.28 ± 0.53 | |
| White Matter | 3.77 ± 0.5 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sh2b2 | CB | Cerebellum | 6.66 | |
| 7.55 | | |||
| Sh2b2 | CTX | Cerebral cortex | 7.45 | |
| 5.24 | | |||
| Sh2b2 | HIP | Hippocampal region | 1.56 | |
| 1.43 | | |||
| Sh2b2 | HPF | Hippocampal formation | 1.87 | |
| 1.49 | | |||
| Sh2b2 | HY | Hypothalamus | 1.38 | |
| 0.94 | | |||
| Sh2b2 | LSX | Lateral septal complex | 0.63 | |
| 0.57 | | |||
| Sh2b2 | MB | Midbrain | 2.46 | |
| 2.19 | | |||
| Sh2b2 | MY | Medulla | 4.73 | |
| 4.49 | | |||
| Sh2b2 | OLF | Olfactory bulb | 8.08 | |
| 6.32 | | |||
| Sh2b2 | P | Pons | 2.86 | |
| 2.65 | | |||
| Sh2b2 | PAL | Pallidum | 3.79 | |
| 3.06 | | |||
| Sh2b2 | RHP | Retrohippocampal region | 2.43 | |
| 1.6 | | |||
| Sh2b2 | sAMY | Striatum-like amygdalar nuclei | 3.36 | |
| 2.24 | | |||
| Sh2b2 | STR | Striatum | 2.02 | |
| 1.52 | | |||
| Sh2b2 | STRd | Striatum dorsal region | 1.11 | |
| 0.91 | | |||
| Sh2b2 | STRv | Striatum ventral region | 5.13 | |
| 3.51 | | |||
| Sh2b2 | TH | Thalamus | 1.53 | |
| 1.26 | |